Transient receptor potential cation channel, subfamily V, member 4 and airway sensory afferent activation: Role of adenosine triphosphate - Bonvini, Sara J.; Birrell, Mark A.; Grace, Megan S.; Maher, Sarah A.; Adcock, John J.; Wortley, Michael A.; Dubuis, Eric; Ching, Yee-Man; Ford, Anthony P.; Shala, Fisnik; Miralpeix, Montserrat; Tarrason, Gema; et al. (Journal of allergy and clinical immunology, 2016)
Keywords: Adenosine Triphosphate - metabolism; Allergy and Immunology; Animals; Asthma; ATP; Calcium Signaling; Chronic obstructive pulmonary disease; Cough; Dose-Response Relationship, Drug; Experiments; Genetic engineering; Guinea Pigs; hypotonicity; ion channels; Male; Mechanisms of Allergy and Clinical Immunology; Mice; Mice, Knockout; Nerve Fibers, Myelinated - drug effects; Nerve Fibers, Myelinated - metabolism; Neurons; Neurons, Afferent - drug effects; Neurons, Afferent - metabolism; Neurosciences; Nodose Ganglion - cytology; Nodose Ganglion - drug effects; Nodose Ganglion - metabolism; Purinergic P2X Receptor Antagonists - pharmacology; Respiratory System - innervation; Respiratory System - metabolism; Rodents; sensory nerves; Transient receptor potential; TRPV Cation Channels - agonists; TRPV Cation Channels - metabolism; vagus; Vagus Nerve - drug effects; Vagus Nerve - physiology; RAR; [Ca2+]i; DiI; DMSO; K50; Px1; hypotonicity; αβ-MeATP; cough; Transient receptor potential; ion channels; sensory nerves; AUC; CV; TRP; ECS; vagus; 4α-PDD; TRPV4; NCBI; ATP; COPD; National Center for Biotechnology Information; 50 mmol/L Potassium chloride solution; Conduction velocity; 1,1′-Dioctacetyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate; Pannexin 1; Area under the curve; Chronic obstructive pulmonary disease; Rapidly adapting stretch receptor; [Ca 2+] i; Transient receptor potential cation channel, subfamily V, member 4; Intracellular free calcium; Dimethyl sulfoxide; 4α Phorbol 12,13-didecanoate; αβ-Methylene-ATP; Extracellular solution