丘脑底核磁共振成像技术研究进展
丘脑底核（subthalamic nucleus,STN）是我国帕金森病患者接受脑深部电刺激（deep brain stimulation,DBS）治疗的主要核团。磁共振（MRI）影像个体化、精确植入电极至STN的感觉运动部要求MRI成像对STN边界清晰划分,并确保图像保真。目前使用的MRI序列可分为3大类:基于自旋回波序列的T2加权成像、反转恢复序列、扩散张量成像、各向异性分数;基于磁化转移技术的磁敏感加权成像、自由衰减的T2*成像等;基于磁敏感图像重建技术的定量磁敏感图谱。其中,定量磁敏感图谱的STN与周边的信噪比最优、边界最清晰,T2*技术次之;T2加权成像在患者戴框架时几何精度较高,适...
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| Published in | 中国临床医学 Vol. 24; no. 6; pp. 868 - 872 |
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| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
海军军医大学学员旅,上海,200433%海军军医大学附属长海医院影像科,上海,200433%海军军医大学海医系,上海,200433%海军军医大学附属长海医院神经外科,上海,200433
2017
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1008-6358 |
| DOI | 10.12025/j.issn.1008-6358.2017.20170502 |
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| Abstract | 丘脑底核（subthalamic nucleus,STN）是我国帕金森病患者接受脑深部电刺激（deep brain stimulation,DBS）治疗的主要核团。磁共振（MRI）影像个体化、精确植入电极至STN的感觉运动部要求MRI成像对STN边界清晰划分,并确保图像保真。目前使用的MRI序列可分为3大类:基于自旋回波序列的T2加权成像、反转恢复序列、扩散张量成像、各向异性分数;基于磁化转移技术的磁敏感加权成像、自由衰减的T2*成像等;基于磁敏感图像重建技术的定量磁敏感图谱。其中,定量磁敏感图谱的STN与周边的信噪比最优、边界最清晰,T2*技术次之;T2加权成像在患者戴框架时几何精度较高,适合戴框架直接定位使用。 |
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| AbstractList | R742; 丘脑底核(subthalamic nucleus,STN)是我国帕金森病患者接受脑深部电刺激(deep brain stimulation,DBS)治疗的主要核团.磁共振(MRI)影像个体化、精确植入电极至STN的感觉运动部要求MRI成像对STN边界清晰划分,并确保图像保真.目前使用的MRI序列可分为3大类:基于自旋回波序列的T2加权成像、反转恢复序列、扩散张量成像、各向异性分数;基于磁化转移技术的磁敏感加权成像、自由衰减的T2*成像等;基于磁敏感图像重建技术的定量磁敏感图谱.其中,定量磁敏感图谱的STN与周边的信噪比最优、边界最清晰,T2*技术次之;T2加权成像在患者戴框架时几何精度较高,适合戴框架直接定位使用. 丘脑底核（subthalamic nucleus,STN）是我国帕金森病患者接受脑深部电刺激（deep brain stimulation,DBS）治疗的主要核团。磁共振（MRI）影像个体化、精确植入电极至STN的感觉运动部要求MRI成像对STN边界清晰划分,并确保图像保真。目前使用的MRI序列可分为3大类:基于自旋回波序列的T2加权成像、反转恢复序列、扩散张量成像、各向异性分数;基于磁化转移技术的磁敏感加权成像、自由衰减的T2*成像等;基于磁敏感图像重建技术的定量磁敏感图谱。其中,定量磁敏感图谱的STN与周边的信噪比最优、边界最清晰,T2*技术次之;T2加权成像在患者戴框架时几何精度较高,适合戴框架直接定位使用。 |
| Abstract_FL | Subthalamic nucleus (STN) is the main target nucleus for deep brain stimulation (DBS) treatment in patients with Parkinson disease.To implant the electrode on the sensorimotor part of STN individually and accurately,the boundary of STN is required to be clarified clearly on the magnetic resonance imaging (MRI) without geometric distortion.At present,there are three categories of MRI sequences:spin echo sequence including T2-weighted imaging (T2WI),inversion recovery (IR),diffusion tensor imaging (DTI),and fractional anisotropy (FA);magnetization transfer technique including magnetic susceptibility weighted imaging (SWI) and T2-weighted magnitude imaging (T2 * WI);image reconstruction technique such as quantitative susceptibility mapping (QSM).It is found that QSM can provide optimal signal-noise ratio to identify the boundary of STN,T2 * technique comes second.T2WI has high geometric accuracy when the patients wear frame,which is appropriate for direct DBS implantation on STN with frame. |
| Author | 孔维诗 路明宽 阳青松 陈智昌 仇一青 吴曦 |
| AuthorAffiliation | 海军军医大学学员旅;海军军医大学附属长海医院影像科;海军军医大学海医系;海军军医大学附属长海医院神经外科 |
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| Author_FL | LU Ming-kuan CHEN Zhi-chang QIU Yi-qing WU Xi KONG Wei-shi YANG Qing-song |
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| Keywords | 脑深部电刺激 magnetic resonance imaging 磁共振成像 subthalamic nucleus 帕金森病 Parkinson disease 丘脑底核 deep brain stimulation |
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| Notes | 31-1794/R KONG Wei-shi;LU Ming-kuan;YANG Qing-song;CHEN Zhi-chang;QIU Yi-qing;WU Xi;Cadet Brigade,Navy Military Medical University;Department of Medical Imaging,Changhai Hospital,Navy Military Medical University;Department of Navy Medicine,Navy Military Medical University;Department of Neurosurgery,Changhai Hospital,Navy Military Medical University |
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| PublicationTitle | 中国临床医学 |
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| Publisher | 海军军医大学学员旅,上海,200433%海军军医大学附属长海医院影像科,上海,200433%海军军医大学海医系,上海,200433%海军军医大学附属长海医院神经外科,上海,200433 |
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| Snippet | 丘脑底核（subthalamic nucleus,STN）是我国帕金森病患者接受脑深部电刺激（deep brain stimulation,DBS）治疗的主要核团。磁共振（MRI）影像个体化、精确植入电极至STN的感... R742; 丘脑底核(subthalamic nucleus,STN)是我国帕金森病患者接受脑深部电刺激(deep brain stimulation,DBS)治疗的主要核团.磁共振(MRI)影像个体化、精确植入电极至STN的感... |
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| SubjectTerms | 丘脑底核;磁共振成像;脑深部电刺激;帕金森病 |
| Title | 丘脑底核磁共振成像技术研究进展 |
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