Analysis of Genetic Variation in CYP450 Genes for Clinical Implementation - Goh, Liuh Ling; Lim, Chia Wei; Sim, Wey Cheng; Toh, Li Xian; Leong, Khai Pang (PloS one, 2017)
Keywords: Alleles; Annotations; Asian Continental Ancestry Group - genetics; Automation; Biology and Life Sciences; China; Clinical medicine; Consortia; Copy number; CYP2D6 protein; Cytochrome; Cytochrome P-450; Cytochrome P-450 Enzyme System - genetics; Cytochrome P450; Deoxyribonucleic acid; DNA; Drug metabolism; Drug therapy; Enzyme Assays; Enzymes; Ethnic Groups - genetics; Gene Frequency; Genes; Genetic aspects; Genetic diversity; Genetic Loci; Genetic Variation; Genomics; Genotype & phenotype; Genotypes; Genotyping; Haplotypes - genetics; Humans; Identification and classification; India; Knowledge bases (artificial intelligence); Laboratories; Malaysia; Medicine and Health Sciences; Metabolism; Minority & ethnic groups; People and places; Pharmacogenomics; Pharmacological research; Pharmacology; Phenotype; Precision medicine; Properties; Reproducibility of Results; Research and Analysis Methods; Singapore; Single nucleotide polymorphisms; Single-nucleotide polymorphism; Test procedures; Therapy; Toxicity; Workflow