APC-activated long noncoding RNA inhibits colorectal carcinoma pathogenesis through reduction of exosome production - Wang, Feng-Wei; Cao, Chen-Hui; Han, Kai; Zhao, Yong-Xiang; Cai, Mu-Yan; Xiang, Zhi-Cheng; Zhang, Jia-Xing; Chen, Jie-Wei; Zhong, Li-Ping; Huang, Yong; Zhou, Su-Fang; Jin, Xiao-Han; et al. (The Journal of clinical investigation, 2019)
Keywords: Adenomatous polyposis coli; Adenomatous Polyposis Coli Protein - genetics; Adenomatous Polyposis Coli Protein - metabolism; Angiogenesis; Animals; Antisense RNA; Apoptosis; Biomedical research; Cancer metastasis; Cancer patients; Cancer therapies; Carcinoma; Care and treatment; Cell adhesion & migration; Cell cycle; Cell growth; Cell migration; Cell proliferation; Cell Proliferation - genetics; Colorectal cancer; Colorectal carcinoma; Colorectal Neoplasms - genetics; Colorectal Neoplasms - metabolism; Colorectal Neoplasms - pathology; Development and progression; DNA microarrays; Drug development; Endothelial cells; Endothelium; Exosomes; Exosomes - genetics; Exosomes - metabolism; Exosomes - pathology; Familial polyposis; Gene expression; Gene Expression Regulation, Neoplastic; Gene mutation; Genes; Genetic aspects; Genetic disorders; HCT116 Cells; Health aspects; Humans; Kinases; Lymph nodes; MAP kinase; MAP Kinase Signaling System; Medical prognosis; Messenger RNA; Metastases; Metastasis; Mice; Mice, Nude; mRNA; Mutation; Pathogenesis; Patients; Phosphatase; Phosphorylation; Polyposis coli; Polyps; Proteins; RNA; RNA, Long Noncoding - biosynthesis; RNA, Long Noncoding - genetics; RNA, Neoplasm - biosynthesis; RNA, Neoplasm - genetics; Tumorigenesis; Tumors; Wnt protein; Wnt1 Protein - genetics; Wnt1 Protein - metabolism; Oncology; Cell migration/adhesion; Colorectal cancer; Gastroenterology