Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations - Ge, Tian; Irvin, Marguerite R.; Patki, Amit; Srinivasasainagendra, Vinodh; Lin, Yen-Feng; Tiwari, Hemant K.; Armstrong, Nicole D.; Benoit, Barbara; Chen, Chia-Yen; Choi, Karmel W.; Cimino, James J.; Davis, Brittney H.; et al. (Genome medicine, 2022)
Keywords: African Americans; Algorithms; Bayes Theorem; Bayesian analysis; Biobanks; Bioinformatics; Biomedical and Life Sciences; Biomedicine; Cancer Research; Clinical implementation; Codes; Consortia; Diabetes; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - genetics; Disease; Diverse populations; Electronic health records; Electronic medical records; Family medical history; Genealogy; Genetic aspects; Genetic Predisposition to Disease; Genome-wide association studies; Genome-Wide Association Study; Genomes; Genomics; Glucose; Health risk assessment; Human Genetics; Humans; Intervention; Medical records; Medical research; Medicine, Experimental; Medicine/Public Health; Meta-analysis; Metabolomics; Polygenic risk score; Population; Prospective Studies; Risk Factors; Systems Biology; Type 2 diabetes; Taiwan; Polygenic risk score; Type 2 diabetes; Clinical implementation; Diverse populations