dnc-1/dynactin 1 Knockdown Disrupts Transport of Autophagosomes and Induces Motor Neuron Degeneration - Ikenaka, Kensuke; Kawai, Kaori; Katsuno, Masahisa; Huang, Zhe; Jiang, Yue-Mei; Iguchi, Yohei; Kobayashi, Kyogo; Kimata, Tsubasa; Waza, Masahiro; Tanaka, Fumiaki; Mori, Ikue; Sobue, Gen (PloS one, 2013)
Keywords: Alzheimer's disease; Amyotrophic lateral sclerosis; Animals; Autophagy; Axonal transport; Biology; Caenorhabditis elegans; Caenorhabditis elegans - genetics; Caenorhabditis elegans - physiology; Caenorhabditis elegans Proteins - genetics; Caenorhabditis elegans Proteins - physiology; Cell death; Defects; Degeneration; Dynactin; Dynactin Complex; Dynein; Gene expression; Health aspects; Homology; Humans; Huntingtons disease; Immunohistochemistry; In Situ Hybridization; Kinases; Medicine; Microscopy, Electron; Microtubule-Associated Proteins - genetics; Microtubule-Associated Proteins - physiology; Models, Biological; Motor neurone disease; Motor neurons; Motor Neurons - pathology; Mutation; Nervous system diseases; Neurobiology; Neurodegeneration; Neurology; Neurons; Neurosciences; Organelles; Phagocytosis; Phagosomes; Phagosomes - metabolism; Physiological aspects; Protein transport; Proteins; Rapamycin; Retrograde transport; Rodents; Science; Transport; University graduates; Japan