Properties of Neurons Derived from Induced Pluripotent Stem Cells of Gaucher Disease Type 2 Patient Fibroblasts: Potential Role in Neuropathology - Sun, Ying; Florer, Jane; Mayhew, Christopher N.; Jia, Zhanfeng; Zhao, Zhiying; Xu, Kui; Ran, Huimin; Liou, Benjamin; Zhang, Wujuan; Setchell, Kenneth D. R.; Gu, Jianguo; Grabowski, Gregory A. (PloS one, 2015)
Keywords: Action potential; alpha-Synuclein - genetics; alpha-Synuclein - metabolism; Analysis; Anesthesiology; Brain research; Cell culture; Cells, Cultured; Disease; Drosophila; Enzymes; Fibroblasts; Fibroblasts - cytology; Fibroblasts - metabolism; Gangliosides; Gaucher Disease - pathology; Gaucher's disease; Genetics; Glucosidase; Glucosylceramidase - genetics; Glucosylceramidase - metabolism; Glucosylceramides - metabolism; Hospitals; Humans; Induced Pluripotent Stem Cells - cytology; Inhibitory postsynaptic potentials; Insects; Laboratories; Medicine; Membrane Potentials; Mutation; Neural Stem Cells - cytology; Neural Stem Cells - metabolism; Neurogenesis; Neurons; Neurons - cytology; Neurons - metabolism; Neurons - physiology; Pathogenesis; Patients; Pediatrics; Phenotypes; Pluripotency; Potassium; Potassium currents; Properties (attributes); Proteins; Psychosine - analogs & derivatives; Psychosine - metabolism; Sodium; Stem cells; Synuclein; United States--US; China; Ohio