Identification of Key Processes that Control Tumor Necrosis Factor Availability in a Tuberculosis Granuloma - Fallahi-Sichani, Mohammad; Schaller, Matthew A.; Kirschner, Denise E.; Kunkel, Steven L.; Linderman, Jennifer J. (PLoS computational biology, 2010)
Keywords: Algorithms; Animals; Apoptosis - physiology; Bacteria; Biophysics; Care and treatment; Computational Biology/Systems Biology; Computer Simulation; Cytokines; Dendritic Cells - immunology; Experiments; Granuloma; Granuloma - immunology; Granuloma - metabolism; Granuloma - microbiology; Granuloma - pathology; Immune system; Immunology; Infectious Diseases; Lungs; Lymphatic system; Lymphocytes; Lymphocytes - immunology; Macrophages - immunology; Mathematical models; Mice; Mice, Inbred CBA; Models, Biological; Mycobacterium tuberculosis; Partial differential equations; Physiological aspects; Protein Binding; Proteins; Receptors, Tumor Necrosis Factor - metabolism; Risk factors; Sensitivity analysis; Studies; Tuberculin - metabolism; Tuberculosis; Tuberculosis - immunology; Tuberculosis - metabolism; Tuberculosis - pathology; Tumor necrosis factor; Tumor Necrosis Factor-alpha - antagonists & inhibitors; Tumor Necrosis Factor-alpha - metabolism; United States; Granuloma; Dendritic Cells; Tuberculin; Macrophages; Tumor Necrosis Factor-alpha; Algorithms; Animals; Tuberculosis; Mycobacterium tuberculosis; Receptors, Tumor Necrosis Factor; Lymphocytes; Models, Biological; Computer Simulation; Mice, Inbred CBA; Protein Binding; Mice; Apoptosis