Different characteristics of quality of life in celiac disease patients

To study quality of life (QoL) in patients with celiac disease (CD) in the course of treatment with aglutenic diet (AD). Modern algorithm of glutenic enteropathy diagnosis (enzyme immunoassay, histological examination of the biopsy of distal duodenum mucosa) was used in 650 patients with different g...

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Bibliographic Details
Published inTerapevtic̆eskii arhiv Vol. 83; no. 2; pp. 25 - 28
Main Authors Moiseenko, E E, Osipenko, M F, Ageeva, T A, Krotov, S A, Burbik, N N
Format Journal Article
LanguageRussian
Published Russia (Federation) "Consilium Medicum" Publishing house 01.01.2011
Subjects
Adolescent
Adult
aglutenic diet
celiac disease
Celiac Disease - diet therapy
Celiac Disease - psychology
Diet, Gluten-Free
Female
Humans
Male
Middle Aged
Prognosis
Quality of Life
Surveys and Questionnaires
Young Adult
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ISSN0040-3660
2309-5342

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Summary:To study quality of life (QoL) in patients with celiac disease (CD) in the course of treatment with aglutenic diet (AD). Modern algorithm of glutenic enteropathy diagnosis (enzyme immunoassay, histological examination of the biopsy of distal duodenum mucosa) was used in 650 patients with different gastrointestinal symptoms. QoL was assessed in the course of AD treatment of CD with application of universal standard questionnaire MOS SF-36. CD was diagnosed in 56 (8.6%) patients. Classic CD was diagnosed in 44 (78.6%) patients, atypical CD--in 12 (21.4%). Significant lowering of QoL characteristic psychological health" was observed in CD patients under 30 and over 50 and "physical health" in 30-50-year-old CD patients. Women had low points on "mental health" scale. After 3 AD months QoL worsened by all the scales, but after 12 months QoL significantly improved. QoL in patients with classic CD is associated with gender and age. First, AD deteriorates QoL, but 1-year diet therapy improves QoL.
ISSN:0040-3660
2309-5342