Pharmacokinetic Study of Adjuvant Gemcitabine Therapy for Biliary Tract Cancer following Major Hepatectomy (KHBO1101) - Fujiwara, Yutaka; Kobayashi, Shogo; Nagano, Hiroaki; Kanai, Masashi; Hatano, Etsuo; Toyoda, Masanori; Ajiki, Tetsuo; Takashima, Yuki; Yoshimura, Kenichi; Hamada, Akinobu; Minami, Hironobu; Ioka, Tatsuya (PloS one, 2015)
Keywords: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic - pharmacokinetics; Antimetabolites, Antineoplastic - therapeutic use; Biliary tract; Biliary tract cancer; Biliary Tract Neoplasms - drug therapy; Biliary Tract Neoplasms - surgery; Bone marrow; Cancer; Cancer therapies; Care and treatment; Chemotherapy; Chemotherapy, Adjuvant; Cholangiocarcinoma; Cholangiocarcinoma - drug therapy; Cholangiocarcinoma - surgery; Chromatography; Combined Modality Therapy; Complications and side effects; Deoxycytidine - analogs & derivatives; Deoxycytidine - pharmacokinetics; Deoxycytidine - therapeutic use; Dosage and administration; Dose-Response Relationship, Drug; Drug dosages; Drug therapy; Female; Gemcitabine; Health aspects; Hematology; Hepatectomy; Hospitals; Humans; Intravenous administration; Intravenous infusion; Leukopenia; Liver; Male; Medicine; Metabolites; Middle Aged; Myelosuppression; Neutropenia; Oncology; Patients; Pharmacodynamics; Pharmacokinetics; Pharmacology; Quality; Surgery; Therapy; Thrombocytopenia; Toxicity; Treatment Outcome; University graduates; Japan