Characteristics of adults with Down syndrome hospitalized in Spanish internal medicine departments during 2005–2014
The clinical problems of adults with Down syndrome (DS) seem to differ from those of the general population. To better understand these differences, we list the demographic and clinical characteristics of adults with DS admitted to Spanish internal medicine departments during 2005–2014. We conducted...
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Published in | Revista clínica espanõla (English edition) Vol. 220; no. 9; pp. 553 - 560 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Elsevier España, S.L.U
01.12.2020
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Subjects | |
Online Access | Get full text |
ISSN | 2254-8874 2254-8874 |
DOI | 10.1016/j.rceng.2019.11.003 |
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Abstract | The clinical problems of adults with Down syndrome (DS) seem to differ from those of the general population. To better understand these differences, we list the demographic and clinical characteristics of adults with DS admitted to Spanish internal medicine departments during 2005–2014.
We conducted an observational retrospective study using data collected from the minimum basic data set on hospitalisation episodes of adults with DS in the internal medicine departments of Spain’s National Health System from 2005 to 2014. We analysed the patients’ epidemiological, clinical and societal data.
A total of 7548 hospitalisation episodes from 3786 patients were recorded. Some 56.6% of the patients were male with a mean age (±SD) of 47 ± 13 years, and 715 of the patients died (18.9%). The age-adjusted mortality was 26.6%, and the mean stay was 9.6 ± 12 days. The hospitalisation was for respiratory disease in 3684 episodes (48.8%) and for cardiac origin in 760 (10%). The most common comorbidities were hypothyroidism (27.1%, 2043 episodes), epilepsy (24.1%, 1819 episodes) and dementia (15.4%, 1162 episodes).
The hospitalisation of adults with DS in internal medicine departments has increased in the past decade. Although the reasons for hospitalisation, mean stay and cost per episode for this population are similar to those of the general population treated by internal medicine departments, the age-adjusted hospital mortality was significantly greater.
Los problemas clínicos de los adultos con síndrome de Down (SD) parecen diferir de los de la población general. Para entender mejor estas diferencias describimos las características demográficas y clínicas de los adultos con SD que ingresaron en los servicios de Medicina Interna españoles en el periodo de 2005–2014.
Estudio observacional retrospectivo sobre datos recogidos en el conjunto mínimo básico de datos (CMBD) de los episodios de ingreso de adultos con SD en los servicios de Medicina Interna del Sistema Nacional de Salud desde 2005 a 2014. Se analizaron variables epidemiológicas, clínicas y sociales.
Se registraron 7.548 episodios de ingreso de 3.786 pacientes. El 56,6% eran varones con una edad media (± DE) de 47 ± 13 años. Fallecieron 715 pacientes (18,9%). La mortalidad ajustada a la edad fue 26,6% y su estancia media fue de 9,6 ± 12 días. En 3.684 episodios (48,8%) el ingreso fue por patología respiratoria y en 760 (10%), de origen cardiológico. Las comorbilidades más frecuentes fueron el hipotiroidismo (27,1%, 2.043 episodios), la epilepsia (24.1%, 1.819 episodios) y la demencia (15.4%, 1.162 episodios).
Los ingresos de adultos con SD en los servicios de Medicina Interna han aumentado en la última década. Si bien los motivos de ingreso, estancia media y coste por episodio de esta población son similares a los de la población general atendida en Medicina Interna, la mortalidad intrahospitalaria ajustada por edad fue significativamente mayor. |
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AbstractList | The clinical problems of adults with Down syndrome (DS) seem to differ from those of the general population. To better understand these differences, we list the demographic and clinical characteristics of adults with DS admitted to Spanish internal medicine departments during 2005–2014.
We conducted an observational retrospective study using data collected from the minimum basic data set on hospitalisation episodes of adults with DS in the internal medicine departments of Spain’s National Health System from 2005 to 2014. We analysed the patients’ epidemiological, clinical and societal data.
A total of 7548 hospitalisation episodes from 3786 patients were recorded. Some 56.6% of the patients were male with a mean age (±SD) of 47 ± 13 years, and 715 of the patients died (18.9%). The age-adjusted mortality was 26.6%, and the mean stay was 9.6 ± 12 days. The hospitalisation was for respiratory disease in 3684 episodes (48.8%) and for cardiac origin in 760 (10%). The most common comorbidities were hypothyroidism (27.1%, 2043 episodes), epilepsy (24.1%, 1819 episodes) and dementia (15.4%, 1162 episodes).
The hospitalisation of adults with DS in internal medicine departments has increased in the past decade. Although the reasons for hospitalisation, mean stay and cost per episode for this population are similar to those of the general population treated by internal medicine departments, the age-adjusted hospital mortality was significantly greater.
Los problemas clínicos de los adultos con síndrome de Down (SD) parecen diferir de los de la población general. Para entender mejor estas diferencias describimos las características demográficas y clínicas de los adultos con SD que ingresaron en los servicios de Medicina Interna españoles en el periodo de 2005–2014.
Estudio observacional retrospectivo sobre datos recogidos en el conjunto mínimo básico de datos (CMBD) de los episodios de ingreso de adultos con SD en los servicios de Medicina Interna del Sistema Nacional de Salud desde 2005 a 2014. Se analizaron variables epidemiológicas, clínicas y sociales.
Se registraron 7.548 episodios de ingreso de 3.786 pacientes. El 56,6% eran varones con una edad media (± DE) de 47 ± 13 años. Fallecieron 715 pacientes (18,9%). La mortalidad ajustada a la edad fue 26,6% y su estancia media fue de 9,6 ± 12 días. En 3.684 episodios (48,8%) el ingreso fue por patología respiratoria y en 760 (10%), de origen cardiológico. Las comorbilidades más frecuentes fueron el hipotiroidismo (27,1%, 2.043 episodios), la epilepsia (24.1%, 1.819 episodios) y la demencia (15.4%, 1.162 episodios).
Los ingresos de adultos con SD en los servicios de Medicina Interna han aumentado en la última década. Si bien los motivos de ingreso, estancia media y coste por episodio de esta población son similares a los de la población general atendida en Medicina Interna, la mortalidad intrahospitalaria ajustada por edad fue significativamente mayor. |
Author | Moldenhauer, F. Real de Asúa, D. Barba, R. Aparicio, P. Suárez, C. |
Author_xml | – sequence: 1 givenname: P. surname: Aparicio fullname: Aparicio, P. email: papariciojimenez@gmail.com organization: Servicio de Medicina Interna, Hospital Universitario Clínico San Carlos, Madrid, Spain – sequence: 2 givenname: R. surname: Barba fullname: Barba, R. organization: Servicio de Medicina Interna, Hospital Universitario Rey Juan Carlos, Móstoles, Madrid, Spain – sequence: 3 givenname: F. surname: Moldenhauer fullname: Moldenhauer, F. organization: Servicio de Medicina Interna, Hospital Universitario de la Princesa, Madrid, Spain – sequence: 4 givenname: C. surname: Suárez fullname: Suárez, C. organization: Servicio de Medicina Interna, Hospital Universitario de la Princesa, Madrid, Spain – sequence: 5 givenname: D. surname: Real de Asúa fullname: Real de Asúa, D. organization: Servicio de Medicina Interna, Hospital Universitario de la Princesa, Madrid, Spain |
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Snippet | The clinical problems of adults with Down syndrome (DS) seem to differ from those of the general population. To better understand these differences, we list... |
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Title | Characteristics of adults with Down syndrome hospitalized in Spanish internal medicine departments during 2005–2014 |
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