Tunable phenotypic variability through an autoregulatory alternative sigma factor circuit - Schwall, Christian P; Loman, Torkel E; Martins, Bruno M C; Cortijo, Sandra; Villava, Casandra; Kusmartsev, Vassili; Livesey, Toby; Saez, Teresa; Locke, James C W (Molecular systems biology, 2021)
Keywords: Bacillus subtilis; Bacillus subtilis - genetics; Bacteria; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Biological Variation, Population; Circuits; EMBO23; Environmental conditions; Environmental history; Gene expression; Gene Expression Regulation, Bacterial; Genetic variability; Heterogeneity; Homeostasis; Humans; Iterative methods; Life Sciences; Lysozyme; microbial systems biology; Microfluidics; Microscopy; Operon - genetics; Perturbation; Populations; Proteins; RNA polymerase; Sigma factor; Sigma Factor - genetics; Sigma Factor - metabolism; Signal transduction; single‐cell time‐lapse microscopy; stochastic gene expression; Stress; stress priming; Transcription; Variability; microbial systems biology; stochastic gene expression; stress priming; single‐cell time‐lapse microscopy; single-cell time-lapse microscopy; Bacillus subtilis; Virology & Host Pathogen Interaction; stress priming Subject Category Microbiology; stress primingphenoty