Muscular dystrophy-associated SUN1 and SUN2 variants disrupt nuclear-cytoskeletal connections and myonuclear organization - Meinke, Peter; Mattioli, Elisabetta; Haque, Farhana; Antoku, Susumu; Columbaro, Marta; Straatman, Kees R; Worman, Howard J; Gundersen, Gregg G; Lattanzi, Giovanna; Wehnert, Manfred; Shackleton, Sue (PLoS genetics, 2014)
Keywords: Animals; Biology and Life Sciences; Cardiomyopathy; Cell Nucleus - genetics; Cell Nucleus - metabolism; Cells, Cultured; Cytoskeleton - genetics; Cytoskeleton - metabolism; Cytoskeleton - pathology; Defects; Disease; Experiments; Female; Fibroblasts - metabolism; Fibroblasts - pathology; Gene expression; Humans; Intracellular Signaling Peptides and Proteins - genetics; Intracellular Signaling Peptides and Proteins - metabolism; Male; Medicine and Health Sciences; Membrane Proteins - genetics; Membrane Proteins - metabolism; Mice; Microtubule-Associated Proteins - genetics; Microtubule-Associated Proteins - metabolism; Muscle Fibers, Skeletal - metabolism; Muscle Fibers, Skeletal - pathology; Muscular Dystrophies - genetics; Muscular Dystrophies - metabolism; Muscular Dystrophies - pathology; Muscular dystrophy; Mutation; Mutation - genetics; Myoblasts - metabolism; Myoblasts - pathology; NIH 3T3 Cells; Nuclear Envelope - genetics; Nuclear Envelope - metabolism; Nuclear Envelope - pathology; Nuclear Proteins - genetics; Nuclear Proteins - metabolism; Pathogenesis; Patients; Proteins