Genomic profiling of human vascular cells identifies TWIST1 as a causal gene for common vascular diseases - Nurnberg, Sylvia T.; Guerraty, Marie A.; Wirka, Robert C.; Rao, H. Shanker; Pjanic, Milos; Norton, Scott; Serrano, Felipe; Perisic, Ljubica; Elwyn, Susannah; Pluta, John; Zhao, Wei; Testa, Stephanie; et al. (PLoS genetics, 2020)
Keywords: Abdominal aortic aneurysm; Alleles; Aneurysm; Aorta; Aortic aneurysm; Biology and Life Sciences; Calcification; Calcification (Physiology); Cardiovascular disease; Cardiovascular diseases; Cells, Cultured; Coronary artery; Coronary heart disease; Coronary vessels; Coronary Vessels - cytology; Coronary Vessels - metabolism; Diseases; Endothelial cells; Endothelial Cells - metabolism; Endothelium; Endothelium, Vascular - cytology; Endothelium, Vascular - metabolism; Gene expression; Gene loci; Genes; Genetic research; Genome-wide association studies; Genomes; Genomics; Headache; Heart diseases; Humans; Immunoglobulin J Recombination Signal Sequence-Binding Protein - metabolism; Medicine; Medicine and Health Sciences; Migraine; Myocytes, Smooth Muscle - metabolism; Novels; Nuclear Proteins - genetics; Nuclear Proteins - metabolism; Phenotypes; Polymorphism, Single Nucleotide; Principal components analysis; Protein Binding; Quantitative genetics; Quantitative trait loci; Smooth muscle; Software; Splicing; Stat6 protein; Supervision; Transcriptome; Twist-Related Protein 1 - genetics; Twist-Related Protein 1 - metabolism; Vascular diseases; Vascular Diseases - genetics; Yes-associated protein; Sweden; California; United Kingdom--UK; United States--US; Pennsylvania