Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus - Bell, Christopher G.; Finer, Sarah; Lindgren, Cecilia M.; Wilson, Gareth A.; Rakyan, Vardhman K.; Teschendorff, Andrew E.; Akan, Pelin; Stupka, Elia; Down, Thomas A.; Prokopenko, Inga; Morison, Ian M.; Mill, Jonathan; et al. (PloS one, 2010)
Keywords: Adult; Algorithms; Analysis; Animals; Base Sequence; Bayes Theorem; Bayesian analysis; Bioinformatics; Cancer; CpG islands; CpG Islands - genetics; Data analysis; Dentistry; Deoxyribonucleic acid; Diabetes; Diabetes and Endocrinology/Obesity; Diabetes and Endocrinology/Type 2 Diabetes; Diabetes mellitus; Diabetes Mellitus, Type 2 - genetics; Diabetes Mellitus, Type 2 - metabolism; Disease; Disease susceptibility; DNA; DNA Methylation; Epigenetic inheritance; Epigenetics; Epigenomics; Evolution, Molecular; Female; Females; Gene expression; Gene Expression Profiling; Gene Frequency; Genetic aspects; Genetic Predisposition to Disease - genetics; Genetics; Genetics and Genomics/Comparative Genomics; Genetics and Genomics/Complex Traits; Genetics and Genomics/Epigenetics; Genetics and Genomics/Population Genetics; Genomes; Genomics; Genotype; Haplotypes; Haplotypes - genetics; Histones - metabolism; Humans; Immunoprecipitation; Loci; Medical research; Medicine; Methylation; Mutation; Obesity; Obesity - genetics; Oligonucleotide Array Sequence Analysis; Polymorphism, Single Nucleotide; Science; Sequence Analysis, DNA; Single nucleotide polymorphisms; Single-nucleotide polymorphism; Susceptibility; Type 2 diabetes