Blocking of PDL-1 Interaction Enhances Primary and Secondary CD8 T Cell Response to Herpes Simplex Virus-1 Infection - Channappanavar, Rudragouda; Twardy, Brandon S.; Suvas, Susmit (PloS one, 2012)
Keywords: Acute Disease; Animals; Antibodies, Monoclonal - pharmacology; Antigens; Apoptosis; Assaying; B7-H1 Antigen - antagonists & inhibitors; B7-H1 Antigen - genetics; B7-H1 Antigen - immunology; Bacterial infections; Biology; CD11c antigen; CD11c Antigen - genetics; CD11c Antigen - immunology; CD8 antigen; CD8-Positive T-Lymphocytes - drug effects; CD8-Positive T-Lymphocytes - immunology; CD8-Positive T-Lymphocytes - virology; Cytokines; Cytotoxicity; Degranulation; Dendritic cells; Dendritic Cells - drug effects; Dendritic Cells - immunology; Dendritic Cells - virology; Female; Gene Expression - immunology; Health aspects; Herpes simplex; Herpes Simplex - drug therapy; Herpes Simplex - immunology; Herpes Simplex - virology; Herpes simplex virus; Herpes viruses; Herpesvirus 1, Human - drug effects; Herpesvirus 1, Human - physiology; Humans; Immunization; Immunoassay; Immunodominant Epitopes - administration & dosage; Immunodominant Epitopes - genetics; Immunodominant Epitopes - immunology; Immunologic Memory - drug effects; Immunological memory; Infection; Infections; Injections, Intraperitoneal; Injections, Subcutaneous; Ligands; Lymphocytes; Lymphocytes T; Medicine; Mice; Mice, Inbred C57BL; Monoclonal antibodies; Oligopeptides - administration & dosage; Oligopeptides - genetics; Oligopeptides - immunology; PD-1 protein; Peptides; Priming; Spleen; T cell receptors; T cells; Toxicity; Vaccines; Viral infections; Virus diseases; Viruses; United States--US; Michigan