Systemic Immune Activation in HIV Infection Is Associated with Decreased MDC Responsiveness to TLR Ligand and Inability to Activate Naive CD4 T-Cells - Yonkers, Nicole L.; Rodriguez, Benigno; Asaad, Robert; Lederman, Michael M.; Anthony, Donald D. (PloS one, 2011)
Keywords: Acquired immune deficiency syndrome; Adult; AIDS; Antiviral agents; B7-2 Antigen - metabolism; Cardiovascular disease; CD4 antigen; CD4-Positive T-Lymphocytes - immunology; CD4-Positive T-Lymphocytes - metabolism; CD83 antigen; CD86 antigen; Cell activation; Cytokines; Dendritic cells; Dendritic Cells - immunology; Dendritic Cells - secretion; gamma -Interferon; Health aspects; Histocompatibility antigen HLA; HIV; HIV infections; HIV Infections - immunology; HIV Seropositivity - immunology; HLA-DR Antigens - metabolism; Human immunodeficiency virus; Humans; Immune response; Immune system; Infection; Infections; Interferon; Interleukin 2; Interleukin 6; Interleukin-6 - secretion; Ligands; Lymphocytes T; Male; Medicine; Middle Aged; Myeloid Cells - immunology; Pathogens; Phenotype; Poly I-C - immunology; Proteins; T cell receptors; T cells; Toll-like receptors; Toll-Like Receptors - metabolism; Up-Regulation - immunology; Viruses; Young Adult; Cleveland Ohio; United States--US