Leveraging type 1 diabetes human genetic and genomic data in the T1D knowledge portal

To address the challenge of translating genetic discoveries for type 1 diabetes (T1D) into mechanistic insight, we have developed the T1D Knowledge Portal (T1DKP), an open-access resource for hypothesis development and target discovery in T1D.

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Bibliographic Details
Published inPLoS biology Vol. 21; no. 8; p. e3002233
Main Authors Kudtarkar, Parul, Costanzo, Maria C., Sun, Ying, Jang, Dongkeun, Koesterer, Ryan, Mychaleckyj, Josyf C., Nayak, Uma, Onengut-Gumuscu, Suna, Rich, Stephen S., Flannick, Jason A., Gaulton, Kyle J., Burtt, Noël P.
Format Journal Article
LanguageEnglish
Published United States Public Library of Science 10.08.2023
Public Library of Science (PLoS)
Subjects
Annotations
Biobanks
Bioinformatics
Biology and Life Sciences
Datasets
Diabetes
Diabetes mellitus
Diabetes mellitus (insulin dependent)
Disease prevention
Genes
Genetic aspects
Genetic engineering
Genomes
Hypotheses
Information services
Knowledge
Medicine and Health Sciences
Online information services
Online services
Online tutorials
Pathogenesis
Service development
Subject specialists
Type 1 diabetes
United States
Online AccessGet full text
ISSN1545-7885
1544-9173
1545-7885
DOI10.1371/journal.pbio.3002233

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Summary:To address the challenge of translating genetic discoveries for type 1 diabetes (T1D) into mechanistic insight, we have developed the T1D Knowledge Portal (T1DKP), an open-access resource for hypothesis development and target discovery in T1D.
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I have read the journal’s policy and the authors of this manuscript have the following competing interests: KG holds stock in Neurocrine biosciences and has done consulting for Genentech.
SSR, JAF, KJG, and NPB also contributed equally to this work.
ISSN:1545-7885
1544-9173
1545-7885
DOI:10.1371/journal.pbio.3002233