Sour Ageusia in Two Individuals Implicates Ion Channels of the ASIC and PKD Families in Human Sour Taste Perception at the Anterior Tongue - Huque, Taufiqul; Cowart, Beverly J.; Dankulich-Nagrudny, Luba; Pribitkin, Edmund A.; Bayley, Douglas L.; Spielman, Andrew I.; Feldman, Roy S.; Mackler, Scott A.; Brand, Joseph G. (PloS one, 2009)
Keywords: Acid Sensing Ion Channels; Acidity; Acids; Actin; Aged, 80 and over; Alcohol; Antibodies; Biopsy; Bitter taste; Calcium Channels - biosynthesis; Cell Biology/Cell Signaling; Cell Biology/Gene Expression; Cell Biology/Neuronal Signaling Mechanisms; Cell lineage; Dentistry; Epithelial Sodium Channels - biosynthesis; Family; Female; Gene Expression Regulation; Genetics and Genomics/Gene Expression; Genomic analysis; Humans; Immunohistochemistry; Ion channels; Kidney diseases; Kidney transplantation; Male; Mammals; Middle Aged; Nerve Tissue Proteins - biosynthesis; Neuroscience/Behavioral Neuroscience; Neuroscience/Neuronal Signaling Mechanisms; Neuroscience/Sensory Systems; Otolaryngology; Papillae; Patients; Perception; Phospholipase; Phospholipase C; Phospholipase C beta - biosynthesis; Polycystic kidney; Polymerase chain reaction; Potassium; Receptors, Cell Surface - biosynthesis; Receptors, G-Protein-Coupled - biosynthesis; Salty taste; Sodium; Sodium channels; Sodium Channels - biosynthesis; Sour taste; Stimuli; Sweet taste; Taste; Taste (Sense); Taste - genetics; Taste - physiology; Taste Buds - metabolism; Taste disorders; Taste perception; Taste receptors; Tongue; Tongue - metabolism; New York; United States--US; Pennsylvania