Structural and Logical Analysis of a Comprehensive Hedgehog Signaling Pathway to Identify Alternative Drug Targets for Glioma, Colon and Pancreatic Cancer - Chowdhury, Saikat; Pradhan, Rachana N.; Sarkar, Ram Rup (PloS one, 2013)
Keywords: Aberration; Analysis; Antineoplastic agents; Antineoplastic Agents - pharmacology; Antineoplastic Agents - therapeutic use; Biology; Boolean algebra; Brain tumors; Cancer; Cancer therapies; Cellular proteins; Chemical engineering; Colon; Colon cancer; Colonic Neoplasms - drug therapy; Colonic Neoplasms - metabolism; Computation; Computer applications; Computer Simulation; Drug therapy; External stimuli; Gene expression; Genomics; Glioma; Glioma - drug therapy; Glioma - metabolism; Gliomas; Health aspects; Hedgehog protein; Hedgehog Proteins - metabolism; Humans; Laboratories; Ligands; Medical research; Medicine; Molecular interactions; Molecular Targeted Therapy; Mutation; Pancreatic cancer; Pancreatic Neoplasms - drug therapy; Pancreatic Neoplasms - metabolism; Parameter identification; Perturbation methods; Proteins; Regulations; Signal transduction; Signal Transduction - drug effects; Signaling; Stem cells; Structural analysis; Studies; Target recognition; India