Mitochondrial DNA Released by Trauma Induces Neutrophil Extracellular Traps - Itagaki, Kiyoshi; Kaczmarek, Elzbieta; Lee, Yen Ting; Tang, I. Tien; Isal, Burak; Adibnia, Yashar; Sandler, Nicola; Grimm, Melissa J.; Segal, Brahm H.; Otterbein, Leo E.; Hauser, Carl J. (PloS one, 2015)
Keywords: 12-O-Tetradecanoylphorbol-13-acetate; Acetic acid; Age Factors; Aged; Antibacterial agents; Case-Control Studies; Cells, Cultured; Damage patterns; Deoxyribonucleic acid; DNA; DNA, Mitochondrial - metabolism; DNA, Mitochondrial - pharmacology; Elastase; Extracellular Traps - drug effects; Extracellular Traps - metabolism; Geriatrics; Hostages; Humans; Immune system; Immunology; Infections; Inflammation; Innate immunity; Medical schools; Medicine; Middle Aged; Mitochondria - metabolism; Mitochondrial DNA; NAD(P)H oxidase; Neutrophils; Neutrophils - drug effects; Neutrophils - metabolism; Older people; Oxidase; Oxidases; Patients; Peroxidase; Secondary infection; Stimulation; Surgery; Thrombosis; TLR9 protein; Toll-Like Receptor 9 - genetics; Toll-Like Receptor 9 - metabolism; Toll-like receptors; Trauma; Wounds and Injuries - metabolism; Young adults; Istanbul Turkey; Turkey; United States--US; Taiwan