Towards a reduced order model of the periodontal ligament

• Published in: Scientific reports Vol. 15; no. 1; pp. 5779 - 18
• Main Authors: Kaiser, Albert Heinrich, Bourauel, Christoph
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 17.02.2025; Nature Publishing Group; Nature Portfolio
• Subjects: 639/705; 692/308; Alveolar bone; Animals; Biomechanical Phenomena; Compressibility; Computer Simulation; Dimensionless analysis; Elasticity; Fluid flow; Humanities and Social Sciences; Ligaments; Load distribution; Membrane permeability; Models, Biological; multidisciplinary; Orthodontic tooth movement (OTM); Orthodontics; Parameter identification; Periodontal ligament; Periodontal ligament (PDL); Periodontal Ligament - physiology; Periodontium; Poro-visco-hyperelastic model; Premolars; Reduced order model; Science; Science (multidisciplinary); Simulation; Stress, Mechanical; Swine; Teeth; Test and simulation; Tooth Movement Techniques; Vascular system; Viscoelasticity; Poro-visco-hyperelastic model; Test and simulation; Periodontal ligament (PDL); Dimensionless analysis; Orthodontic tooth movement (OTM); Reduced order model
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-025-88767-x

Based on previous in vitro experiments with specimens of porcine mandibular premolars, the simulation of the periodontal ligament response to force in the initial phase of orthodontic tooth movement is described. The initial response of the periodontal ligament can be simulated with a poro-visco-hyperelastic model. For the ground substance a hyperelastic constitutive model for compressible material was used. To facilitate parameter identification a reduced order model and an optimal interpolation metamodel were used. Parameters for the constitutive model identified herein are in good agreement with published values. They indicate a high initial compressibility of the periodontal ligament, which may be attributed to the compressibility of the vascular system within the periodontal ligament. Dimensionless analysis suggests that poroelastic behaviour will gradually cease when viscoelastic relaxation progresses. This was observed as well in the simulation and confirmed by varying the poroelastic model parameters within physically justified limits. Alveolar bone permeability has a significant influence on the flow of pore fluid in the periodontium due to poroelasticity. It is argued that in vivo alveolar bone perforation may adapt locally to optimise for the predominant load situation. A strain rate hardening effect was observed, which is not covered by the simulation, and may be the subject of further investigations.