Association between genetically proxied PCSK9 inhibition and prostate cancer risk: A Mendelian randomisation study - Fang, Si; Yarmolinsky, James; Gill, Dipender; Bull, Caroline J.; Perks, Claire M.; Davey Smith, George; Gaunt, Tom R.; Richardson, Tom G. (PLoS medicine, 2023)
Keywords: Age; Analysis; Biobanks; Biology and Life Sciences; Body mass index; Cancer; Cardiovascular disease; Care and treatment; Cholesterol; Cholesterol, LDL; Consortia; Drug targeting; Gene expression; Genes; Genetic analysis; Genetic aspects; Genetic diversity; Genetics; Genome-wide association studies; Genome-Wide Association Study; Genomes; Genomics; Health aspects; Humans; Lipids; Lipoprotein A; Liver; Low density lipoprotein; Low density lipoproteins; Male; Malignancy; Medicine and Health Sciences; Mendelian Randomization Analysis; Observational studies; Oncology, Experimental; Plasma levels; Polymorphism, Single Nucleotide; Prevention; Proprotein Convertase 9 - genetics; Prostate cancer; Prostatic Neoplasms - genetics; Risk factors; Single nucleotide polymorphisms; Single-nucleotide polymorphism; Statins; Testosterone; Therapeutic targets; Variables; United Kingdom; United Kingdom--UK