Schwann cells ER-associated degradation contributes to myelin maintenance in adult nerves and limits demyelination in CMT1B mice - Volpi, Vera G.; Ferri, Cinzia; Fregno, Ilaria; Del Carro, Ubaldo; Bianchi, Francesca; Scapin, Cristina; Pettinato, Emanuela; Solda, Tatiana; Feltri, M. Laura; Molinari, Maurizio; Wrabetz, Lawrence; D’Antonio, Maurizio (PLoS genetics, 2019)
Keywords: Age; Aging; Animals; Biochemistry; Biology; Biomarkers; Cell Line; Charcot-Marie-Tooth disease; Clonal deletion; Demyelinating Diseases - genetics; Demyelinating Diseases - metabolism; Demyelinating Diseases - pathology; Demyelination; Displays (Marketing); Endoplasmic reticulum; Endoplasmic Reticulum-Associated Degradation; Fluorescent Antibody Technique; Gene deletion; Gene Expression Profiling; Genetic disorders; Glucosamine; Glycoproteins; Homeostasis; Humans; Hypotheses; Kinases; Medicine; Mice; Mutation; Myelin P0 protein; Myelin proteins; Myelin Sheath - metabolism; Myelination; N-Acetyl-D-glucosamine; N-Acetylglucosamine; Nervous system; Neurology; Neurons; Neuropathy; Neurosciences; Peripheral nerves; Peripheral Nerves - metabolism; Peripheral Nerves - ultrastructure; Peripheral neuropathy; Physiological aspects; Proteasomes; Protein folding; Proteins; Quality control; Schwann cells; Schwann Cells - metabolism; Sciatic Nerve - metabolism; Serine; Stress response; Tetracyclines; New York; Italy; United States--US; Switzerland