Deregulation of sphingolipid metabolism in Alzheimer's disease - He, Xingxuan; Huang, Yu; Li, Bin; Gong, Cheng-Xin; Schuchman, Edward H. (Neurobiology of aging, 2010)
Keywords: Acid Ceramidase - metabolism; Aged; Alzheimer Disease - metabolism; Alzheimer's disease; Amyloid beta-Peptides - metabolism; Animals; Apoptosis - physiology; Biological and medical sciences; Brain - metabolism; Cells, Cultured; Ceramidases; Ceramide; Ceramides - metabolism; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Development. Senescence. Regeneration. Transplantation; Fundamental and applied biological sciences. Psychology; Human brain; Humans; Internal Medicine; Lysophospholipids - metabolism; Medical sciences; Neurology; Neurons; Neurons - metabolism; Phosphorylation; Rats; Sphingolipids - metabolism; Sphingomyelin; Sphingomyelin Phosphodiesterase - metabolism; Sphingomyelinases; Sphingomyelins - metabolism; Sphingosine - analogs & derivatives; Sphingosine - metabolism; Sphingosine-1-phosphate; tau Proteins - metabolism; Vertebrates: nervous system and sense organs; Neurons; Ceramidases; Sphingosine-1-phosphate; Human brain; Sphingomyelin; Ceramide; Sphingomyelinases; Alzheimer's disease; Human; Nervous system diseases; Senescence; Enzyme; Alzheimer disease; Central nervous system; Metabolism; Ceramidase; Cerebral disorder; Encephalon; Neuron; Central nervous system disease; Hydrolases; Degenerative disease