Incidental germline findings during molecular profiling of tumor tissues for precision oncology: molecular survey and methodological obstacles - Lebedeva, Alexandra; Shaykhutdinova, Yulia; Seriak, Daria; Ignatova, Ekaterina; Rozhavskaya, Ekaterina; Vardhan, Divyasphoorthi; Manicka, Sofia; Sharova, Margarita; Grigoreva, Tatiana; Baranova, Ancha; Mileyko, Vladislav; Ivanov, Maxim (Journal of translational medicine, 2022)
Keywords: Algorithms; Biomedical and Life Sciences; Biomedicine; Cancer; Cancer patients; Colorectal cancer; Computational Modelling and Epidemiology; Computer applications; Data analysis; Decision making; Diagnosis; Disease; DNA sequencing; Female; Genetic aspects; Genetic counseling; Genetic disorders; Germ Cells; Germ-Line Mutation - genetics; Health aspects; High-Throughput Nucleotide Sequencing; Humans; Lung cancer; Male; Medicine/Public Health; Middle Aged; Mutation; Neoplasms - pathology; Next-generation sequencing; Nucleotide sequencing; Oncology; Pancreatic cancer; Pathogenicity; Patients; Population; Precision Medicine; Software; Tumors; Russia