Cold‐inducible RNA‐binding protein promotes the development of liver cancer - Sakurai, Toshiharu; Yada, Norihisa; Watanabe, Tomohiro; Arizumi, Tadaaki; Hagiwara, Satoru; Ueshima, Kazuomi; Nishida, Naoshi; Fujita, Jun; Kudo, Masatoshi (Cancer science, 2015)
Keywords: AC133 Antigen; Animal models; Animals; Antigens, CD - biosynthesis; Antioxidants; Antioxidants - pharmacology; Butylated hydroxyanisole; Butylated Hydroxyanisole - pharmacology; Carcinoma, Hepatocellular - genetics; CD133; Cell Transformation, Neoplastic - genetics; Cold; Drinking water; Glycoproteins - biosynthesis; HCC; Hepatitis; Hepatocellular carcinoma; Humans; Hypotheses; Hypoxia; Inflammation; Interleukin-1beta - biosynthesis; Interleukin-6 - biosynthesis; Kupffer cells; Kupffer Cells - metabolism; Liver - pathology; Liver cancer; Liver cirrhosis; Liver diseases; Liver Neoplasms - genetics; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Recurrence, Local - pathology; Neoplastic Stem Cells - pathology; Original; Oxidative stress; Oxidative Stress - genetics; Peptides; Phosphorylation - drug effects; Proteins; Reactive oxygen species; Reactive Oxygen Species - metabolism; recurrence; Ribonucleic acid; RNA; RNA-Binding Proteins - genetics; RNA-Binding Proteins - metabolism; ROS; SOXB1 Transcription Factors - biosynthesis; Stat3 protein; STAT3 Transcription Factor - metabolism; stem cell; Stem cells; Surveillance; Thioacetamide; Thioacetamide - pharmacology; Tissue Fixation; Transcription; Tumor necrosis factor-TNF; Tumorigenesis; Tumors; United States--US; Japan; recurrence; HCC; stem cell; ROS; CD133