Pharmacological activity of OST-01, a natural product from baccharis coridifolia, on breast cancer cells - Kang, HyunJun; Hoang, Dinh Hoa; Valerio, Melissa; Pathak, Khyatiben; Graff, William; LeVee, Alexis; Wu, Jun; LaBarge, Mark A.; Frankhouser, David; Rockne, Russell C.; Pirrotte, Patrick; Zhang, Bin; et al. (Journal of hematology and oncology, 2025)
Keywords: Animals; Antineoplastic Agents, Phytogenic - pharmacology; Antitumor activity; Apoptosis; BCSC; Biological Products - pharmacology; Biological Products - therapeutic use; Breast cancer; Cancer; Cancer cells; Cancer Research; Cancer therapies; Care and treatment; CD44 antigen; Cell culture; Cell cycle; Cell death; Cell Line, Tumor; Cell proliferation; Cell Proliferation - drug effects; Comparative analysis; Correspondence; Female; Ferroptosis; Ferroptosis - drug effects; Genes; Health aspects; Hematology; Humans; Leukemia; Lipid peroxidation; Medicine; Medicine & Public Health; Metabolism; Mice; Natural product; Natural products; Neoplastic Stem Cells - drug effects; Neoplastic Stem Cells - pathology; Oncology; OST-01; Oxidative stress; Selenoproteins; Stem cells; TNBC; Toxicity; Triple Negative Breast Neoplasms - drug therapy; Triple Negative Breast Neoplasms - pathology; Tumors; Vimentin; Xenograft Model Antitumor Assays; Natural product; OST-01; Ferroptosis; TNBC; BCSC