Pharmacogenetics: Implications of race and ethnicity on defining genetic profiles for personalized medicine - Ortega, Victor E.; Meyers, Deborah A. (Journal of allergy and clinical immunology, 2014)
Keywords: admixture mapping; Adrenergic beta-Agonists - therapeutic use; Adult; African Americans; Allergy and Immunology; Asthma; Asthma - drug therapy; Asthma - ethnology; Asthma - genetics; Binding sites; Biological and medical sciences; Chronic obstructive pulmonary disease, asthma; Clinical trials; ethnic group; European Continental Ancestry Group; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Genealogy; genes; Genetic diversity; Genome-Wide Association Study; Genotype; Heart failure; Hispanic Americans; Humans; Immunopathology; Medical sciences; Mortality; Mutation; pharmacogenetics; Pharmacogenetics - trends; Pneumology; Polymorphism, Single Nucleotide; Population; Precision medicine; Precision Medicine - methods; Race; Receptors, Adrenergic, beta-2 - genetics; response heterogeneity; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; single nucleotide polymorphism; Studies; United States--US; GWAS; single nucleotide polymorphism; admixture mapping; ADRB1; ADRB2; BARGE; GRK5; SNP; LARGE; LABA; CAAPA; SMART; PEFR; genes; SABA; NIH; GALA; Asthma; NHLBI; ICS; SPATS2L; ethnic group; response heterogeneity; BADGER; GLCCl1; pharmacogenetics; β 1-Adrenergic receptor; National Heart, Lung, and Blood Institute; Long-acting β-agonist; National Institutes of Health; Genome-wide association study; Best Add-on Therapy Giving Effective Response Trial; Spermatogenesis-associated, serine-rich 2-like gene; Short-acting β-agonist; Salmeterol Multicenter Asthma Research Trial; Inhaled corticosteroid; Consortium on Asthma among African-ancestry Populations in the Americas; Long-acting Beta Agonist Response by Genotype; Genetics of Asthma in Latino Americans; G protein receptor kinase 5; Peak expiratory flow rate; Glucocorticoid-induced transcript 1 gene; β 2-Adrenergic receptor; Beta Agonist Response by Genotype Trial; Lung disease; Cartography; Immunopathology; Pharmacogenetics; Genetic variability; Respiratory disease; Genotype; Ethnic group; Heterogeneity; Immunology; Gene; Race; Bronchus disease