The autocrine loop of ALK receptor and ALKAL2 ligand is an actionable target in consensus molecular subtype 1 colon cancer - Mazzeschi, Martina; Sgarzi, Michela; Romaniello, Donatella; Gelfo, Valerio; Cavallo, Carola; Ambrosi, Francesca; Morselli, Alessandra; Miano, Carmen; Laprovitera, Noemi; Girone, Cinzia; Ferracin, Manuela; Santi, Spartaco; et al. (Journal of experimental & clinical cancer research, 2022)
Keywords: activation; AKT; ALK; ALKAL2; anaplastic lymphoma kinase; Anaplastic Lymphoma Kinase - genetics; Animals; Apoptosis; Biomedical and Life Sciences; Biomedicine; Cancer and Oncology; Cancer och onkologi; Cancer Research; Cancer therapies; CMS1; Colon cancer; Colon Cancer therapy; Colonic Neoplasms - genetics; Colorectal cancer; Cytokines - genetics; Experiments; Gene amplification; Humans; Hydrogels; Immunology; Kinases; Lasers; Ligands; lung-cancer; Medical prognosis; Mice; Microscopy; Neoplasm Recurrence, Local; Non-Hodgkin's lymphomas; Oncology; Patients; Phosphorylation; Polymerization; poor-prognosis; Signalling; Software; Spheroids; tyrosine kinase; United States--US; ALK; 3D; Colon Cancer therapy; CMS1; ALKAL2; AKT; Signalling