Health-related quality of life in patients with chronic fatigue syndrome: An international study

Objective: Chronic fatigue syndrome (CFS) has been reported worldwide. Our objectives were to determine if patients from different countries have similar profiles of impairments. Methods: Health-related quality of life (HRQoL) was assessed in 740 CFS patients in the US, 82 in the UK, and 65 in Germa...

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Published inJournal of psychosomatic research Vol. 51; no. 2; pp. 431 - 434
Main Authors Hardt, J, Buchwald, D, Wilks, D, Sharpe, M, Nix, W.A, Egle, U.T
Format Journal Article
LanguageEnglish
Published England Elsevier Inc 01.08.2001
Subjects
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ISSN0022-3999
1879-1360
DOI10.1016/S0022-3999(01)00220-3

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Abstract Objective: Chronic fatigue syndrome (CFS) has been reported worldwide. Our objectives were to determine if patients from different countries have similar profiles of impairments. Methods: Health-related quality of life (HRQoL) was assessed in 740 CFS patients in the US, 82 in the UK, and 65 in Germany using the eight subscales of the Short-Form General Health Survey (SF-36). To examine the internal structure, factor analyses were performed. Results: Overall, there was a remarkable similarity in HRQoL among all CFS patients, regardless of location. Patients scored two to three standard deviations below normal on six subscales and one standard deviation below normal on the other two subscales. Factor analysis suggested a two-factor model where the same six subscales constitute the first factor and the two others the second factor. Conclusion: HRQoL is poor in CFS patients from three countries. This study is a first step towards conducting further comparative cross-cultural and international studies.
AbstractList Chronic fatigue syndrome (CFS) has been reported worldwide. Our objectives were to determine if patients from different countries have similar profiles of impairments.OBJECTIVEChronic fatigue syndrome (CFS) has been reported worldwide. Our objectives were to determine if patients from different countries have similar profiles of impairments.Health-related quality of life (HRQoL) was assessed in 740 CFS patients in the US, 82 in the UK, and 65 in Germany using the eight subscales of the Short-Form General Health Survey (SF-36). To examine the internal structure, factor analyses were performed.METHODSHealth-related quality of life (HRQoL) was assessed in 740 CFS patients in the US, 82 in the UK, and 65 in Germany using the eight subscales of the Short-Form General Health Survey (SF-36). To examine the internal structure, factor analyses were performed.Overall, there was a remarkable similarity in HRQoL among all CFS patients, regardless of location. Patients scored two to three standard deviations below normal on six subscales and one standard deviation below normal on the other two subscales. Factor analysis suggested a two-factor model where the same six subscales constitute the first factor and the two others the second factor.RESULTSOverall, there was a remarkable similarity in HRQoL among all CFS patients, regardless of location. Patients scored two to three standard deviations below normal on six subscales and one standard deviation below normal on the other two subscales. Factor analysis suggested a two-factor model where the same six subscales constitute the first factor and the two others the second factor.HRQoL is poor in CFS patients from three countries. This study is a first step towards conducting further comparative cross-cultural and international studies.CONCLUSIONHRQoL is poor in CFS patients from three countries. This study is a first step towards conducting further comparative cross-cultural and international studies.
Objective: Chronic fatigue syndrome (CFS) has been reported worldwide. Our objectives were to determine if patients from different countries have similar profiles of impairments. Methods: Health-related quality of life (HRQoL) was assessed in 740 CFS patients in the US, 82 in the UK, and 65 in Germany using the eight subscales of the Short-Form General Health Survey (SF-36). To examine the internal structure, factor analyses were performed. Results: Overall, there was a remarkable similarity in HRQoL among all CFS patients, regardless of location. Patients scored two to three standard deviations below normal on six subscales and one standard deviation below normal on the other two subscales. Factor analysis suggested a two-factor model where the same six subscales constitute the first factor and the two others the second factor. Conclusion: HRQoL is poor in CFS patients from three countries. This study is a first step towards conducting further comparative cross-cultural and international studies.
Chronic fatigue syndrome (CFS) has been reported worldwide. Our objectives were to determine if patients from different countries have similar profiles of impairments. Health-related quality of life (HRQoL) was assessed in 740 CFS patients in the US, 82 in the UK, and 65 in Germany using the eight subscales of the Short-Form General Health Survey (SF-36). To examine the internal structure, factor analyses were performed. Overall, there was a remarkable similarity in HRQoL among all CFS patients, regardless of location. Patients scored two to three standard deviations below normal on six subscales and one standard deviation below normal on the other two subscales. Factor analysis suggested a two-factor model where the same six subscales constitute the first factor and the two others the second factor. HRQoL is poor in CFS patients from three countries. This study is a first step towards conducting further comparative cross-cultural and international studies.
Objective: Chronic fatigue syndrome (CFS) has been reported worldwide. Our objectives were to determine if patients from different countries have similar profiles of impairments. Methods: Health-related quality of life (HRQoL) was assessed in 740 CFS patients in the US, 82 in the UK, and 65 in Germany using the eight subscales of the Short-Form General Health Survey (SF- 36). To examine the internal structure, factor analyses were performed. Results: Overall, there was a remarkable similarity in HRQoL among all CFS patients, regardless of location. Patients scored two to three standard deviations below normal on six subscales and one standard deviation below normal on the other two subscales. Factor analysis suggested a two-factor model where the same six subscales constitute the first factor and the two others the second factor. Conclusion: HRQoL is poor in CFS patients from three countries. This study is a first step towards conducting further comparative cross-cultural and international studies.
Chronic fatigue syndrome (CFS) has been reported worldwide. To determine if patients from different countries have similar profiles of impairments, health-related quality of life (HRQoL) was assessed in 740 CFS patients in the USA, 82 in the UK, and 65 in Germany using the 8 subscales of the Short-Form General Health Survey (SF-36). Found that HRQoL was poor in CFS patients from all 3 countries. (Original abstract - amended)
Author Sharpe, M
Nix, W.A
Buchwald, D
Hardt, J
Egle, U.T
Wilks, D
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Keywords Functional status
Chronic fatigue syndrome
Quality of life
SF-36
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Snippet Objective: Chronic fatigue syndrome (CFS) has been reported worldwide. Our objectives were to determine if patients from different countries have similar...
Chronic fatigue syndrome (CFS) has been reported worldwide. Our objectives were to determine if patients from different countries have similar profiles of...
Chronic fatigue syndrome (CFS) has been reported worldwide. To determine if patients from different countries have similar profiles of impairments,...
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SubjectTerms Adolescent
Aged
Chronic fatigue syndrome
Cross-Sectional Studies
Crossnational studies
Factor Analysis, Statistical
Fatigue Syndrome, Chronic - psychology
Female
Functional status
Health
Health Status
Humans
Male
Middle Aged
Patients
Quality of Life
SF-36
Title Health-related quality of life in patients with chronic fatigue syndrome: An international study
URI https://www.clinicalkey.com/#!/content/1-s2.0-S0022399901002203
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