Analysis of SHIP1 expression and activity in Crohn’s disease patients - Somasundaram, Rajesh; Fernandes, Sandra; Deuring, Jasper J.; de Haar, Colin; Kuipers, Ernst J.; Vogelaar, Lauran; Middleton, Frank A.; van der Woude, C. Janneke; Peppelenbosch, Maikel P.; Kerr, William G.; Fuhler, Gwenny M. (PloS one, 2017)
Keywords: Aberration; Adaptive immunity; Adult; Authorship; Autophagy-Related Proteins - genetics; Biology and Life Sciences; Biopsy; Bone marrow; Cell Line; Cohort Studies; Correlation; Crohn Disease - genetics; Crohn Disease - metabolism; Crohn's disease; Deoxyribonucleic acid; Deregulation; DNA; Down-Regulation; Female; Fibrosis; Gastroenterology; Gene expression; Gene Expression Regulation; Genetic aspects; Genetic Association Studies; Genetic Predisposition to Disease; Hepatology; Humans; Ileitis; Immune response; Immunity; Immunology; Inflammatory bowel disease; Inositol; Inositol-1,4,5-trisphosphate 5-phosphatase; Intestine; Leukocytes (mononuclear); Malachite green; Male; Medicine and Health Sciences; Mice; Middle Aged; Patients; People and Places; Peripheral blood mononuclear cells; Phosphatase; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases - genetics; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases - metabolism; Polymerase chain reaction; Polymorphism; Polymorphism, Single Nucleotide; Proteins; Remission; Research and Analysis Methods; Single-nucleotide polymorphism; Small intestine; Western blotting; Young Adult