Orexin neurons suppress narcolepsy via 2 distinct efferent pathways - Hasegawa, Emi; Yanagisawa, Masashi; Sakurai, Takeshi; Mieda, Michihiro (The Journal of clinical investigation, 2014)
Keywords: Animals; Biomedical research; Brain - metabolism; Care and treatment; Clozapine - analogs & derivatives; Clozapine - chemistry; Dependovirus - chemistry; Designer Drugs - chemistry; Development and progression; Efferent pathways; Efferent Pathways - drug effects; Efferent Pathways - metabolism; Electroencephalography; Electromyography; Genotype & phenotype; Grants; Green Fluorescent Proteins - metabolism; Intracellular Signaling Peptides and Proteins - metabolism; Locus Coeruleus - metabolism; Male; Medical research; Mice; Mice, Inbred C57BL; Narcolepsy; Narcolepsy - drug therapy; Narcolepsy - metabolism; Narcolepsy - physiopathology; Neurons; Neurons, Efferent - drug effects; Neurons, Efferent - metabolism; Neuropeptides; Neuropeptides - metabolism; Neurotransmitters; Orexin Receptors - genetics; Orexins; Phenotype; Raphe Nuclei - pathology; Signal Transduction; Sleep; Wakefulness