Topoisomerase II as a target for anticancer drugs: When enzymes stop being nice - Fortune, John M.; Osheroff, Neil (Progress in Nucleic Acid Research and Molecular Biology, 2000)
Keywords: Animals; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; Binding Sites; Biochemistry; Biological Evolution; Biophysics; DNA Topoisomerases, Type II - chemistry; DNA Topoisomerases, Type II - metabolism; DNA, Neoplasm - metabolism; Drug Resistance; Enzyme Inhibitors - chemistry; Enzyme Inhibitors - pharmacology; Humans; Isoenzymes - antagonists & inhibitors; Isoenzymes - metabolism; Microbiology (non-medical); Models, Biological; Neoplasms - drug therapy; Neoplasms - metabolism; Substrate Specificity; Topoisomerase II Inhibitors