European cardiovascular magnetic resonance (EuroCMR) registry – multi national results from 57 centers in 15 countries

• Published in: Journal of cardiovascular magnetic resonance Vol. 15; no. 1; p. 9
• Main Authors: Bruder, Oliver, Wagner, Anja, Lombardi, Massimo, Schwitter, Jürg, van Rossum, Albert, Pilz, Günter, Nothnagel, Detlev, Steen, Henning, Petersen, Steffen, Nagel, Eike, Prasad, Sanjay, Schumm, Julia, Greulich, Simon, Cagnolo, Alessandro, Monney, Pierre, Deluigi, Christina C, Dill, Thorsten, Frank, Herbert, Sabin, Georg, Schneider, Steffen, Mahrholdt, Heiko
• Format: Journal Article
• Language: English
• Published: London Elsevier Inc 18.01.2013; BioMed Central; BioMed Central Ltd; Elsevier
• Subjects: Aged; Angiology; Assessments; Biomedical research; Cardiology; Cardiovascular disease; Cardiovascular diseases; Cardiovascular magnetic resonance; Chi-Square Distribution; Clinical medicine; Computer aided design; Diagnosis; Europe; Female; Heart attacks; Heart Diseases - diagnosis; Heart Diseases - mortality; Heart Diseases - pathology; Heart Diseases - physiopathology; Heart Diseases - therapy; Heart muscle; Humans; Hypothesis testing; Image quality; Imaging; Impact; Indication; Internal medicine; Ischemia; Kaplan-Meier Estimate; Magnetic resonance imaging; Magnetic Resonance Imaging - adverse effects; Male; Management; Management science; Medical imaging; Medicine; Medicine & Public Health; Middle Aged; Myocardium - pathology; Patient management; Patients; Physiological aspects; Predictive Value of Tests; Prognosis; Quality; Radiology; Registries; Registry; Risk Assessment; Risk Factors; Routines; Safety; Severity of Illness Index; Stratification; Studies; Therapeutic implications; Tissue Survival; Trends; Europe; Germany; Impact; Cardiovascular magnetic resonance; Therapeutic implications; Quality; Registry; Safety; Patient management
• ISSN: 1097-6647; 1532-429X; 1532-429X
• DOI: 10.1186/1532-429X-15-9

The EuroCMR registry sought to evaluate indications, image quality, safety and impact on patient management of clinical routine CMR in a multi-national European setting. Furthermore, interim analysis of the specific protocols should underscore the prognostic potential of CMR. Multi-center registry with consecutive enrolment of patients in 57 centers in 15 countries. More than 27000 consecutive patients were enrolled. The most important indications were risk stratification in suspected CAD/Ischemia (34.2%), workup of myocarditis/cardiomyopathies (32.2%), as well as assessment of viability (14.6%). Image quality was diagnostic in more than 98% of cases. Severe complications occurred in 0.026%, always associated with stress testing. No patient died during or due to CMR. In 61.8% CMR findings impacted on patient management. Importantly, in nearly 8.7% the final diagnosis based on CMR was different to the diagnosis before CMR, leading to a complete change in management. Interim analysis of suspected CAD and risk stratification in HCM specific protocols revealed a low rate of adverse events for suspected CAD patients with normal stress CMR (1.0% per year), and for HCM patients without LGE (2.7% per year). The most important indications in Europe are risk stratification in suspected CAD/Ischemia, work-up of myocarditis and cardiomyopathies, as well as assessment of viability. CMR imaging is a safe procedure, has diagnostic image quality in more than 98% of cases, and its results have strong impact on patient management. Interim analyses of the specific protocols underscore the prognostic value of clinical routine CMR in CAD and HCM. The EuroCMR registry sought to evaluate indications, image quality, safety and impact on patient management of clinical routine CMR in a multi-national European setting in a large number of cases (n > 27000). Based on our data CMR is frequently performed in European daily clinical routine. The most important indications in Europe are risk stratification in suspected CAD/Ischemia, work-up of myocarditis and cardiomyopathies, as well as assessment of viability. CMR imaging is a safe procedure, has diagnostic image quality in more than 98% of cases, and its results have strong impact on patient management. Interim analyses of the specific protocols underscore the prognostic value of clinical routine CMR in CAD and HCM.