Comprehensive Analysis of Disease-Related Genes in Chronic Lymphocytic Leukemia by Multiplex PCR-Based Next Generation Sequencing - Vollbrecht, Claudia; Mairinger, Fabian Dominik; Koitzsch, Ulrike; Peifer, Martin; Koenig, Katharina; Heukamp, Lukas Carl; Crispatzu, Giuliano; Wilden, Laura; Kreuzer, Karl-Anton; Hallek, Michael; Odenthal, Margarete; Herling, Carmen Diana; et al. (PloS one, 2015)
Keywords: Adult; Aged; Aged, 80 and over; Algorithms; Analysis; B-cell receptor; Bioinformatics; Cancer; Cancer genetics; Chronic lymphatic leukemia; Chronic lymphocytic leukemia; Clinical medicine; Cytometry; Deoxyribonucleic acid; Development and progression; Diagnostic systems; Dilution; Disease; Disease resistance; DNA; Drug resistance; Female; Flow cytometry; Gene Library; Gene mutation; Gene sequencing; Genes; Genetic aspects; Genetic Association Studies; Genetic Variation; Genomes; Genomics; High-Throughput Nucleotide Sequencing; Hospitals; Hot spots; Humans; Internal medicine; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis; Leukemia, Lymphocytic, Chronic, B-Cell - genetics; Lymphatic leukemia; Lymphocytes B; Lymphoma; Lymphomas; Male; Medicine; Middle Aged; Molecular chains; Multiplex Polymerase Chain Reaction - methods; Multiplex Polymerase Chain Reaction - standards; Multiplexing; Mutation; MyD88 protein; Next-generation sequencing; Notch1 protein; Oncology; p53 Protein; Pathology; Patients; Peripheral blood; Polymerase chain reaction; Prognosis; Proteins; Sensitivity and Specificity; Signaling; Tumor proteins; ZAP-70 protein; Germany