Mitophagy promotes sorafenib resistance through hypoxia-inducible ATAD3A dependent Axis - Wu, Hong; Wang, Tao; Liu, Yiqiang; Li, Xin; Xu, Senlin; Wu, Changtao; Zou, Hongbo; Cao, Mianfu; Jin, Guoxiang; Lang, Jinyi; Wang, Bin; Liu, Baohua; et al. (Journal of experimental & clinical cancer research, 2020)
Keywords: Adenosine triphosphatase; Angiogenesis; Animals; Antibodies; Antineoplastic Agents - pharmacology; Apoptosis; ATAD3A; ATPases Associated with Diverse Cellular Activities - metabolism; Autophagy; Biomedical and Life Sciences; Biomedicine; Cancer Research; Cancer therapies; Cell Line, Tumor; Drug resistance; Drug Resistance, Neoplasm; Female; Gene expression; Genes; Growth factors; Humans; Hypoxia; Hypoxia and Tumors; Immunology; Inhibitor drugs; Kinases; Liver cancer; Liver Neoplasms - drug therapy; Liver Neoplasms - metabolism; Liver Neoplasms - pathology; Membrane Proteins - metabolism; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondrial Proteins - metabolism; Mitophagy; Mitophagy - drug effects; Oncology; Proteins; RNA; RNA sequencing; Sorafenib - pharmacology; Sorafenib resistance; Targeted cancer therapy; Tumor Hypoxia - physiology; Tumors; Beijing China; United States--US; China; Hypoxia; Sorafenib resistance; Mitophagy; ATAD3A