DNA methylation-based classification of central nervous system tumours - Capper, David; Jones, David T. W.; Hovestadt, Volker; Schrimpf, Daniel; Sturm, Dominik; Kratz, Annekathrin; Huang, Kristin; Pajtler, Kristian W.; Lindenberg, Kerstin; Harter, Patrick N.; Braczynski, Anne K.; Plate, Karl H.; et al. (Nature (London), 2018)
Keywords: 13/56; 45/61; 631/114/1386; 631/114/2407; 631/67/1922; 631/67/69; Adolescent; Adult; Aged; Aged, 80 and over; Bioinformatics; Brain cancer; Cancer; Cancer diagnosis; Central nervous system; Central Nervous System Neoplasms - classification; Central Nervous System Neoplasms - diagnosis; Central Nervous System Neoplasms - genetics; Central Nervous System Neoplasms - pathology; Child; Child, Preschool; Classification; Classifiers; Clinical trials; Cohort Studies; Data processing; Deoxyribonucleic acid; Diagnosis; Diagnostic software; Diagnostic systems; DNA; DNA Methylation; DNA sequencing; Female; Gene expression; Generalized linear models; Genetic aspects; Genomes; Humanities and Social Sciences; Humans; Identification and classification; Infant; Learning algorithms; Machine learning; Male; Medical examination; Methods; Methylation; Middle Aged; multidisciplinary; Nervous system; Observations; Probability; Reproducibility of Results; Science; Standardization; Tumors; Unsupervised Machine Learning; Young Adult; Germany