A randomized study of fever prophylaxis and the immunogenicity of routine pediatric vaccinations - Wysocki, Jacek; Center, Kimberly J.; Brzostek, Jerzy; Majda-Stanislawska, Ewa; Szymanski, Henryk; Szenborn, Leszek; Czajka, Hanna; Hasiec, Barbara; Dziduch, Jerzy; Jackowska, Teresa; Witor, Anita; Kopińska, Elżbieta; et al. (Vaccine, 2017)
Keywords: acetaminophen; Acetaminophen - administration & dosage; Allergy and Immunology; Analgesics; antibodies; Antibodies, Bacterial - blood; Antigens; Antipyretic; antipyretics; Antipyretics - administration & dosage; Chemoprevention - methods; Combined vaccines; Diphtheria; Diphtheria-Tetanus-Pertussis Vaccine - adverse effects; disease control; Drug Interactions; Female; Fever; Fever - prevention & control; Haemophilus Vaccines - adverse effects; Hemagglutinins; Hepatitis; Hepatitis B Vaccines - adverse effects; Hepatitis B virus; Humans; Ibuprofen; Ibuprofen - administration & dosage; Immune response; Immunogenicity; Immunoglobulin G; Infant; Infants; Male; Nonsteroidal anti-inflammatory drugs; Opsonin Proteins - blood; Paracetamol; Pediatrics; Pertussis; Phagocytosis; Pneumococcal conjugate vaccine; Pneumococcal Vaccines - administration & dosage; Pneumococcal Vaccines - adverse effects; Pneumococcal Vaccines - immunology; Poliovirus Vaccine, Inactivated - adverse effects; Prophylaxis; Serotypes; Streptococcus infections; Streptococcus pneumoniae; Tetanus; vaccination; Vaccines; Vaccines, Combined - adverse effects; Whooping cough; LLOQ; OPA; Pneumococcal conjugate vaccine; PCV; PCV13; Immune response; AE; IgG; Infant; GMR; mITT; GMT; Paracetamol; SAE; DTaP/HBV/IPV/Hib; Ibuprofen; Antipyretic; GMC; FHA; geometric mean concentration; diphtheria-tetanus-acellular pertussis, hepatitis B, inactivated poliovirus, and H influenzae type b (INFANRIX ® hexa); geometric mean titer; serious adverse event; pneumococcal conjugate vaccine; immunoglobulin G; lower limit of quantitation; opsonophagocytic activity; adverse event; geometric mean ratio; 13-valent pneumococcal conjugate vaccine; modified intent to treat; filamentous hemagglutinin