Trends in Lipids Level and Dyslipidemia among Chinese Adults, 2002-2015
To investigate the trends of lipid profiles and dyslipidemia among Chinese adults from 2002 to 2015. Data were collected from three nationally representative cross-sectional surveys. Fasting venous blood samples were collected and serum lipids were tested by biochemical analysis and enzymatic determ...
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Published in | Biomedical and environmental sciences Vol. 32; no. 8; pp. 559 - 570 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
China
Elsevier B.V
01.08.2019
National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050,China%Central laboratory of Beijing Center for Disease Control and Prevention, Beijing 100013, China%Academy of National Food and Strategic Reserves Administration, Beijing 100037, China |
Subjects | |
Online Access | Get full text |
ISSN | 0895-3988 2214-0190 2214-0190 |
DOI | 10.3967/bes2019.074 |
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Abstract | To investigate the trends of lipid profiles and dyslipidemia among Chinese adults from 2002 to 2015.
Data were collected from three nationally representative cross-sectional surveys. Fasting venous blood samples were collected and serum lipids were tested by biochemical analysis and enzymatic determination. Lipid levels and the prevalence of dyslipidemia among adults were analyzed with complex sampling weighting adjustment for age and gender.
The weighted means of TC, TG, and LDL-c significantly increased linearly from 3.93, 1.12, and 2.12 mmol/L in 2002 to 4.59, 1.41, and 2.78 mmol/L in 2010 and then to 4.63, 1.47, and 2.87 mmol/L in 2015, respectively; by contrast, HDL-c levels decreased significantly from 1.30 mmol/L to 1.26 mmol/L over the same period. Similar trends in mean non-HDL-c and lipid-related ratios were observed. The weighted dyslipidemia prevalence linearly increased; in particular, hypercholesterolemia increased from 1.6% to 5.6% and then to 5.8%, hypertriglyceridemia increased from 5.7% to 13.6% and then to 15.0%, low HDL-c increased from 18.8% to 35.5% and then to 24.9%, and high LDL-c increased from 1.3% to 5.6% and then to 7.2% (P for trend < 0.001).
Dyslipidemia increased among Chinese adults from 2002 to 2015. Development of a comprehensive strategy to decrease lipid levels in this population is urgently required. |
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AbstractList | OBJECTIVE To investigate the trends of lipid profiles and dyslipidemia among Chinese adults from 2002 to 2015. METHODS Data were collected from three nationally representative cross-sectional surveys. Fasting venous blood samples were collected and serum lipids were tested by biochemical analysis and enzymatic determination. Lipid levels and the prevalence of dyslipidemia among adults were analyzed with complex sampling weighting adjustment for age and gender. RESULTS The weighted means of TC, TG, and LDL-c significantly increased linearly from 3.93, 1.12, and 2.12 mmol/L in 2002 to 4.59, 1.41, and 2.78 mmol/L in 2010 and then to 4.63, 1.47, and 2.87 mmol/L in 2015, respectively; by contrast, HDL-c levels decreased significantly from 1.30 mmol/L to 1.26 mmol/L over the same period. Similar trends in mean non-HDL-c and lipid-related ratios were observed. The weighted dyslipidemia prevalence linearly increased; in particular, hypercholesterolemia increased from 1.6% to 5.6% and then to 5.8%, hypertriglyceridemia increased from 5.7% to 13.6% and then to 15.0%, low HDL-c increased from 18.8% to 35.5% and then to 24.9%, and high LDL-c increased from 1.3% to 5.6% and then to 7.2% (P for trend < 0.001). CONCLUSION Dyslipidemia increased among Chinese adults from 2002 to 2015. Development of a comprehensive strategy to decrease lipid levels in this population is urgently required. To investigate the trends of lipid profiles and dyslipidemia among Chinese adults from 2002 to 2015. Data were collected from three nationally representative cross-sectional surveys. Fasting venous blood samples were collected and serum lipids were tested by biochemical analysis and enzymatic determination. Lipid levels and the prevalence of dyslipidemia among adults were analyzed with complex sampling weighting adjustment for age and gender. The weighted means of TC, TG, and LDL-c significantly increased linearly from 3.93, 1.12, and 2.12 mmol/L in 2002 to 4.59, 1.41, and 2.78 mmol/L in 2010 and then to 4.63, 1.47, and 2.87 mmol/L in 2015, respectively; by contrast, HDL-c levels decreased significantly from 1.30 mmol/L to 1.26 mmol/L over the same period. Similar trends in mean non-HDL-c and lipid-related ratios were observed. The weighted dyslipidemia prevalence linearly increased; in particular, hypercholesterolemia increased from 1.6% to 5.6% and then to 5.8%, hypertriglyceridemia increased from 5.7% to 13.6% and then to 15.0%, low HDL-c increased from 18.8% to 35.5% and then to 24.9%, and high LDL-c increased from 1.3% to 5.6% and then to 7.2% (P for trend < 0.001). Dyslipidemia increased among Chinese adults from 2002 to 2015. Development of a comprehensive strategy to decrease lipid levels in this population is urgently required. OBJECTIVE To investigate the trends of lipid profiles and dyslipidemia among Chinese adults from 2002 to 2015. METHODS Data were collected from three nationally representative cross-sectional surveys. Fasting venous blood samples were collected and serum lipids were tested by biochemical analysis and enzymatic determination. Lipid levels and the prevalence of dyslipidemia among adults were analyzed with complex sampling weighting adjustment for age and gender. RESULTS The weighted means of TC, TG, and LDL-c significantly increased linearly from 3.93, 1.12, and 2.12 mmol/L in 2002 to 4.59, 1.41, and 2.78 mmol/L in 2010 and then to 4.63, 1.47, and 2.87 mmol/L in 2015, respectively; by contrast, HDL-c levels decreased significantly from 1.30 mmol/L to 1.26 mmol/L over the same period. Similar trends in mean non-HDL-c and lipid-related ratios were observed. The weighted dyslipidemia prevalence linearly increased; in particular, hypercholesterolemia increased from 1.6% to 5.6% and then to 5.8%, hypertriglyceridemia increased from 5.7% to 13.6% and then to 15.0%, low HDL-c increased from 18.8% to 35.5% and then to 24.9%, and high LDL-c increased from 1.3% to 5.6% and then to 7.2% (P for trend < 0.001). CONCLUSION Dyslipidemia increased among Chinese adults from 2002 to 2015. Development of a comprehensive strategy to decrease lipid levels in this population is urgently required.OBJECTIVE To investigate the trends of lipid profiles and dyslipidemia among Chinese adults from 2002 to 2015. METHODS Data were collected from three nationally representative cross-sectional surveys. Fasting venous blood samples were collected and serum lipids were tested by biochemical analysis and enzymatic determination. Lipid levels and the prevalence of dyslipidemia among adults were analyzed with complex sampling weighting adjustment for age and gender. RESULTS The weighted means of TC, TG, and LDL-c significantly increased linearly from 3.93, 1.12, and 2.12 mmol/L in 2002 to 4.59, 1.41, and 2.78 mmol/L in 2010 and then to 4.63, 1.47, and 2.87 mmol/L in 2015, respectively; by contrast, HDL-c levels decreased significantly from 1.30 mmol/L to 1.26 mmol/L over the same period. Similar trends in mean non-HDL-c and lipid-related ratios were observed. The weighted dyslipidemia prevalence linearly increased; in particular, hypercholesterolemia increased from 1.6% to 5.6% and then to 5.8%, hypertriglyceridemia increased from 5.7% to 13.6% and then to 15.0%, low HDL-c increased from 18.8% to 35.5% and then to 24.9%, and high LDL-c increased from 1.3% to 5.6% and then to 7.2% (P for trend < 0.001). CONCLUSION Dyslipidemia increased among Chinese adults from 2002 to 2015. Development of a comprehensive strategy to decrease lipid levels in this population is urgently required. Objective To investigate the trends of lipid profiles and dyslipidemia among Chinese adults from 2002 to 2015. Methods Data were collected from three nationally representative cross-sectional surveys. Fasting venous blood samples were collected and serum lipids were tested by biochemical analysis and enzymatic determination. Lipid levels and the prevalence of dyslipidemia among adults were analyzed with complex sampling weighting adjustment for age and gender. Results The weighted means of TC, TG, and LDL-c significantly increased linearly from 3.93, 1.12, and 2.12 mmol/L in 2002 to 4.59, 1.41, and 2.78 mmol/L in 2010 and then to 4.63, 1.47, and 2.87 mmol/L in 2015, respectively; by contrast, HDL-c levels decreased significantly from 1.30 mmol/L to 1.26 mmol/L over the same period. Similar trends in mean non-HDL-c and lipid-related ratios were observed. The weighted dyslipidemia prevalence linearly increased; in particular, hypercholesterolemia increased from 1.6% to 5.6% and then to 5.8%, hypertriglyceridemia increased from 5.7% to 13.6% and then to 15.0%, low HDL-c increased from 18.8% to 35.5% and then to 24.9%, and high LDL-c increased from 1.3% to 5.6% and then to 7.2% (P for trend < 0.001). Conclusion Dyslipidemia increased among Chinese adults from 2002 to 2015. Development of a comprehensive strategy to decrease lipid levels in this population is urgently required. |
Author | LI, Yu Qian HE, Li ZHAO, Wen Hua MAN, Qing Qing LI, Hong JIA, Shan Shan ZHANG, Jian SONG, Peng Kun PANG, Shao Jie |
AuthorAffiliation | National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050,China%Central laboratory of Beijing Center for Disease Control and Prevention, Beijing 100013, China%Academy of National Food and Strategic Reserves Administration, Beijing 100037, China |
AuthorAffiliation_xml | – name: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050,China%Central laboratory of Beijing Center for Disease Control and Prevention, Beijing 100013, China%Academy of National Food and Strategic Reserves Administration, Beijing 100037, China |
Author_xml | – sequence: 1 givenname: Peng Kun surname: SONG fullname: SONG, Peng Kun organization: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050,China – sequence: 2 givenname: Qing Qing surname: MAN fullname: MAN, Qing Qing organization: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050,China – sequence: 3 givenname: Hong surname: LI fullname: LI, Hong organization: Central laboratory of Beijing Center for Disease Control and Prevention, Beijing 100013, China – sequence: 4 givenname: Shao Jie surname: PANG fullname: PANG, Shao Jie organization: Academy of National Food and Strategic Reserves Administration, Beijing 100037, China – sequence: 5 givenname: Shan Shan surname: JIA fullname: JIA, Shan Shan organization: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050,China – sequence: 6 givenname: Yu Qian surname: LI fullname: LI, Yu Qian organization: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050,China – sequence: 7 givenname: Li surname: HE fullname: HE, Li organization: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050,China – sequence: 8 givenname: Wen Hua surname: ZHAO fullname: ZHAO, Wen Hua email: zhangjian6708@aliyun.com organization: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050,China – sequence: 9 givenname: Jian surname: ZHANG fullname: ZHANG, Jian email: zhaowh@chinacdc.cn organization: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050,China |
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Keywords | Lipids Adults Cross-sectional study China Dyslipidemia |
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Snippet | To investigate the trends of lipid profiles and dyslipidemia among Chinese adults from 2002 to 2015.
Data were collected from three nationally representative... OBJECTIVE To investigate the trends of lipid profiles and dyslipidemia among Chinese adults from 2002 to 2015. METHODS Data were collected from three... Objective To investigate the trends of lipid profiles and dyslipidemia among Chinese adults from 2002 to 2015. Methods Data were collected from three... |
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SubjectTerms | Adults China Cross-sectional study Dyslipidemia Lipids |
Title | Trends in Lipids Level and Dyslipidemia among Chinese Adults, 2002-2015 |
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