The Graft Infusion Technique (GIT) for Treatment of Peri-Implantitis Defects: Case Series
Peri-implantitis is a site-specific infectious disease that causes an inflammatory process in soft tissues, and bone loss around an osseointegrated implant in function. Several techniques with non-surgical or surgical debridement and decontamination followed by ongoing supportive therapy or regenera...
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| Published in | Journal of dentistry (Shiraz) Vol. 22; no. 4; pp. 296 - 303 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
Iran
Shiraz University of Medical Sciences
01.12.2021
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| Subjects | |
| Online Access | Get full text |
| ISSN | 2345-6485 2345-6418 |
| DOI | 10.30476/DENTJODS.2021.86658.1203 |
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| Abstract | Peri-implantitis is a site-specific infectious disease that causes an inflammatory process in soft tissues, and bone loss around an osseointegrated implant in function. Several techniques with non-surgical or surgical debridement and decontamination followed by ongoing supportive therapy or regeneration of the peri-implant bone defects have been proposed in the literature. However, the literature is still unclear on an effective protocol for implant surface decontamination or the appropriate choice of regenerative materials. This case series describes a surgical technique to treat peri-implantitis osseous defects using a mixture of deproteinized bovine bone mineral with 10% porcine collagen (DBBM-C) in a block form, soaked in an appropriate antibiotic. The use of this combination provides advantages such as good graft adaptability along with localized antibiotic release without the use of systemic antibiotics. Thus, this technique might be an effective method to treat amenable peri-implantitis defects. Additionally, the proposed algorithm also allows for customized culture based antibiotic loading. To the best of the authors' knowledge, this is the first case series documenting this technique for peri-implantitis defects. Long-term studies with controlled samples would be necessary for further evaluation. |
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| AbstractList | Peri-implantitis is a site-specific infectious disease that causes an inflammatory process in soft tissues, and bone loss around an osseointegrated implant in function. Several techniques with non-surgical or surgical debridement and decontamination followed by ongoing supportive therapy or regeneration of the peri-implant bone defects have been proposed in the literature. However, the literature is still unclear on an effective protocol for implant surface decontamination or the appropriate choice of regenerative materials. This case series describes a surgical technique to treat peri-implantitis osseous defects using a mixture of deproteinized bovine bone mineral with 10% porcine collagen (DBBM-C) in a block form, soaked in an appropriate antibiotic. The use of this combination provides advantages such as good graft adaptability along with localized antibiotic release without the use of systemic antibiotics. Thus, this technique might be an effective method to treat amenable peri-implantitis defects. Additionally, the proposed algorithm also allows for customized culture based antibiotic loading. To the best of the authors' knowledge, this is the first case series documenting this technique for peri-implantitis defects. Long-term studies with controlled samples would be necessary for further evaluation. Peri-implantitis is a site-specific infectious disease that causes an inflammatory process in soft tissues, and bone loss around an osseointegrated implant in function. Several techniques with non‐surgical or surgical debridement and decontamination followed by ongoing supportive therapy or regeneration of the peri‐implant bone defects have been proposed in the literature. However, the literature is still unclear on an effective protocol for implant surface decontamination or the appropriate choice of regenerative materials. This case series describes a surgical technique to treat peri-implantitis osseous defects using a mixture of deproteinized bovine bone mineral with 10% porcine collagen (DBBM-C) in a block form, soaked in an appropriate antibiotic. The use of this combination provides advantages such as good graft adaptability along with localized antibiotic release without the use of systemic antibiotics. Thus, this technique might be an effective method to treat amenable peri-implantitis defects. Additionally, the proposed algorithm also allows for customized culture based antibiotic loading. To the best of the authors’ knowledge, this is the first case series documenting this technique for peri-implantitis defects. Long-term studies with controlled samples would be necessary for further evaluation. Peri-implantitis is a site-specific infectious disease that causes an inflammatory process in soft tissues, and bone loss around an osseointegrated implant in function. Several techniques with non-surgical or surgical debridement and decontamination followed by ongoing supportive therapy or regeneration of the peri-implant bone defects have been proposed in the literature. However, the literature is still unclear on an effective protocol for implant surface decontamination or the appropriate choice of regenerative materials. This case series describes a surgical technique to treat peri-implantitis osseous defects using a mixture of deproteinized bovine bone mineral with 10% porcine collagen (DBBM-C) in a block form, soaked in an appropriate antibiotic. The use of this combination provides advantages such as good graft adaptability along with localized antibiotic release without the use of systemic antibiotics. Thus, this technique might be an effective method to treat amenable peri-implantitis defects. Additionally, the proposed algorithm also allows for customized culture based antibiotic loading. To the best of the authors' knowledge, this is the first case series documenting this technique for peri-implantitis defects. Long-term studies with controlled samples would be necessary for further evaluation.Peri-implantitis is a site-specific infectious disease that causes an inflammatory process in soft tissues, and bone loss around an osseointegrated implant in function. Several techniques with non-surgical or surgical debridement and decontamination followed by ongoing supportive therapy or regeneration of the peri-implant bone defects have been proposed in the literature. However, the literature is still unclear on an effective protocol for implant surface decontamination or the appropriate choice of regenerative materials. This case series describes a surgical technique to treat peri-implantitis osseous defects using a mixture of deproteinized bovine bone mineral with 10% porcine collagen (DBBM-C) in a block form, soaked in an appropriate antibiotic. The use of this combination provides advantages such as good graft adaptability along with localized antibiotic release without the use of systemic antibiotics. Thus, this technique might be an effective method to treat amenable peri-implantitis defects. Additionally, the proposed algorithm also allows for customized culture based antibiotic loading. To the best of the authors' knowledge, this is the first case series documenting this technique for peri-implantitis defects. Long-term studies with controlled samples would be necessary for further evaluation. |
| Author | Bhatavadekar, Neel B Gharpure, Amit S |
| AuthorAffiliation | 1 Private Practice, Clarus Dental Specialities, Pune, India. Adjunct Faculty, University of North Carolina at Chapel Hill, NC, Adjunct Faculty, University of Texas Health Science Center, Houston, TX, Adjunct Faculty, Bioengineering Department, Rice University, FL 2 Graduate Periodontics, University of Washington School of Dentistry, Seattle, WA |
| AuthorAffiliation_xml | – name: 2 Graduate Periodontics, University of Washington School of Dentistry, Seattle, WA – name: 1 Private Practice, Clarus Dental Specialities, Pune, India. Adjunct Faculty, University of North Carolina at Chapel Hill, NC, Adjunct Faculty, University of Texas Health Science Center, Houston, TX, Adjunct Faculty, Bioengineering Department, Rice University, FL |
| Author_xml | – sequence: 1 givenname: Neel B surname: Bhatavadekar fullname: Bhatavadekar, Neel B organization: Private Practice, Clarus Dental Specialities, Pune, India. Adjunct Faculty, University of North Carolina at Chapel Hill, NC, Adjunct Faculty, University of Texas Health Science Center, Houston, TX, Adjunct Faculty, Bioengineering Department, Rice University, FL – sequence: 2 givenname: Amit S surname: Gharpure fullname: Gharpure, Amit S organization: Graduate Periodontics, University of Washington School of Dentistry, Seattle, WA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34904127$$D View this record in MEDLINE/PubMed |
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| Keywords | Deproteinized bovine bone mineral with 10% collagen Peri-implantitis Bone Grafting Radiographs Dental Implants Survival Surgical Procedures Reconstructive Surgical Procedures Success |
| Language | English |
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| SubjectTerms | Case Series dental implants; bone grafting; peri-implantitis; radiographs; surgical procedures; reconstructive surgical procedures; deproteinized bovine bone mineral with 10% collagen; success; survival |
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| Title | The Graft Infusion Technique (GIT) for Treatment of Peri-Implantitis Defects: Case Series |
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