Effects of Aerobic Exercise Alone on Lipids in Healthy East Asians: A Systematic Review and Meta-Analysis
Aim: The purpose of the current work was to review the effects of regular aerobic exercise on serum lipid and lipoprotein levels in East Asians using meta-analysis. Methods: The randomized controlled trials analyzed involved healthy adults who were East Asians with a mean age ≥40 years, an exercise...
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| Published in | Journal of Atherosclerosis and Thrombosis Vol. 26; no. 5; pp. 488 - 503 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Japan
Japan Atherosclerosis Society
01.05.2019
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1340-3478 1880-3873 1880-3873 |
| DOI | 10.5551/jat.45864 |
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| Abstract | Aim: The purpose of the current work was to review the effects of regular aerobic exercise on serum lipid and lipoprotein levels in East Asians using meta-analysis. Methods: The randomized controlled trials analyzed involved healthy adults who were East Asians with a mean age ≥40 years, an exercise group that only performed regular aerobic exercise, and a control group that did not carry out exercise-related intervention; the trials indicated mean high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), or triglyceride (TG). The mean difference (MD) was defined as the difference (mean value at post-intervention in the exercise group－mean value at baseline in the exercise group)－(mean value at post-intervention in the control group－mean value at baseline in the control group) in HDL-C, LDL-C, TC, and TG and was calculated for each trial. The weighted MD was calculated with a random-effects model. Results: The meta-analysis examined 994 subjects in 25 studies. The weighted MD in HDL-C, TC, and TG improved significantly (HDL-C, 2.2 mg/dL; TC, －5.8 mg/dL; TG, －13.7 mg/dL). The weighted MD in HDL-C and TC contained significant heterogeneity (HDL-C, I2＝45.1%; TC, I2＝56.2%). When trials were limited to those involving moderate-intensity exercise (55%–69% of the maximum heart rate) or an exercise volume ≥150 min/week, the weighted MD in HDL-C, LDL-C, TC, and TG improved significantly and did not contain significant heterogeneity.Conclusions: The findings suggest that the ideal form of exercise to improve lipid and lipoprotein levels in East Asians is exercise of moderate-intensity and in a volume ≥150 min/week. |
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| AbstractList | Aim: The purpose of the current work was to review the effects of regular aerobic exercise on serum lipid and lipoprotein levels in East Asians using meta-analysis. Methods: The randomized controlled trials analyzed involved healthy adults who were East Asians with a mean age ≥ 40 years, an exercise group that only performed regular aerobic exercise, and a control group that did not carry out exercise-related intervention; the trials indicated mean high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), or triglyceride (TG). The mean difference (MD) was defined as the difference (mean value at post-intervention in the exercise group − mean value at baseline in the exercise group) − (mean value at post-intervention in the control group − mean value at baseline in the control group) in HDL-C, LDL-C, TC, and TG and was calculated for each trial. The weighted MD was calculated with a random-effects model. Results: The meta-analysis examined 994 subjects in 25 studies. The weighted MD in HDL-C, TC, and TG improved significantly (HDL-C, 2.2 mg/dL; TC, − 5.8 mg/dL; TG, − 13.7 mg/dL). The weighted MD in HDL-C and TC contained significant heterogeneity (HDL-C, I2 = 45.1%; TC, I2 = 56.2%). When trials were limited to those involving moderate-intensity exercise (55%–69% of the maximum heart rate) or an exercise volume ≥ 150 min/week, the weighted MD in HDL-C, LDL-C, TC, and TG improved significantly and did not contain significant heterogeneity. Conclusions: The findings suggest that the ideal form of exercise to improve lipid and lipoprotein levels in East Asians is exercise of moderate-intensity and in a volume ≥ 150 min/week. The purpose of the current work was to review the effects of regular aerobic exercise on serum lipid and lipoprotein levels in East Asians using meta-analysis.AIMThe purpose of the current work was to review the effects of regular aerobic exercise on serum lipid and lipoprotein levels in East Asians using meta-analysis.The randomized controlled trials analyzed involved healthy adults who were East Asians with a mean age ≥40 years, an exercise group that only performed regular aerobic exercise, and a control group that did not carry out exercise-related intervention; the trials indicated mean high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), or triglyceride (TG). The mean difference (MD) was defined as the difference (mean value at post-intervention in the exercise group－mean value at baseline in the exercise group)－(mean value at post-intervention in the control group－mean value at baseline in the control group) in HDL-C, LDL-C, TC, and TG and was calculated for each trial. The weighted MD was calculated with a random-effects model.METHODSThe randomized controlled trials analyzed involved healthy adults who were East Asians with a mean age ≥40 years, an exercise group that only performed regular aerobic exercise, and a control group that did not carry out exercise-related intervention; the trials indicated mean high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), or triglyceride (TG). The mean difference (MD) was defined as the difference (mean value at post-intervention in the exercise group－mean value at baseline in the exercise group)－(mean value at post-intervention in the control group－mean value at baseline in the control group) in HDL-C, LDL-C, TC, and TG and was calculated for each trial. The weighted MD was calculated with a random-effects model.The meta-analysis examined 994 subjects in 25 studies. The weighted MD in HDL-C, TC, and TG improved significantly (HDL-C, 2.2 mg/dL; TC, －5.8 mg/dL; TG, －13.7 mg/dL). The weighted MD in HDL-C and TC contained significant heterogeneity (HDL-C, I2＝45.1%; TC, I2＝56.2%). When trials were limited to those involving moderate-intensity exercise (55%-69% of the maximum heart rate) or an exercise volume ≥150 min/week, the weighted MD in HDL-C, LDL-C, TC, and TG improved significantly and did not contain significant heterogeneity.RESULTSThe meta-analysis examined 994 subjects in 25 studies. The weighted MD in HDL-C, TC, and TG improved significantly (HDL-C, 2.2 mg/dL; TC, －5.8 mg/dL; TG, －13.7 mg/dL). The weighted MD in HDL-C and TC contained significant heterogeneity (HDL-C, I2＝45.1%; TC, I2＝56.2%). When trials were limited to those involving moderate-intensity exercise (55%-69% of the maximum heart rate) or an exercise volume ≥150 min/week, the weighted MD in HDL-C, LDL-C, TC, and TG improved significantly and did not contain significant heterogeneity.The findings suggest that the ideal form of exercise to improve lipid and lipoprotein levels in East Asians is exercise of moderate-intensity and in a volume ≥150 min/week.CONCLUSIONSThe findings suggest that the ideal form of exercise to improve lipid and lipoprotein levels in East Asians is exercise of moderate-intensity and in a volume ≥150 min/week. The purpose of the current work was to review the effects of regular aerobic exercise on serum lipid and lipoprotein levels in East Asians using meta-analysis. The randomized controlled trials analyzed involved healthy adults who were East Asians with a mean age ≥40 years, an exercise group that only performed regular aerobic exercise, and a control group that did not carry out exercise-related intervention; the trials indicated mean high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), or triglyceride (TG). The mean difference (MD) was defined as the difference (mean value at post-intervention in the exercise group－mean value at baseline in the exercise group)－(mean value at post-intervention in the control group－mean value at baseline in the control group) in HDL-C, LDL-C, TC, and TG and was calculated for each trial. The weighted MD was calculated with a random-effects model. The meta-analysis examined 994 subjects in 25 studies. The weighted MD in HDL-C, TC, and TG improved significantly (HDL-C, 2.2 mg/dL; TC, －5.8 mg/dL; TG, －13.7 mg/dL). The weighted MD in HDL-C and TC contained significant heterogeneity (HDL-C, I ＝45.1%; TC, I ＝56.2%). When trials were limited to those involving moderate-intensity exercise (55%-69% of the maximum heart rate) or an exercise volume ≥150 min/week, the weighted MD in HDL-C, LDL-C, TC, and TG improved significantly and did not contain significant heterogeneity. The findings suggest that the ideal form of exercise to improve lipid and lipoprotein levels in East Asians is exercise of moderate-intensity and in a volume ≥150 min/week. Aim: The purpose of the current work was to review the effects of regular aerobic exercise on serum lipid and lipoprotein levels in East Asians using meta-analysis. Methods: The randomized controlled trials analyzed involved healthy adults who were East Asians with a mean age ≥40 years, an exercise group that only performed regular aerobic exercise, and a control group that did not carry out exercise-related intervention; the trials indicated mean high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), or triglyceride (TG). The mean difference (MD) was defined as the difference (mean value at post-intervention in the exercise group－mean value at baseline in the exercise group)－(mean value at post-intervention in the control group－mean value at baseline in the control group) in HDL-C, LDL-C, TC, and TG and was calculated for each trial. The weighted MD was calculated with a random-effects model. Results: The meta-analysis examined 994 subjects in 25 studies. The weighted MD in HDL-C, TC, and TG improved significantly (HDL-C, 2.2 mg/dL; TC, －5.8 mg/dL; TG, －13.7 mg/dL). The weighted MD in HDL-C and TC contained significant heterogeneity (HDL-C, I2＝45.1%; TC, I2＝56.2%). When trials were limited to those involving moderate-intensity exercise (55%–69% of the maximum heart rate) or an exercise volume ≥150 min/week, the weighted MD in HDL-C, LDL-C, TC, and TG improved significantly and did not contain significant heterogeneity.Conclusions: The findings suggest that the ideal form of exercise to improve lipid and lipoprotein levels in East Asians is exercise of moderate-intensity and in a volume ≥150 min/week. [Aim:] The purpose of the current work was to review the effects of regular aerobic exercise on serum lipid and lipoprotein levels in East Asians using meta-analysis. [Methods:] The randomized controlled trials analyzed involved healthy adults who were East Asians with a mean age >-40 years, an exercise group that only performed regular aerobic exercise, and a control group that did not carry out exercise-related intervention; the trials indicated mean high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), or triglyceride (TG). The mean difference (MD) was defined as the difference (mean value at post-intervention in the exercise group - mean value at baseline in the exercise group) - (mean value at post-intervention in the control group - mean value at baseline in the control group) in HDL-C, LDL-C, TC, and TG and was calculated for each trial. The weighted MD was calculated with a random-effects model. [Results:] The meta-analysis examined 994 subjects in 25 studies. The weighted MD in HDL-C, TC, and TG improved significantly (HDL-C, 2.2 mg/dL; TC, -5.8 mg/dL; TG, -13.7 mg/dL). The weighted MD in HDL-C and TC contained significant heterogeneity (HDL-C, I2=45.1%; TC, I2=56.2%). When trials were limited to those involving moderate-intensity exercise (55%-69% of the maximum heart rate) or an exercise volume >-150 min/week, the weighted MD in HDL-C, LDL-C, TC, and TG improved significantly and did not contain significant heterogeneity. [Conclusions:] The findings suggest that the ideal form of exercise to improve lipid and lipoprotein levels in East Asians is exercise of moderate-intensity and in a volume >-150 min/week. |
| Author | Akazawa, Nobuhiko Igarashi, Yutaka Maeda, Seiji |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/30381613$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.5551/jat.37895 10.1055/s-0031-1271789 10.1055/s-0042-121605 10.1016/j.ypmed.2003.12.012 10.1001/archinte.167.10.999 10.1002/sim.1186 10.5551/jat.GL2017 10.1136/bjsm.2008.052126 10.1097/00005768-199806000-00032 10.5551/jat.34728 10.1136/bmj.g7647 10.1097/00000441-198904000-00004 10.1046/j.1440-1681.2003.03846.x 10.1210/jc.2012-1951 10.1161/JAHA.112.004473 10.1139/h2012-084 10.1194/jlr.M030213 10.1539/joh.41.76 10.7888/juoeh.34.297 10.1089/met.2012.0036 10.1249/00005768-197600820-00021 10.5551/jat.19356 10.1093/ajcn/77.5.1146 10.1111/j.0006-341X.2000.00455.x 10.1139/h2012-069 10.1080/10641963.2017.1384483 10.1111/cpf.12217 10.1007/BF00280883 10.1249/mss.0b013e3180616b27 10.1016/j.archger.2015.06.017 10.1161/01.HYP.33.1.591 10.1016/0895-4356(92)90054-Q 10.1016/j.clnu.2011.11.011 10.1081/CEH-120004234 10.5551/jat.37044 10.1589/jpts.26.1825 10.1155/2012/985902 10.3109/10641963.2015.1013115 10.1016/S0026-0495(99)90194-4 10.1016/j.ghir.2011.12.004 10.5551/jat.43851 10.7326/0003-4819-136-7-200204020-00006 10.2337/diacare.27.1.66 10.1136/bmj.315.7109.629 10.1089/jwh.2004.13.1148 10.1161/01.CIR.100.11.1194 10.1097/GME.0000000000000264 10.1016/S0895-7061(02)02273-2 10.1210/jc.2016-1650 10.1111/j.0197-3118.2005.03769.x 10.1016/0197-2456(86)90046-2 10.1097/00005768-200106001-00021 10.1291/hypres.27.947 |
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| References | 2) Health Service Division, Health Service Bureau, Ministry of Health, Labour and Welfare of Japan: National Health and Nutrition Survey. Tokyo, Japan: Statistical Surveys conducted by Ministry of Health, Labour and Welfare; 2016 43) Cho JK, Lee SH, Lee JY, and Kang HS: Randomized controlled trial of training intensity in adiposity. Int J Sports Med, 2011; 32: 468-475 51) Uchikawa Y, Nakamura C, Miyai N, Ito K, and Ishii A, Utsumi M, and Arita M: Effects of walking in sand-beach on novel risk factors of cardiovascular disease in metabolic syndrome - randomized control design. Heart, 2012; 44: 799-804 (Japanese 21) Higgins JPT and Green S (eds): Cochrane handbook for systematic reviews of interventions version 5.1.0. [updated March 2011]. London, UK: The Cochrane Collaboration; Available from http://handbook.cochrane.org 12) Kelley GA, Kelley KS, Roberts S, and Haskell W: Comparison of aerobic exercise, diet or both on lipids and lipoproteins in adults: a meta-analysis of randomized controlled trials. Clin Nutr, 2012; 31: 156-167 29) Haskell WL, Lee IM, Pate RR, Powell KE, Blair SN, Franklin BA, Macera CA, Heath GW, Thompson PD, and Bauman A; American College of Sports Medicine; American Heart Association: Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation, 2007; 116: 1081-1093 36) Sunami Y, Motoyama M, Kinoshita F, Mizooka Y, Sueta K, Matsunaga A, Sasaki J, Tanaka H, and Shindo M: Effects of low-intensity aerobic training on the high-density lipoprotein cholesterol concentration in healthy elderly subjects. Metabolism, 1999; 48: 984-988 56) Tan S, Wang J, Cao L, Guo Z, and Wang Y: Positive effect of exercise training at maximal fat oxidation intensity on body composition and lipid metabolism in overweight middle-aged women. Clin Physiol Funct Imaging, 2016; 36: 225-230 35) Higashi Y, Sasaki S, Sasaki N, Nakagawa K, Ueda T, Yoshimizu A, Kurisu S, Matsuura H, Kajiyama G, and Oshima T: Daily aerobic exercise improves reactive hyperemia in patients with essential hypertension. Hypertension, 1999; 33: 591-597 54) Nishida Y, Tanaka K, Hara M, Hirao N, Tanaka H, Tobina T, Ikeda M, Yamato H, and Ohta M: Effects of homebased bench step exercise on inflammatory cytokines and lipid profiles in elderly Japanese females: A randomized controlled trial. Arch Gerontol Geriatr, 2015; 61: 443-451 52) Kim DY and Jung SY: Effect of Aerobic Exercise on Risk Factors of Cardiovascular Disease and the Apolipoprotein B / Apolipoprotein A-1 Ratio in Obese Woman. J Phys Ther Sci, 2014; 26: 1825-1829 25) Kinoshita M, Yokote K, Arai H, Iida M, Ishigaki Y, Ishibashi S, Umemoto S, Egusa G, Ohmura H, Okamura T, Kihara S, Koba S, Saito I, Shoji T, Daida H, Tsukamoto K, Deguchi J, Dohi S, Dobashi K, Hamaguchi H, Hara M, Hiro T, Biro S, Fujioka Y, Maruyama C, Miyamoto Y, Murakami Y, Yokode M, Yoshida H, Rakugi H, Wakatsuki A, Yamashita S, and Committee for Epidemiology and Clinical Management of Atherosclerosis: Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017. J Atheroscler Thromb, 2018; 25: 846-984 32) Sasaki J, Urata H, Tanabe Y, Kinoshita A, Tanaka H, Shindo M, and Arakawa K: Mild exercise therapy increases serum high density lipoprotein 2 cholesterol levels in patients with essential hypertension. Am J Med Sci, 1989; 297: 220-223 13) Kelley GA, Kelley KS, and Tran ZV: Walking, lipids, and lipoproteins: a meta-analysis of randomized controlled trials. Prev Med, 2004; 38: 651-661 37) Tsai JC, Chang WY, Kao CC, Lu MS, Chen YJ, and Chan P: Beneficial effect on blood pressure and lipid profile by programmed exercise training in Taiwanese patients with mild hypertension. Clin Exp Hypertens, 2002; 24: 315-324 7) Nishimura K, Okamura T, Watanabe M, Nakai M, Takegami M, Higashiyama A, Kokubo Y, Okayama A, and Miyamoto Y: Predicting coronary heart disease using risk factor categories for a Japanese urban population, and comparison with the Framingham risk Score: the Suita study. J Atheroscler Thromb, 2014; 21: 784-798 42) Uchikawa Y, Miyai N, Ito K, Yabu M, Ishii A, Shiba M, Utsumi M, and Arita M: Effects of walking exercise on cardiovascular risk parameters and arterial stiffness in middle-aged and elder subjects. Jpn J Appl physiol, 2010; 40: 185-192 (Japanese 58) Takeno K, Tamura Y, Kawaguchi M, Kakehi S, Watanabe T, Funayama T, Furukawa Y, Kaga H, Yamamoto R, Kim M, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Taka H, Fujimura T, Sawada SS, Giacca A, Kanazawa A, Fujitani Y, Kawamori R, and Watada H: Relation between insulin sensitivity and metabolic abnormalities in Japanese men with BMI of 23-25 kg/m2. J Clin Endocrinol Metab, 2016; 101: 3676-3684 23) Follmann D, Elliott P, Suh I, and Cutler J: Variance imputation for overviews of clinical trials with continuous response. J Clin Epidemiol, 1992; 45: 769-773 31) Duval S and Tweedie R: Trim and fill: A simple funnelplot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics, 2000; 56: 455-463 63) Yu N, Ruan Y, Gao X, and Sun J: Systematic Review and Meta-Analysis of Randomized, Controlled Trials on the Effect of Exercise on Serum Leptin and Adiponectin in Overweight and Obese Individuals. Horm Metab Res, 2017; 49: 164-173 38) Tsai JC, Liu JC, Kao CC, Tomlinson B, Kao PF, Chen JW, and Chan P: Beneficial effects on blood pressure and lipid profile of programmed exercise training in subjects with white coat hypertension. Am J Hypertens, 2002; 15: 571-576 9) Mensink RP, Zock PL, Kester AD, and Katan MB: Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. Am J Clin Nutr, 2003; 77: 1146-1155 26) World Health Organization: Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Consultation. WHO Technical Report Series, 1995; 854 27) American College of Sports Medicine Position Stand: The recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness, and flexibility in healthy adults. Med Sci Sports Exerc, 1998; 30: 975-991 53) Zhang J, Chen G, Lu W, Yan X, Zhu S, Dai Y, Xi S, Yao C, and Bai W: Effects of physical exercise on healthrelated quality of life and blood lipids in perimenopausal women: a randomized placebo-controlled trial. Menopause, 2014; 21: 1269-1276 5) Usui T, Nagata M, Hata J, Mukai N, Hirakawa Y, Yoshida D, Kishimoto H, Kitazono T, Kiyohara Y, and Ninomiya T: Serum non-high-density lipoprotein cholesterol and risk of cardiovascular disease in community dwellers with chronic kidney disease: the Hisayama study. J Atheroscler Thromb, 2017; 24: 706-715 4) Wu TW, Hung CL, Liu CC, Wu YJ, Wang LY, and Yeh HI: Associations of cardiovascular risk factors with carotid intima-media thickness in middle-age adults and elders. J Atheroscler Thromb, 2017; 24: 677-686 33) Fukahori M, Aono H, Saito I, Ikebe T, and Ozawa H: Program of exercise training as total. health promotion plan and its evaluation. J Occup Health, 1999; 41: 76-82 14) Kelley GA, Kelley KS, and Tran ZV: Aerobic exercise and lipids and lipoproteins in women: a meta-analysis of randomized controlled trials. J Womens Health (Larchmt), 2004; 13: 1148-1164 50) Sugawara J and Maeda S: Effect of aerobic exercise training central arterial hemodynamics in postmenopausal women. Research-aid Report, 2012; 27: 108-117 (Japanese 57) Cornelissen VA and Smart NA: Exercise training for blood pressure: a systematic review and meta-analysis. J Am Heart Assoc, 2013; 2: e004473 1) Health Statistics Office, Director-General for Statistics and Information Policy, Ministry of Health, Labour and Welfare of Japan: Estimates of National Medical Care Expenditure, FY 2015. Tokyo, Japan: Statistical Surveys conducted by Ministry of Health, Labour and Welfare; 2017 24) Higgins JP and Thompson SG: Quantifying heterogeneity in a meta-analysis. Stat Med, 2002; 21: 1539-1558 6) Manita D, Yoshida H, and Hirowatari Y: Cholesterol levels of six fractionated serum lipoproteins and its relevance to coronary heart disease risk scores. J Atheroscler Thromb, 2017; 24: 928-939 22) DerSimonian R and Laird N: Meta-analysis in clinical trials. Control Clin Trials, 1986; 7: 177-188 41) Yoshizawa M, Maeda S, Miyaki A, Misono M, Saito Y, Tanabe K, Kuno S, and Ajisaka R: Effect of 12 weeks of moderate-intensity resistance training on arterial stiffness: a randomised controlled trial in women aged 32-59 years. Br J Sports Med, 2009; 43: 615-618 10) Leon AS and Sanchez OA: Response of blood lipids to exercise training alone or combined with dietary intervention. Med Sci Sports Exerc, 2001; 33: S502-515 49) Ohta M, Hirao N, Mori Y, Takigami C, Eguchi M, Tanaka H, Ikeda M, and Yamato H: Effects of bench step exercise on arterial stiffness in post-menopausal women: contribution of IGF-1 bioactivity and nitric oxide production. Growth Horm IGF Res, 2012; 22: 36-41 61) Izadi V, Farabad E, and Azadbakht L: Epidemiologic evidence on serum adiponectin level and lipid profile. Int J Prev Med, 2013; 4: 133-140 39) Tsuda K, Yoshikawa A, Kimura K, and Nishio I: Effects of mild aerobic physical exercise on membrane fluidity of erythrocytes in essential hypertension. Clin Exp Pharmacol Physiol, 2003; 30: 382-386 16) Kodama S, Tanaka S, Saito K, Shu M, Sone Y, Onitake F, Suzuki E, Shimano H, Yamamoto S, Kondo K, Ohashi Y, Yamada N, and Sone H: Effect of aerobic exercise training on serum levels of high-density lipoprotein cholesterol: a meta-analysis. Arch Intern Med, 2007; 167: 999-1008 30) Egger M, Davey Smith G, Schneider M, and Minder C: Bias in meta-analysis detected by a simple, graphical test. BMJ, 1997; 315: 629-634 48) Miyaki A, Maeda S, Choi Y, Akazawa N, Tanabe Y, and Ajisaka R: Habitual aerobic exercise increases plasma pentraxin 3 levels in middle-aged and elderly women. Appl Physiol Nutr Metab, 2012; 37: 907-911 62) 44 45 46 47 48 49 50 51 52 53 10 54 11 55 12 56 13 57 14 58 15 59 16 17 18 19 1 2 3 4 5 6 7 8 9 60 61 62 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 |
| References_xml | – reference: 20) University of York, Centre for reviews and dissemination: PROSPERO: International Prospective Register of Systematic Reviews. York, UK: University of York; Available from https://www.crd.york.ac.uk/prospero/ – reference: 58) Takeno K, Tamura Y, Kawaguchi M, Kakehi S, Watanabe T, Funayama T, Furukawa Y, Kaga H, Yamamoto R, Kim M, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Taka H, Fujimura T, Sawada SS, Giacca A, Kanazawa A, Fujitani Y, Kawamori R, and Watada H: Relation between insulin sensitivity and metabolic abnormalities in Japanese men with BMI of 23-25 kg/m2. J Clin Endocrinol Metab, 2016; 101: 3676-3684 – reference: 34) Higashi Y, Sasaki S, Kurisu S, Yoshimizu A, Sasaki N, Matsuura H, Kajiyama G, and Oshima T: Regular aerobic exercise augments endothelium-dependent vascular relaxation in normotensive as well as hypertensive subjects: role of endothelium-derived nitric oxide. Circulation, 1999; 100: 1194-1202 – reference: 33) Fukahori M, Aono H, Saito I, Ikebe T, and Ozawa H: Program of exercise training as total. health promotion plan and its evaluation. J Occup Health, 1999; 41: 76-82 – reference: 10) Leon AS and Sanchez OA: Response of blood lipids to exercise training alone or combined with dietary intervention. Med Sci Sports Exerc, 2001; 33: S502-515 – reference: 5) Usui T, Nagata M, Hata J, Mukai N, Hirakawa Y, Yoshida D, Kishimoto H, Kitazono T, Kiyohara Y, and Ninomiya T: Serum non-high-density lipoprotein cholesterol and risk of cardiovascular disease in community dwellers with chronic kidney disease: the Hisayama study. J Atheroscler Thromb, 2017; 24: 706-715 – reference: 8) Yu-Poth S, Zhao G, Etherton T, Naglak M, Jonnalagadda S, and Kris-Etherton PM: Effects of the National Cholesterol Education Program's Step Ⅰ and Step II dietary intervention programs on cardiovascular disease risk factors: a meta-analysis. Am J Clin Nutr, 1999; 69: 632-646 – reference: 21) Higgins JPT and Green S (eds): Cochrane handbook for systematic reviews of interventions version 5.1.0. [updated March 2011]. London, UK: The Cochrane Collaboration; Available from http://handbook.cochrane.org/ – reference: 59) McNeely MJ and Boyko EJ: Type 2 diabetes prevalence in Asian Americans: results of a national health survey. Diabetes Care, 2004; 27: 66-69 – reference: 29) Haskell WL, Lee IM, Pate RR, Powell KE, Blair SN, Franklin BA, Macera CA, Heath GW, Thompson PD, and Bauman A; American College of Sports Medicine; American Heart Association: Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation, 2007; 116: 1081-1093 – reference: 39) Tsuda K, Yoshikawa A, Kimura K, and Nishio I: Effects of mild aerobic physical exercise on membrane fluidity of erythrocytes in essential hypertension. Clin Exp Pharmacol Physiol, 2003; 30: 382-386 – reference: 31) Duval S and Tweedie R: Trim and fill: A simple funnelplot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics, 2000; 56: 455-463 – reference: 6) Manita D, Yoshida H, and Hirowatari Y: Cholesterol levels of six fractionated serum lipoproteins and its relevance to coronary heart disease risk scores. J Atheroscler Thromb, 2017; 24: 928-939 – reference: 48) Miyaki A, Maeda S, Choi Y, Akazawa N, Tanabe Y, and Ajisaka R: Habitual aerobic exercise increases plasma pentraxin 3 levels in middle-aged and elderly women. Appl Physiol Nutr Metab, 2012; 37: 907-911 – reference: 55) Ohta Y, Kawano Y, Minami J, Iwashima Y, Hayashi S, Yoshihara F, and Nakamura S: Effects of daily walking on office, home and 24-h blood pressure in hypertensive patients. Clin Exp Hypertens, 2015; 37: 433-437 – reference: 62) Belalcazar LM, Lang W, Haffner SM, Hoogeveen RC, Pi-Sunyer FX, Schwenke DC, Balasubramanyam A, Tracy RP, Kriska AP, Ballantyne CM, and Look AHEAD Research Group: Adiponectin and the mediation of HDL-cholesterol change with improved lifestyle: the Look AHEAD Study. J Lipid Res, 2012; 53: 2726-2733 – reference: 35) Higashi Y, Sasaki S, Sasaki N, Nakagawa K, Ueda T, Yoshimizu A, Kurisu S, Matsuura H, Kajiyama G, and Oshima T: Daily aerobic exercise improves reactive hyperemia in patients with essential hypertension. Hypertension, 1999; 33: 591-597 – reference: 63) Yu N, Ruan Y, Gao X, and Sun J: Systematic Review and Meta-Analysis of Randomized, Controlled Trials on the Effect of Exercise on Serum Leptin and Adiponectin in Overweight and Obese Individuals. Horm Metab Res, 2017; 49: 164-173 – reference: 36) Sunami Y, Motoyama M, Kinoshita F, Mizooka Y, Sueta K, Matsunaga A, Sasaki J, Tanaka H, and Shindo M: Effects of low-intensity aerobic training on the high-density lipoprotein cholesterol concentration in healthy elderly subjects. Metabolism, 1999; 48: 984-988 – reference: 32) Sasaki J, Urata H, Tanabe Y, Kinoshita A, Tanaka H, Shindo M, and Arakawa K: Mild exercise therapy increases serum high density lipoprotein 2 cholesterol levels in patients with essential hypertension. Am J Med Sci, 1989; 297: 220-223 – reference: 15) Kelley GA, Kelley KS, and Tran ZV: Exercise, lipids, and lipoproteins in older adults: a meta-analysis. Prev Cardiol, 2005; 8: 206-214 – reference: 3) Watanabe N, S Sawada S, Shimada K, Lee IM, Gando Y, Momma H, Kawakami R, Miyachi M, Hagi Y, Kinugawa C, Okamoto T, Tsukamoto K, N and Blair S: Relationship between cardiorespiratory fitness and non-high-density lipoprotein cholesterol: A cohort study. J Atheroscler Thromb, 2018; 25: 1196-1205 – reference: 16) Kodama S, Tanaka S, Saito K, Shu M, Sone Y, Onitake F, Suzuki E, Shimano H, Yamamoto S, Kondo K, Ohashi Y, Yamada N, and Sone H: Effect of aerobic exercise training on serum levels of high-density lipoprotein cholesterol: a meta-analysis. Arch Intern Med, 2007; 167: 999-1008 – reference: 57) Cornelissen VA and Smart NA: Exercise training for blood pressure: a systematic review and meta-analysis. J Am Heart Assoc, 2013; 2: e004473 – reference: 61) Izadi V, Farabad E, and Azadbakht L: Epidemiologic evidence on serum adiponectin level and lipid profile. Int J Prev Med, 2013; 4: 133-140 – reference: 7) Nishimura K, Okamura T, Watanabe M, Nakai M, Takegami M, Higashiyama A, Kokubo Y, Okayama A, and Miyamoto Y: Predicting coronary heart disease using risk factor categories for a Japanese urban population, and comparison with the Framingham risk Score: the Suita study. J Atheroscler Thromb, 2014; 21: 784-798 – reference: 51) Uchikawa Y, Nakamura C, Miyai N, Ito K, and Ishii A, Utsumi M, and Arita M: Effects of walking in sand-beach on novel risk factors of cardiovascular disease in metabolic syndrome - randomized control design. Heart, 2012; 44: 799-804 (Japanese) – reference: 41) Yoshizawa M, Maeda S, Miyaki A, Misono M, Saito Y, Tanabe K, Kuno S, and Ajisaka R: Effect of 12 weeks of moderate-intensity resistance training on arterial stiffness: a randomised controlled trial in women aged 32-59 years. Br J Sports Med, 2009; 43: 615-618 – reference: 44) Choi KM, Han KA, Ahn HJ, Hwang SY, Hong HC, Choi HY, Yang SJ, Yoo HJ, Baik SH, Choi DS, and Min KW: Effects of exercise on sRAGE levels and cardiometabolic risk factors in patients with type 2 diabetes: a randomized controlled trial. J Clin Endocrinol Metab, 2012; 97: 3751-3758 – reference: 25) Kinoshita M, Yokote K, Arai H, Iida M, Ishigaki Y, Ishibashi S, Umemoto S, Egusa G, Ohmura H, Okamura T, Kihara S, Koba S, Saito I, Shoji T, Daida H, Tsukamoto K, Deguchi J, Dohi S, Dobashi K, Hamaguchi H, Hara M, Hiro T, Biro S, Fujioka Y, Maruyama C, Miyamoto Y, Murakami Y, Yokode M, Yoshida H, Rakugi H, Wakatsuki A, Yamashita S, and Committee for Epidemiology and Clinical Management of Atherosclerosis: Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017. J Atheroscler Thromb, 2018; 25: 846-984 – reference: 45) Eguchi Y, Ohta M, Inoue T, Honda T, Morita Y, Konno Y, and Yamato H: Effects of transitory stimulation interval exercise on physical function: a randomized controlled pilot study among Japanese Subjects. J UOEH, 2012; 34: 297-308 – reference: 46) Kim JW and Kim DY: Effects of aerobic exercise training on serum sex hormone binding globulin, body fat index, and metabolic syndrome factors in obese postmenopausal women. Metab Syndr Relat Disord, 2012; 10: 452-457 – reference: 27) American College of Sports Medicine Position Stand: The recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness, and flexibility in healthy adults. Med Sci Sports Exerc, 1998; 30: 975-991 – reference: 2) Health Service Division, Health Service Bureau, Ministry of Health, Labour and Welfare of Japan: National Health and Nutrition Survey. Tokyo, Japan: Statistical Surveys conducted by Ministry of Health, Labour and Welfare; 2016 – reference: 4) Wu TW, Hung CL, Liu CC, Wu YJ, Wang LY, and Yeh HI: Associations of cardiovascular risk factors with carotid intima-media thickness in middle-age adults and elders. J Atheroscler Thromb, 2017; 24: 677-686 – reference: 43) Cho JK, Lee SH, Lee JY, and Kang HS: Randomized controlled trial of training intensity in adiposity. Int J Sports Med, 2011; 32: 468-475 – reference: 12) Kelley GA, Kelley KS, Roberts S, and Haskell W: Comparison of aerobic exercise, diet or both on lipids and lipoproteins in adults: a meta-analysis of randomized controlled trials. Clin Nutr, 2012; 31: 156-167 – reference: 56) Tan S, Wang J, Cao L, Guo Z, and Wang Y: Positive effect of exercise training at maximal fat oxidation intensity on body composition and lipid metabolism in overweight middle-aged women. Clin Physiol Funct Imaging, 2016; 36: 225-230 – reference: 19) Shamseer L, Moher D, Clarke M, Ghersi D, Liberati A, Petticrew M, Shekelle P, Stewart LA, and PRISMA-P Group: Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ, 2015; 349: g7647 – reference: 50) Sugawara J and Maeda S: Effect of aerobic exercise training central arterial hemodynamics in postmenopausal women. Research-aid Report, 2012; 27: 108-117 (Japanese) – reference: 13) Kelley GA, Kelley KS, and Tran ZV: Walking, lipids, and lipoproteins: a meta-analysis of randomized controlled trials. Prev Med, 2004; 38: 651-661 – reference: 42) Uchikawa Y, Miyai N, Ito K, Yabu M, Ishii A, Shiba M, Utsumi M, and Arita M: Effects of walking exercise on cardiovascular risk parameters and arterial stiffness in middle-aged and elder subjects. Jpn J Appl physiol, 2010; 40: 185-192 (Japanese) – reference: 53) Zhang J, Chen G, Lu W, Yan X, Zhu S, Dai Y, Xi S, Yao C, and Bai W: Effects of physical exercise on healthrelated quality of life and blood lipids in perimenopausal women: a randomized placebo-controlled trial. Menopause, 2014; 21: 1269-1276 – reference: 18) Igarashi Y, Akazawa N, and Maeda S: Regular aerobic exercise and blood pressure in East Asians: A meta-analysis of randomized controlled trials. Clin Exp hypertens, 2018; 40: 378-389 – reference: 26) World Health Organization: Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Consultation. WHO Technical Report Series, 1995; 854 – reference: 52) Kim DY and Jung SY: Effect of Aerobic Exercise on Risk Factors of Cardiovascular Disease and the Apolipoprotein B / Apolipoprotein A-1 Ratio in Obese Woman. J Phys Ther Sci, 2014; 26: 1825-1829 – reference: 60) Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, and Turner RC: Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia, 1985; 28: 412-419 – reference: 11) Kelley GA, Kelley KS, Roberts S, and Haskell W: Combined effects of aerobic exercise and diet on lipids and lipoproteins in overweight and obese adults: a meta-analysis.J Obes, 2012; 2012: 985902 – reference: 38) Tsai JC, Liu JC, Kao CC, Tomlinson B, Kao PF, Chen JW, and Chan P: Beneficial effects on blood pressure and lipid profile of programmed exercise training in subjects with white coat hypertension. Am J Hypertens, 2002; 15: 571-576 – reference: 17) Whelton SP, Chin A, Xin X, and He J: Effect of aerobic exercise on blood pressure: a meta-analysis of randomized, control trial. Ann Intern Med, 2002; 136: 493-503 – reference: 24) Higgins JP and Thompson SG: Quantifying heterogeneity in a meta-analysis. Stat Med, 2002; 21: 1539-1558 – reference: 9) Mensink RP, Zock PL, Kester AD, and Katan MB: Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. Am J Clin Nutr, 2003; 77: 1146-1155 – reference: 22) DerSimonian R and Laird N: Meta-analysis in clinical trials. Control Clin Trials, 1986; 7: 177-188 – reference: 28) Londeree BR and Ames SA: Trend analysis of the % VO2 max-HR regression: Med Sci Sports, 1976; 8: 123-125 – reference: 14) Kelley GA, Kelley KS, and Tran ZV: Aerobic exercise and lipids and lipoproteins in women: a meta-analysis of randomized controlled trials. J Womens Health (Larchmt), 2004; 13: 1148-1164 – reference: 1) Health Statistics Office, Director-General for Statistics and Information Policy, Ministry of Health, Labour and Welfare of Japan: Estimates of National Medical Care Expenditure, FY 2015. Tokyo, Japan: Statistical Surveys conducted by Ministry of Health, Labour and Welfare; 2017 – reference: 49) Ohta M, Hirao N, Mori Y, Takigami C, Eguchi M, Tanaka H, Ikeda M, and Yamato H: Effects of bench step exercise on arterial stiffness in post-menopausal women: contribution of IGF-1 bioactivity and nitric oxide production. Growth Horm IGF Res, 2012; 22: 36-41 – reference: 30) Egger M, Davey Smith G, Schneider M, and Minder C: Bias in meta-analysis detected by a simple, graphical test. BMJ, 1997; 315: 629-634 – reference: 47) Lee MG, Park KS, Kim DU, Choi SM, and Kim HJ: Effects of high-intensity exercise training on body composition, abdominal fat loss, and cardiorespiratory fitness in middle-aged Korean females. Appl Physiol Nutr Metab, 2012; 37: 1019-1027 – reference: 54) Nishida Y, Tanaka K, Hara M, Hirao N, Tanaka H, Tobina T, Ikeda M, Yamato H, and Ohta M: Effects of homebased bench step exercise on inflammatory cytokines and lipid profiles in elderly Japanese females: A randomized controlled trial. Arch Gerontol Geriatr, 2015; 61: 443-451 – reference: 40) Maeda S, Tanabe T, Otsuki T, Sugawara J, Iemitsu M, Miyauchi T, Kuno S, Ajisaka R, and Matsuda M: Moderate regular exercise increases basal production of nitric oxide in elderly women. Hypertens Res, 2004; 27: 947-953 – reference: 37) Tsai JC, Chang WY, Kao CC, Lu MS, Chen YJ, and Chan P: Beneficial effect on blood pressure and lipid profile by programmed exercise training in Taiwanese patients with mild hypertension. Clin Exp Hypertens, 2002; 24: 315-324 – reference: 23) Follmann D, Elliott P, Suh I, and Cutler J: Variance imputation for overviews of clinical trials with continuous response. J Clin Epidemiol, 1992; 45: 769-773 – ident: 2 – ident: 4 doi: 10.5551/jat.37895 – ident: 42 doi: 10.1055/s-0031-1271789 – ident: 62 doi: 10.1055/s-0042-121605 – ident: 12 doi: 10.1016/j.ypmed.2003.12.012 – ident: 15 doi: 10.1001/archinte.167.10.999 – ident: 23 doi: 10.1002/sim.1186 – ident: 24 doi: 10.5551/jat.GL2017 – ident: 40 doi: 10.1136/bjsm.2008.052126 – ident: 26 doi: 10.1097/00005768-199806000-00032 – ident: 6 doi: 10.5551/jat.34728 – ident: 18 doi: 10.1136/bmj.g7647 – ident: 31 doi: 10.1097/00000441-198904000-00004 – ident: 38 doi: 10.1046/j.1440-1681.2003.03846.x – ident: 43 doi: 10.1210/jc.2012-1951 – ident: 56 doi: 10.1161/JAHA.112.004473 – ident: 60 – ident: 46 doi: 10.1139/h2012-084 – ident: 49 – ident: 41 – ident: 61 doi: 10.1194/jlr.M030213 – ident: 32 doi: 10.1539/joh.41.76 – ident: 44 doi: 10.7888/juoeh.34.297 – ident: 45 doi: 10.1089/met.2012.0036 – ident: 27 doi: 10.1249/00005768-197600820-00021 – ident: 1 – ident: 7 doi: 10.5551/jat.19356 – ident: 8 doi: 10.1093/ajcn/77.5.1146 – ident: 30 doi: 10.1111/j.0006-341X.2000.00455.x – ident: 47 doi: 10.1139/h2012-069 – ident: 17 doi: 10.1080/10641963.2017.1384483 – ident: 55 doi: 10.1111/cpf.12217 – ident: 59 doi: 10.1007/BF00280883 – ident: 28 doi: 10.1249/mss.0b013e3180616b27 – ident: 53 doi: 10.1016/j.archger.2015.06.017 – ident: 50 – ident: 34 doi: 10.1161/01.HYP.33.1.591 – ident: 22 doi: 10.1016/0895-4356(92)90054-Q – ident: 11 doi: 10.1016/j.clnu.2011.11.011 – ident: 36 doi: 10.1081/CEH-120004234 – ident: 5 doi: 10.5551/jat.37044 – ident: 51 doi: 10.1589/jpts.26.1825 – ident: 10 doi: 10.1155/2012/985902 – ident: 54 doi: 10.3109/10641963.2015.1013115 – ident: 35 doi: 10.1016/S0026-0495(99)90194-4 – ident: 48 doi: 10.1016/j.ghir.2011.12.004 – ident: 3 doi: 10.5551/jat.43851 – ident: 16 doi: 10.7326/0003-4819-136-7-200204020-00006 – ident: 58 doi: 10.2337/diacare.27.1.66 – ident: 29 doi: 10.1136/bmj.315.7109.629 – ident: 13 doi: 10.1089/jwh.2004.13.1148 – ident: 20 – ident: 33 doi: 10.1161/01.CIR.100.11.1194 – ident: 52 doi: 10.1097/GME.0000000000000264 – ident: 37 doi: 10.1016/S0895-7061(02)02273-2 – ident: 57 doi: 10.1210/jc.2016-1650 – ident: 19 – ident: 14 doi: 10.1111/j.0197-3118.2005.03769.x – ident: 21 doi: 10.1016/0197-2456(86)90046-2 – ident: 9 doi: 10.1097/00005768-200106001-00021 – ident: 39 doi: 10.1291/hypres.27.947 – ident: 25 |
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| Title | Effects of Aerobic Exercise Alone on Lipids in Healthy East Asians: A Systematic Review and Meta-Analysis |
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