Rapid antigen tests for SARS-CoV-2

Information on rapid antigen tests (RATs) for SARS-CoV-2 is presented. RATs detect SARS-CoV-2 antigens in samples from the upper respiratory tract and provide results in 15-30 minutes. Test sensitivities range from 30% to 80%, and specificities range from 98% to 100%, relative to reverse transcripti...

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Published inCanadian Medical Association journal (CMAJ) Vol. 193; no. 13; p. E447
Main Authors Liu, Michael, Arora, Rahul K., Krajden, Mel
Format Journal Article
LanguageEnglish
Published Canada Elsevier Inc 29.03.2021
Joule Inc
CMA Impact, Inc
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ISSN0820-3946
1488-2329
1488-2329
DOI10.1503/cmaj.202827

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Abstract Information on rapid antigen tests (RATs) for SARS-CoV-2 is presented. RATs detect SARS-CoV-2 antigens in samples from the upper respiratory tract and provide results in 15-30 minutes. Test sensitivities range from 30% to 80%, and specificities range from 98% to 100%, relative to reverse transcription polymerase chain reaction (RT-PCR). RATs can detect infection in people with viral loads that are associated with SARS-CoV-2 transmission, regardless of whether they are symptomatic or not.
AbstractList Information on rapid antigen tests (RATs) for SARS-CoV-2 is presented. RATs detect SARS-CoV-2 antigens in samples from the upper respiratory tract and provide results in 15-30 minutes. Test sensitivities range from 30% to 80%, and specificities range from 98% to 100%, relative to reverse transcription polymerase chain reaction (RT-PCR). RATs can detect infection in people with viral loads that are associated with SARS-CoV-2 transmission, regardless of whether they are symptomatic or not.
Audience Professional
Author Arora, Rahul K.
Krajden, Mel
Liu, Michael
Author_xml – sequence: 1
  givenname: Michael
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  organization: Harvard Medical School, Boston, Mass
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  givenname: Rahul K.
  surname: Arora
  fullname: Arora, Rahul K.
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  givenname: Mel
  surname: Krajden
  fullname: Krajden, Mel
  email: Mel.Krajden@bccdc.ca
  organization: Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC
BackLink https://www.ncbi.nlm.nih.gov/pubmed/33658245$$D View this record in MEDLINE/PubMed
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CitedBy_id crossref_primary_10_1016_j_idm_2021_06_008
crossref_primary_10_3923_ijv_2023_6_12
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COPYRIGHT 2021 Joule Inc.
Copyright Joule Inc Mar 29, 2021
2021 Joule Inc. or its licensors 2021
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SubjectTerms Antigens
Asymptomatic
Coronaviruses
COVID-19
COVID-19 diagnostic tests
Disease transmission
Humans
Immune system
Infections
Internal Medicine
Mass Screening
Practice
Public Health
SARS-CoV-2
Sensitivity and Specificity
Severe acute respiratory syndrome coronavirus 2
Testing
Title Rapid antigen tests for SARS-CoV-2
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