Activation of HIV Transcription by the Viral Tat Protein Requires a Demethylation Step Mediated by Lysine-specific Demethylase 1 (LSD1/KDM1) - Sakane, Naoki; Kwon, Hye-Sook; Pagans, Sara; Kaehlcke, Katrin; Mizusawa, Yasuhiro; Kamada, Masafumi; Lassen, Kara G.; Chan, Jonathan; Greene, Warner C.; Schnoelzer, Martina; Ott, Melanie (PLoS pathogens, 2011)
Keywords: Acetylation; Animals; DNA methylation; Epigenesis, Genetic - physiology; Epigenetics; Experiments; Flow cytometry; Genes, Viral - drug effects; Genetic aspects; Genetic transcription; Histone Demethylases - antagonists & inhibitors; Histone Demethylases - metabolism; HIV; HIV (Viruses); Human immunodeficiency virus; Infections; Kinases; Lymphocytes; Mass spectrometry; Medical research; Medicine; Methylation; Methyltransferases; Peptides; Phenelzine - pharmacology; Physiological aspects; Positive Transcriptional Elongation Factor B - metabolism; Proteins; Rabbits; tat Gene Products, Human Immunodeficiency Virus - immunology; tat Gene Products, Human Immunodeficiency Virus - metabolism; Transcription, Genetic - drug effects; Viral proteins; United States; Germany