GRAM: A GeneRAlized Model to predict the molecular effect of a non-coding variant in a cell-type specific manner - Lou, Shaoke; Cotter, Kellie A.; Li, Tianxiao; Liang, Jin; Mohsen, Hussein; Liu, Jason; Zhang, Jing; Cohen, Sandra; Xu, Jinrui; Yu, Haiyuan; Rubin, Mark A.; Gerstein, Mark (PLoS genetics, 2019)
Keywords: Algorithms; Analysis; Binding Sites; Biochemistry; Bioinformatics; Biology and Life Sciences; Biomedical research; Biophysics; Cell lines; Cells (Biology); Computer Simulation; Epigenetic inheritance; Epigenetics; Evolutionary conservation; Forecasting - methods; Funding; Gene expression; Gene Expression Regulation - genetics; Gene mapping; Genetic aspects; Genetic Variation - genetics; Genomes; Genomic structural variations; Genomics - methods; Humans; Linkage Disequilibrium - genetics; Luciferase; Medicine; Models, Genetic; Molecular biology; Mutation; Observations; Phenotypes; Physical Sciences; Protein Binding - genetics; Proteins; Quantitative Trait Loci - genetics; Reporter gene; Research and Analysis Methods; Sequence Analysis, DNA - methods; Software; Transcription (Genetics); Transcription Factors - genetics; United States; New York; United States--US; Switzerland; Connecticut