Long-term effectiveness of local BM-MSCs for skeletal muscle regeneration: a proof of concept obtained on a pig model of severe radiation burn - Linard, Christine; Brachet, Michel; L’homme, Bruno; Strup-Perrot, Carine; Busson, Elodie; Bonneau, Michel; Lataillade, Jean-Jacques; Bey, Eric; Benderitter, Marc (Stem cell research & therapy, 2018)
Keywords: Angiogenesis; Animals; Antigens, CD34 - metabolism; Autografts; Biomedical and Life Sciences; Biomedical Engineering and Bioengineering; BM-MSC; Bone marrow; Bone Marrow Cells - cytology; Bone surgery; Burns - pathology; Burns - physiopathology; Burns - therapy; Calcium signalling; Capillaries; Care and treatment; Cell Biology; Cell cycle; Cell Differentiation - genetics; Collagen; Degeneration; Disease Models, Animal; Excision (Surgery); Extracellular Matrix - metabolism; Fibroblasts; Gangrene; Gene expression; Gene Expression Regulation; Growth factors; Health aspects; Inflammation; Injections; Irradiation; Life Sciences; Macrophages; Macrophages - metabolism; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells - cytology; Mesenchyme; Muscle; Muscle Fibers, Skeletal - pathology; Muscle regeneration; Muscle, Skeletal - blood supply; Muscle, Skeletal - physiopathology; Muscular dystrophy; Musculoskeletal system; Oxidative stress; Phenotype; Pig; Plastic surgery; Radiation; Radiation Injuries - pathology; Radiation Injuries - physiopathology; Radiation Injuries - therapy; Regeneration; Regenerative Medicine/Tissue Engineering; Skeletal muscle; Skin; Stem Cells; Stromal cells; Swine; Time Factors; Trauma; Treatment Outcome; Vascular endothelial growth factor; Wound healing; Irradiation; Regeneration; BM-MSC; Muscle; Pig