PAX5 is part of a functional transcription factor network targeted in lymphoid leukemia - Okuyama, Kazuki; Strid, Tobias; Kuruvilla, Jacob; Somasundaram, Rajesh; Cristobal, Susana; Smith, Emma; Prasad, Mahadesh; Fioretos, Thoas; Lilljebjörn, Henrik; Soneji, Shamit; Lang, Stefan; Ungerbäck, Jonas; et al. (PLoS genetics, 2019)
Keywords: Acute myeloid leukemia; AML1 protein; Animal models; Animals; B cells; Basic Medicine; Bioinformatics; Biology and life sciences; Chromosomes; Collaboration; Core Binding Factor Alpha 2 Subunit - genetics; Disease Models, Animal; Displays (Marketing); DNA binding proteins; Funding; Fusion protein; Gene expression; Gene Expression Regulation; Gene Expression Regulation, Leukemic; Gene Regulatory Networks - genetics; Genes; Genetic aspects; Genetics; Genomes; Health aspects; Hematology; Humans; Ikaros Transcription Factor - genetics; Karyotypes; Leukemia; Lymphatic leukemia; Lymphocytes B; Lymphocytic leukemia; Malignancy; Medical and Health Sciences; Medical Genetics and Genomics (including Gene Therapy); Medicin och hälsovetenskap; Medicine; Medicine and Health Sciences; Medicinsk genetik och genomik (Här ingår: Genterapi); Medicinska och farmaceutiska grundvetenskaper; Mice; Mice, Knockout; Mutation; Oncogene Proteins, Fusion - genetics; Pax5 protein; PAX5 Transcription Factor - genetics; Pipelines; Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology; Precursor Cells, B-Lymphoid; Primary Cell Culture; Proteins; Research and Analysis Methods; Runx1 protein; Software; Stem cells; Supervision; Technology; Transcription factors; Tumor Cells, Cultured; Sweden