Semi-Supervised Prediction of SH2-Peptide Interactions from Imbalanced High-Throughput Data - Kundu, Kousik; Costa, Fabrizio; Huber, Michael; Reth, Michael; Backofen, Rolf (PloS one, 2013)
Keywords: Amino acids; Analysis; Area Under Curve; Artificial Intelligence; Binding; Bioinformatics; Biology; Complexity; Computer applications; Computer programs; Computer Science; Genomes; Genomics; Homology; Humans; Immunology; Kinases; Learning algorithms; Leukemia; Ligands; Machine learning; Mathematical models; Models, Biological; Peptides; Performance prediction; Phosphorylation; Phosphotyrosine; Predictive Value of Tests; Protein Array Analysis - methods; Protein Binding; Protein Interaction Domains and Motifs - genetics; Protein Interaction Mapping - methods; Proteins; Regularization; ROC Curve; Signal transduction; src Homology Domains - genetics; src Homology Domains - physiology; Studies; Tar; Germany