Transmission of Single HIV-1 Genomes and Dynamics of Early Immune Escape Revealed by Ultra-Deep Sequencing - Fischer, Will; Ganusov, Vitaly V.; Giorgi, Elena E.; Hraber, Peter T.; Keele, Brandon F.; Leitner, Thomas; Han, Cliff S.; Gleasner, Cheryl D.; Green, Lance; Lo, Chien-Chi; Nag, Ambarish; Wallstrom, Timothy C.; et al. (PloS one, 2010)
Keywords: Amino acids; Analysis; Antigenic determinants; BASIC BIOLOGICAL SCIENCES; Biology; CD8 antigen; Computational Biology/Comparative Sequence Analysis; Computational Biology/Evolutionary Modeling; Computational Biology/Macromolecular Sequence Analysis; Consensus Sequence; Containment; Disease transmission; Epitopes; Epitopes - genetics; Epitopes - immunology; Evolution; Evolution, Molecular; Evolutionary Biology/Microbial Evolution and Genomics; Fitness; Gene sequencing; Genome, Viral - genetics; Genomes; Genomics; Health aspects; HIV; HIV Infections - immunology; HIV-1 - genetics; HIV-1 - immunology; HIV-1 - physiology; Human immunodeficiency virus; Human immunodeficiency virus 1; Humans; Immune evasion; Immune Evasion - genetics; immune response; Immunology/Immune Response; Immunology/Immunity to Infections; Infection; Infections; Lymphocytes; Lymphocytes T; Medical research; Medicine; microbial mutation; Mutation; natural selection; phylogenetic analysis; Phylogenetics; polymerase chain reaction; Pressure; Public Health and Epidemiology/Infectious Diseases; Reproductive fitness; Reversion; Sampling; Selection, Genetic; Sequence Analysis, DNA; T cells; Time Factors; viral load; viral replication; Viremia; Virology/Host Antiviral Responses; Virology/Immune Evasion; Virology/Immunodeficiency Viruses; Virology/Vaccines; Virology/Virus Evolution and Symbiosis; Virus diseases; Viruses; Alabama; New Mexico; United States--US; Massachusetts