Childhood adversity impacts on brain subcortical structures relevant to depression
Childhood adversity plays an important role for development of major depressive disorder (MDD). There are differences in subcortical brain structures between patients with MDD and healthy controls, but the specific impact of childhood adversity on such structures in MDD remains unclear. Thus, aim of...
Saved in:
| Published in | Journal of psychiatric research Vol. 86; pp. 58 - 65 |
|---|---|
| Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Elsevier Ltd
01.03.2017
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0022-3956 1879-1379 |
| DOI | 10.1016/j.jpsychires.2016.11.010 |
Cover
| Abstract | Childhood adversity plays an important role for development of major depressive disorder (MDD). There are differences in subcortical brain structures between patients with MDD and healthy controls, but the specific impact of childhood adversity on such structures in MDD remains unclear. Thus, aim of the present study was to investigate whether childhood adversity is associated with subcortical volumes and how it interacts with a diagnosis of MDD and sex. Within the ENIGMA-MDD network, nine university partner sites, which assessed childhood adversity and magnetic resonance imaging in patients with MDD and controls, took part in the current joint mega-analysis. In this largest effort world-wide to identify subcortical brain structure differences related to childhood adversity, 3036 participants were analyzed for subcortical brain volumes using FreeSurfer. A significant interaction was evident between childhood adversity, MDD diagnosis, sex, and region. Increased exposure to childhood adversity was associated with smaller caudate volumes in females independent of MDD. All subcategories of childhood adversity were negatively associated with caudate volumes in females - in particular emotional neglect and physical neglect (independently from age, ICV, imaging site and MDD diagnosis). There was no interaction effect between childhood adversity and MDD diagnosis on subcortical brain volumes. Childhood adversity is one of the contributors to brain structural abnormalities. It is associated with subcortical brain abnormalities that are relevant to psychiatric disorders such as depression. |
|---|---|
| AbstractList | Childhood adversity plays an important role for development of major depressive disorder (MDD). There are differences in subcortical brain structures between patients with MDD and healthy controls, but the specific impact of childhood adversity on such structures in MDD remains unclear. Thus, aim of the present study was to investigate whether childhood adversity is associated with subcortical volumes and how it interacts with a diagnosis of MDD and sex. Within the ENIGMA-MDD network, nine university partner sites, which assessed childhood adversity and magnetic resonance imaging in patients with MDD and controls, took part in the current joint mega-analysis. In this largest effort world-wide to identify subcortical brain structure differences related to childhood adversity, 3036 participants were analyzed for subcortical brain volumes using FreeSurfer. A significant interaction was evident between childhood adversity, MDD diagnosis, sex, and region. Increased exposure to childhood adversity was associated with smaller caudate volumes in females independent of MDD. All subcategories of childhood adversity were negatively associated with caudate volumes in females - in particular emotional neglect and physical neglect (independently from age, ICV, imaging site and MDD diagnosis). There was no interaction effect between childhood adversity and MDD diagnosis on subcortical brain volumes. Childhood adversity is one of the contributors to brain structural abnormalities. It is associated with subcortical brain abnormalities that are relevant to psychiatric disorders such as depression. Abstract Childhood adversity plays an important role for development of major depressive disorder (MDD). There are differences in subcortical brain structures between patients with MDD and healthy controls, but the specific impact of childhood adversity on such structures in MDD remains unclear. Thus, aim of the present study was to investigate whether childhood adversity is associated with subcortical volumes and how it interacts with a diagnosis of MDD and sex. Within the ENIGMA-MDD network, nine university partner sites, which assessed childhood adversity and magnetic resonance imaging in patients with MDD and controls, took part in the current joint mega-analysis. In this largest effort world-wide to identify subcortical brain structure differences related to childhood adversity, 3036 participants were analyzed for subcortical brain volumes using FreeSurfer. A significant interaction was evident between childhood adversity, MDD diagnosis, sex, and region. Increased exposure to childhood adversity was associated with smaller caudate volumes in females independent of MDD. All subcategories of childhood adversity were negatively associated with caudate volumes in females - in particular emotional neglect and physical neglect (independently from age, ICV, imaging site and MDD diagnosis). There was no interaction effect between childhood adversity and MDD diagnosis on subcortical brain volumes. Childhood adversity is one of the contributors to brain structural abnormalities. It is associated with subcortical brain abnormalities that are relevant to psychiatric disorders such as depression. Childhood adversity plays an important role for development of major depressive disorder (MDD). There are differences in subcortical brain structures between patients with MDD and healthy controls, but the specific impact of childhood adversity on such structures in MDD remains unclear. Thus, aim of the present study was to investigate whether childhood adversity is associated with subcortical volumes and how it interacts with a diagnosis of MDD and sex. Within the ENIGMA-MDD network, nine university partner sites, which assessed childhood adversity and magnetic resonance imaging in patients with MDD and controls, took part in the current joint mega-analysis. In this largest effort world-wide to identify subcortical brain structure differences related to childhood adversity, 3036 participants were analyzed for subcortical brain volumes using FreeSurfer. A significant interaction was evident between childhood adversity, MDD diagnosis, sex, and region. Increased exposure to childhood adversity was associated with smaller caudate volumes in females independent of MDD. All subcategories of childhood adversity were negatively associated with caudate volumes in females - in particular emotional neglect and physical neglect (independently from age, ICV, imaging site and MDD diagnosis). There was no interaction effect between childhood adversity and MDD diagnosis on subcortical brain volumes. Childhood adversity is one of the contributors to brain structural abnormalities. It is associated with subcortical brain abnormalities that are relevant to psychiatric disorders such as depression. |
| Author | Lagopoulos, Jim Vuletic, Daniella Frodl, Thomas Tozzi, Leonardo Völzke, Henry Schnell, Knut Dobrowolny, Henrik Carballedo, Angela Jahanshad, Neda Hatton, Sean N. Grotegerd, Dominik Stein, Dan J. Veltman, Dick J. Thompson, Paul M. Block, Andrea Konrad, Carsten Uhlmann, Anne Schramm, Elisabeth Kugel, Harald Hibar, Derrek P. Schmaal, Lianne van Erp, Theo G.M. Arolt, Volker Hickie, Ian B. Walter, Henrik Dannlowski, Udo Frey, Eva Maria van Tol, Marie-Jose van der Wee, Nic J.A. Brooks, Samantha J. Grabe, Hans J. Zurowski, Bartosz Wittfeld, Katharina Veer, Ilya M. Janowitz, Deborah Baune, Bernhard T. Penninx, Brenda W.J.H. Hegenscheid, Katrin |
| AuthorAffiliation | a Department of Psychiatry and Psychotherapy, Otto von Guericke University of Magdeburg, Germany e Department of Psychiatry and Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands z Department of Psychiatry, Leiden Institute for Brain and Cognition and Leiden Center for Translational Neuroscience, Leiden, The Netherlands y Department of Psychiatry, University of Marburg, Germany r Department of Clinical Radiology, University of Münster, Germany ab Orygen, The National Centre of Excellence in Youth Mental Health, Melbourne, Australia u Department of Psychiatry and Psychotherapy, Agaplesion Diakoniklinikum, Rotenburg, Germany ad Sociology of Physical Activity and Health, Department of Health Sciences, University of Potsdam, Germany b Department of Psychiatry, University of Dublin, Trinity College, Dublin, Ireland m Trinity College Institute of Neuroscience, Trinity College Dublin, Ireland g Imaging Genetics Center, Department of Neurology, Keck School of Medicin |
| AuthorAffiliation_xml | – name: d German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, Germany – name: x Discipline of Psychiatry, School of Medicine, University of Adelaide, SA 5005 Adelaide, Australia – name: k Brain and Mind Centre, University of Sydney, Camperdown, Australia – name: s Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Germany – name: e Department of Psychiatry and Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands – name: m Trinity College Institute of Neuroscience, Trinity College Dublin, Ireland – name: i Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Germany – name: n Department of Psychiatry and Mental Health, University of Cape Town, South Africa – name: y Department of Psychiatry, University of Marburg, Germany – name: ac Centre for Youth Mental Health, The University of Melbourne, Melbourne, Australia – name: ae Sunshine Coast Mind and Neuroscience – Thompson Institute, University of The Sunshine Coast, QLD, Australia – name: f Department of Psychiatry and Human Behavior, University of California, Irvine, CA, USA – name: t Psychiatric University Clinic, Basel, Switzerland – name: z Department of Psychiatry, Leiden Institute for Brain and Cognition and Leiden Center for Translational Neuroscience, Leiden, The Netherlands – name: aa Department of Neuroscience, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands – name: o Charité Universitätsmedizin Berlin, Department of Psychiatry and Psychotherapy, Division of Mind and Brain Research, Berlin, Germany – name: g Imaging Genetics Center, Department of Neurology, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA – name: j Institute for Community Medicine, University Medicine Greifswald, Germany – name: p Department of General Psychiatry, University Hospital Heidelberg, Germany – name: l Department of Psychiatry, University of Regensburg, Regensburg, Germany – name: h Helios Hospital Stralsund, Germany – name: q Department of Psychiatry and Psychotherapy, University of Münster, Germany – name: u Department of Psychiatry and Psychotherapy, Agaplesion Diakoniklinikum, Rotenburg, Germany – name: ad Sociology of Physical Activity and Health, Department of Health Sciences, University of Potsdam, Germany – name: b Department of Psychiatry, University of Dublin, Trinity College, Dublin, Ireland – name: c Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Germany – name: ab Orygen, The National Centre of Excellence in Youth Mental Health, Melbourne, Australia – name: r Department of Clinical Radiology, University of Münster, Germany – name: a Department of Psychiatry and Psychotherapy, Otto von Guericke University of Magdeburg, Germany – name: v Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Germany – name: w Center for Integrative Psychiatry, University of Lübeck, Lübeck, Germany |
| Author_xml | – sequence: 1 givenname: Thomas surname: Frodl fullname: Frodl, Thomas email: Thomas.Frodl@med.ovgu.de organization: Department of Psychiatry and Psychotherapy, Otto von Guericke University of Magdeburg, Germany – sequence: 2 givenname: Deborah surname: Janowitz fullname: Janowitz, Deborah organization: Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Germany – sequence: 3 givenname: Lianne surname: Schmaal fullname: Schmaal, Lianne organization: Department of Psychiatry and Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands – sequence: 4 givenname: Leonardo surname: Tozzi fullname: Tozzi, Leonardo organization: Department of Psychiatry and Psychotherapy, Otto von Guericke University of Magdeburg, Germany – sequence: 5 givenname: Henrik surname: Dobrowolny fullname: Dobrowolny, Henrik organization: Department of Psychiatry and Psychotherapy, Otto von Guericke University of Magdeburg, Germany – sequence: 6 givenname: Dan J. surname: Stein fullname: Stein, Dan J. organization: Department of Psychiatry and Mental Health, University of Cape Town, South Africa – sequence: 7 givenname: Dick J. surname: Veltman fullname: Veltman, Dick J. organization: Department of Psychiatry and Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands – sequence: 8 givenname: Katharina surname: Wittfeld fullname: Wittfeld, Katharina organization: German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, Germany – sequence: 9 givenname: Theo G.M. surname: van Erp fullname: van Erp, Theo G.M. organization: Department of Psychiatry and Human Behavior, University of California, Irvine, CA, USA – sequence: 10 givenname: Neda surname: Jahanshad fullname: Jahanshad, Neda organization: Imaging Genetics Center, Department of Neurology, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA – sequence: 11 givenname: Andrea surname: Block fullname: Block, Andrea organization: Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Germany – sequence: 12 givenname: Katrin surname: Hegenscheid fullname: Hegenscheid, Katrin organization: Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Germany – sequence: 13 givenname: Henry surname: Völzke fullname: Völzke, Henry organization: Institute for Community Medicine, University Medicine Greifswald, Germany – sequence: 14 givenname: Jim surname: Lagopoulos fullname: Lagopoulos, Jim organization: Brain and Mind Centre, University of Sydney, Camperdown, Australia – sequence: 15 givenname: Sean N. surname: Hatton fullname: Hatton, Sean N. organization: Brain and Mind Centre, University of Sydney, Camperdown, Australia – sequence: 16 givenname: Ian B. surname: Hickie fullname: Hickie, Ian B. organization: Brain and Mind Centre, University of Sydney, Camperdown, Australia – sequence: 17 givenname: Eva Maria surname: Frey fullname: Frey, Eva Maria organization: Department of Psychiatry, University of Regensburg, Regensburg, Germany – sequence: 18 givenname: Angela surname: Carballedo fullname: Carballedo, Angela organization: Department of Psychiatry and Psychotherapy, Otto von Guericke University of Magdeburg, Germany – sequence: 19 givenname: Samantha J. surname: Brooks fullname: Brooks, Samantha J. organization: Department of Psychiatry and Mental Health, University of Cape Town, South Africa – sequence: 20 givenname: Daniella surname: Vuletic fullname: Vuletic, Daniella organization: Department of Psychiatry and Mental Health, University of Cape Town, South Africa – sequence: 21 givenname: Anne surname: Uhlmann fullname: Uhlmann, Anne organization: Department of Psychiatry and Mental Health, University of Cape Town, South Africa – sequence: 22 givenname: Ilya M. surname: Veer fullname: Veer, Ilya M. organization: Charité Universitätsmedizin Berlin, Department of Psychiatry and Psychotherapy, Division of Mind and Brain Research, Berlin, Germany – sequence: 23 givenname: Henrik surname: Walter fullname: Walter, Henrik organization: Charité Universitätsmedizin Berlin, Department of Psychiatry and Psychotherapy, Division of Mind and Brain Research, Berlin, Germany – sequence: 24 givenname: Knut surname: Schnell fullname: Schnell, Knut organization: Department of General Psychiatry, University Hospital Heidelberg, Germany – sequence: 25 givenname: Dominik surname: Grotegerd fullname: Grotegerd, Dominik organization: Department of Psychiatry and Psychotherapy, University of Münster, Germany – sequence: 26 givenname: Volker surname: Arolt fullname: Arolt, Volker organization: Department of Psychiatry and Psychotherapy, University of Münster, Germany – sequence: 27 givenname: Harald surname: Kugel fullname: Kugel, Harald organization: Department of Clinical Radiology, University of Münster, Germany – sequence: 28 givenname: Elisabeth surname: Schramm fullname: Schramm, Elisabeth organization: Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Germany – sequence: 29 givenname: Carsten surname: Konrad fullname: Konrad, Carsten organization: Department of Psychiatry and Psychotherapy, Agaplesion Diakoniklinikum, Rotenburg, Germany – sequence: 30 givenname: Bartosz surname: Zurowski fullname: Zurowski, Bartosz organization: Center for Integrative Psychiatry, University of Lübeck, Lübeck, Germany – sequence: 31 givenname: Bernhard T. surname: Baune fullname: Baune, Bernhard T. organization: Discipline of Psychiatry, School of Medicine, University of Adelaide, SA 5005 Adelaide, Australia – sequence: 32 givenname: Nic J.A. surname: van der Wee fullname: van der Wee, Nic J.A. organization: Department of Psychiatry, Leiden Institute for Brain and Cognition and Leiden Center for Translational Neuroscience, Leiden, The Netherlands – sequence: 33 givenname: Marie-Jose surname: van Tol fullname: van Tol, Marie-Jose organization: Department of Neuroscience, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands – sequence: 34 givenname: Brenda W.J.H. surname: Penninx fullname: Penninx, Brenda W.J.H. organization: Department of Psychiatry and Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands – sequence: 35 givenname: Paul M. surname: Thompson fullname: Thompson, Paul M. organization: Imaging Genetics Center, Department of Neurology, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA – sequence: 36 givenname: Derrek P. surname: Hibar fullname: Hibar, Derrek P. organization: Imaging Genetics Center, Department of Neurology, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA – sequence: 37 givenname: Udo surname: Dannlowski fullname: Dannlowski, Udo organization: Department of Psychiatry and Psychotherapy, University of Münster, Germany – sequence: 38 givenname: Hans J. surname: Grabe fullname: Grabe, Hans J. organization: Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Germany |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/27918926$$D View this record in MEDLINE/PubMed |
| BookMark | eNqVkkuP0zAUhS00iOkM_AWUJZsGPxLH2SCgGh7SSEg81pYft9QhtYPtVOq_x1GHDiyQhpWl6-PvHt9zr9CFDx4QqgiuCSb85VAPUzqanYuQaloqNSE1JvgRWhHR9WvCuv4CrTCmdM36ll-iq5QGjHFHSfMEXdKuJ6KnfIU-b3ZutLsQbKXsAWJy-Vi5_aRMTlXwlY7K-SrN2oSYnVFjlXKcTZ5L5yrCCAflc5VDZWEqpeSCf4oeb9WY4NndeY2-vbv5uvmwvv30_uPmze3a8LbL60YzoJpiwYymvbVN2wutjdo2vG0arW1jQeum6wRTIAzgfttRUIJxYxlVlF2jVyfuNOs9WAM-RzXKKbq9ikcZlJN_33i3k9_DQbYtb1pCCuDFHSCGnzOkLPcuGRhH5SHMSRLRcFa8iq5In__Z69zk9yCLQJwEJoaUImzPEoLlkpkc5H1mcslMEiJLZvf_OD81LqtcJllcu_EhgLcnAJRpHxxEmYwDb8AWqcnSBvcfLs4QMzq_JP4DjpCGMEdf0pREJiqx_LLs1rJahDPMOW8L4PW_AQ_z8At6WejP |
| CitedBy_id | crossref_primary_10_1017_S0033291722001623 crossref_primary_10_1016_j_ynstr_2024_100643 crossref_primary_10_1016_j_pharep_2018_10_004 crossref_primary_10_1186_s12888_025_06485_0 crossref_primary_10_7554_eLife_58301 crossref_primary_10_1038_s41398_021_01352_4 crossref_primary_10_1080_20008066_2024_2358681 crossref_primary_10_3389_fpsyt_2021_744690 crossref_primary_10_1016_j_jad_2019_04_054 crossref_primary_10_1038_s41467_022_32617_1 crossref_primary_10_1016_j_neubiorev_2021_01_025 crossref_primary_10_1016_j_chiabu_2024_107100 crossref_primary_10_1007_s11682_021_00450_7 crossref_primary_10_1016_j_pscychresns_2022_111533 crossref_primary_10_1371_journal_pone_0233670 crossref_primary_10_1038_s41380_023_02295_6 crossref_primary_10_1111_desc_12775 crossref_primary_10_1016_j_jpsychires_2024_12_032 crossref_primary_10_1093_geroni_igz016 crossref_primary_10_1016_j_jpsychires_2017_03_019 crossref_primary_10_3389_fpsyt_2018_00329 crossref_primary_10_1192_j_eurpsy_2022_2347 crossref_primary_10_1016_j_jpsychires_2024_02_014 crossref_primary_10_1017_S0033291721005304 crossref_primary_10_3389_fpsyt_2021_658205 crossref_primary_10_1016_j_cont_2022_100570 crossref_primary_10_1111_cns_13048 crossref_primary_10_1016_S2215_0366_19_30044_6 crossref_primary_10_1080_09297049_2023_2185216 crossref_primary_10_1016_j_pscychresns_2019_04_012 crossref_primary_10_1016_j_schres_2019_01_048 crossref_primary_10_1038_npp_2017_83 crossref_primary_10_1038_s41380_019_0627_6 crossref_primary_10_1038_s41598_021_93242_4 crossref_primary_10_1016_j_psyneuen_2018_09_027 crossref_primary_10_1016_j_neulet_2021_136301 crossref_primary_10_3389_fcell_2020_00867 crossref_primary_10_1017_S0033291721002087 crossref_primary_10_1080_87565641_2018_1522538 crossref_primary_10_1016_j_bpsc_2019_12_008 crossref_primary_10_1016_j_comppsych_2023_152368 crossref_primary_10_1016_j_biopsych_2022_06_007 crossref_primary_10_1002_hbm_25292 crossref_primary_10_3389_fnbeh_2023_927389 crossref_primary_10_1038_s41386_019_0472_y crossref_primary_10_1016_j_psychres_2018_10_071 crossref_primary_10_1038_s41380_022_01687_4 crossref_primary_10_1016_j_medp_2024_100038 crossref_primary_10_1016_j_nicl_2022_103180 crossref_primary_10_1162_imag_a_00145 crossref_primary_10_1016_j_bja_2023_03_008 crossref_primary_10_1038_s41398_020_0705_1 crossref_primary_10_3389_fpsyt_2019_00494 crossref_primary_10_1016_j_yfrne_2019_100796 crossref_primary_10_1016_j_jad_2024_09_020 crossref_primary_10_1038_s41398_020_0842_6 crossref_primary_10_1007_s11682_023_00772_8 crossref_primary_10_3389_fpubh_2020_536188 crossref_primary_10_1016_j_bpsc_2024_07_002 crossref_primary_10_1016_j_chiabu_2020_104361 crossref_primary_10_1155_2017_5282670 crossref_primary_10_1111_pcn_13337 crossref_primary_10_1186_s12888_024_06306_w crossref_primary_10_1038_s41398_022_02153_z crossref_primary_10_1002_jnr_24835 crossref_primary_10_3389_fnhum_2018_00007 crossref_primary_10_1007_s12264_021_00638_3 crossref_primary_10_1016_S2589_7500_23_00250_9 crossref_primary_10_1002_hbm_25438 crossref_primary_10_1017_S003329171900093X crossref_primary_10_1002_hbm_24988 |
| Cites_doi | 10.1017/S0033291715001415 10.1207/s15327906mbr1503_7 10.1126/science.1083328 10.1001/archpsyc.65.10.1156 10.1176/appi.ajp.161.11.1957 10.1017/S0954579415000139 10.31887/DCNS.2007.9.2/rbonelli 10.1007/s00127-016-1198-3 10.1016/S0006-3223(96)00162-X 10.1016/S0896-6273(02)00569-X 10.1017/S0033291715000574 10.1002/hipo.10212 10.1002/neu.1079 10.1176/ajp.151.8.1132 10.1523/JNEUROSCI.10-12-04035.1990 10.1111/j.1600-0447.2010.01644.x 10.1038/npp.2015.344 10.1089/104454603321666207 10.1523/JNEUROSCI.16-10-03534.1996 10.1016/S0006-3223(03)00634-6 10.1176/appi.ajp.2013.12070957 10.1176/appi.ajp.161.4.598 10.1016/j.nbd.2012.03.012 10.1016/j.biopsych.2015.05.017 10.1016/S0145-2134(02)00541-0 10.1001/archgenpsychiatry.2011.60 10.1001/archpediatrics.2011.565 10.1002/hbm.23108 10.1016/j.biopsych.2010.06.011 10.1038/npp.2010.8 10.1016/j.biopsych.2011.10.021 10.1016/S0924-9338(02)00654-5 10.1016/j.biopsych.2005.12.016 10.1146/annurev.ne.09.030186.002041 10.1016/j.jad.2013.06.037 |
| ContentType | Journal Article |
| Copyright | 2016 Copyright © 2016. Published by Elsevier Ltd. |
| Copyright_xml | – notice: 2016 – notice: Copyright © 2016. Published by Elsevier Ltd. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 5PM |
| DOI | 10.1016/j.jpsychires.2016.11.010 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1879-1379 |
| EndPage | 65 |
| ExternalDocumentID | PMC5564511 27918926 10_1016_j_jpsychires_2016_11_010 S0022395616306665 1_s2_0_S0022395616306665 |
| Genre | Multicenter Study Journal Article |
| GrantInformation_xml | – fundername: NICHD NIH HHS grantid: R01 HD050735 – fundername: NIBIB NIH HHS grantid: U54 EB020403 – fundername: NIDA NIH HHS grantid: R00 DA023549 |
| GroupedDBID | --- --K --M .1- .FO .GJ .~1 0R~ 1B1 1P~ 1RT 1~. 1~5 29L 4.4 457 4G. 53G 5GY 5RE 5VS 7-5 71M 8P~ 9JM 9JO AABNK AADFP AAEDT AAEDW AAGJA AAGUQ AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AATTM AAXKI AAXLA AAXUO AAYWO ABBQC ABCQJ ABFNM ABIVO ABJNI ABLJU ABMAC ABMZM ABOYX ABPPZ ABWVN ABXDB ACDAQ ACGFS ACHQT ACIEU ACIUM ACNCT ACRLP ACRPL ACVFH ACXNI ADBBV ADCNI ADEZE ADMUD ADNMO ADXHL AEBSH AEIPS AEKER AENEX AEUPX AEVXI AFJKZ AFPUW AFRHN AFTJW AFXIZ AGCQF AGHFR AGQPQ AGUBO AGWIK AGYEJ AHHHB AIEXJ AIGII AIIUN AIKHN AITUG AJRQY AJUYK AKBMS AKRWK AKYEP ALMA_UNASSIGNED_HOLDINGS AMRAJ ANKPU ANZVX APXCP ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC BNPGV CS3 DU5 EBS EFJIC EFKBS EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HEG HF~ HMK HMO HMQ HMW HVGLF HZ~ IHE J1W K-O KOM L7B M29 M2V M39 M3V M41 MO0 MOBAO N9A O-L O9- OAUVE OH0 OKEIE OU- OZT P-8 P-9 P2P PC. Q38 R2- ROL RPZ SAE SCC SDF SDG SDP SEL SES SEW SNS SPCBC SPS SSB SSH SSN SSY SSZ T5K WUQ YQT Z5R ZGI ~G- AACTN AFCTW AFKWA AJOXV AMFUW PKN RIG AADPK AAIAV ABLVK ABYKQ AFYLN AJBFU EFLBG LCYCR ZA5 AAYXX AGRNS CITATION CGR CUY CVF ECM EIF NPM 7X8 ACLOT ~HD 5PM |
| ID | FETCH-LOGICAL-c657t-4b3e2b2083cb29dd4598bbcaf46544bbd4debb47783ae8ce09f72ea836cd32a23 |
| IEDL.DBID | .~1 |
| ISSN | 0022-3956 |
| IngestDate | Thu Aug 21 14:11:21 EDT 2025 Sun Sep 28 08:26:30 EDT 2025 Mon Jul 21 05:36:20 EDT 2025 Tue Jul 01 01:03:51 EDT 2025 Thu Apr 24 23:03:27 EDT 2025 Fri Feb 23 02:28:07 EST 2024 Tue Feb 25 19:54:02 EST 2025 Tue Aug 26 20:36:10 EDT 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Keywords | Childhood adversity ENIGMA Depression Caudate MRI Hippocampus |
| Language | English |
| License | Copyright © 2016. Published by Elsevier Ltd. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c657t-4b3e2b2083cb29dd4598bbcaf46544bbd4debb47783ae8ce09f72ea836cd32a23 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Both authors contributed equally. |
| OpenAccessLink | http://hdl.handle.net/1887/116468 |
| PMID | 27918926 |
| PQID | 1846365787 |
| PQPubID | 23479 |
| PageCount | 8 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_5564511 proquest_miscellaneous_1846365787 pubmed_primary_27918926 crossref_primary_10_1016_j_jpsychires_2016_11_010 crossref_citationtrail_10_1016_j_jpsychires_2016_11_010 elsevier_sciencedirect_doi_10_1016_j_jpsychires_2016_11_010 elsevier_clinicalkeyesjournals_1_s2_0_S0022395616306665 elsevier_clinicalkey_doi_10_1016_j_jpsychires_2016_11_010 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2017-03-01 |
| PublicationDateYYYYMMDD | 2017-03-01 |
| PublicationDate_xml | – month: 03 year: 2017 text: 2017-03-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England |
| PublicationTitle | Journal of psychiatric research |
| PublicationTitleAlternate | J Psychiatr Res |
| PublicationYear | 2017 |
| Publisher | Elsevier Ltd |
| Publisher_xml | – name: Elsevier Ltd |
| References | Curran, Adamson, Stringer, Rosato, Leavey (bib11) 2016; 51 Teicher, Samson (bib32) 2013; 170 Fischl, Salat, Busa, Albert, Dieterich, Haselgrove, van der Kouwe, Killiany, Kennedy, Klaveness, Montillo, Makris, Rosen, Dale (bib16) 2002; 33 Dannlowski, Stuhrmann, Beutelmann, Zwanzger, Lenzen, Grotegerd, Domschke, Hohoff, Ohrmann, Bauer, Lindner, Postert, Konrad, Arolt, Heindel, Suslow, Kugel (bib12) 2012; 71 Frodl, Koutsouleris, Bottlender, Born, Jäger, Scupin, Reiser, Möller, Meisenzahl (bib20) 2008; 65 Campbell, Marriott, Nahmias, MacQueen (bib8) 2004; 161 Steiger (bib31) 1980; 15 Bernstein, Fink, Handelsman, Foote, Lovejoy, Wenzel, Sapareto, Ruggiero (bib4) 1994; 151 Vermetten, Vythilingam, Southwick, Charney, Bremner (bib36) 2003; 54 Frodl, Reinhold, Koutsouleris, Donohoe, Bondy, Reiser, Moller, Meisenzahl (bib19) 2010; 35 Nusslock, Miller (bib27) 2016; 80 Cowell, Cicchetti, Rogosch, Toth (bib10) 2015; 27 Everaerd, Klumpers, Zwiers, Guadalupe, Franke, van Oostrom, Schene, Fernandez, Tendolkar (bib15) 2016; 41 Magarinos, McEwen, Flugge, Fuchs (bib25) 1996; 16 Videbech, Ravnkilde (bib37) 2004; 161 Trotta, Murray, Fisher (bib33) 2015; 45 McKinnon, Yucel, Nazarov, MacQueen (bib26) 2009; 34 Schmaal, Veltman, van Erp, Samann, Frodl, Jahanshad, Loehrer, Tiemeier, Hofman, Niessen, Vernooij, Ikram, Wittfeld, Grabe, Block, Hegenscheid, Volzke, Hoehn, Czisch, Lagopoulos, Hatton, Hickie, Goya-Maldonado, Kramer, Gruber, Couvy-Duchesne, Renteria, Strike, Mills, de Zubicaray, McMahon, Medland, Martin, Gillespie, Wright, Hall, MacQueen, Frey, Carballedo, van Velzen, van Tol, van der Wee, Veer, Walter, Schnell, Schramm, Normann, Schoepf, Konrad, Zurowski, Nickson, McIntosh, Papmeyer, Whalley, Sussmann, Godlewska, Cowen, Fischer, Rose, Penninx, Thompson, Hibar (bib30) 2015 Edmiston, Wang, Mazure, Guiney, Sinha, Mayes, Blumberg (bib14) 2011; 165 van Harmelen, van Tol, van der Wee, Veltman, Aleman, Spinhoven, van Buchem, Zitman, Penninx, Elzinga (bib35) 2010; 68 Kempton, Salvador, Munafo, Geddes, Simmons, Frangou, Williams (bib22) 2011; 68 Wellman (bib38) 2001; 49 Duman (bib13) 2002; 17 Gerritsen, van Velzen, Schmaal, van der Graaf, van der Wee, van Tol, Penninx, Geerlings (bib21) 2015; 45 Frodl, Jager, Smajstrlova, Born, Bottlender, Palladino, Reiser, Moller, Meisenzahl (bib17) 2008; 33 MacMillan, Szeszko, Moore, Madden, Lorch, Ivey, Banerjee, Rosenberg (bib24) 2003; 13 Ahdidan, Hviid, Chakravarty, Ravnkilde, Rosenberg, Rodell, Stodkilde-Jorgensen, Videbech (bib1) 2011; 123 Bernstein, Stein, Newcomb, Walker, Pogge, Ahluvalia, Stokes, Handelsman, Medrano, Desmond, Zule (bib5) 2003; 27 Cohen, Grieve, Hoth, Paul, Sweet, Tate, Gunstad, Stroud, McCaffery, Hitsman, Niaura, Clark, McFarlane, Bryant, Gordon, Williams (bib9) 2006; 59 Bonelli, Cummings (bib6) 2007; 9 Frodl, O'Keane (bib18) 2013; 52 Pagliaccio, Barch (bib28) 2015 Tunnard, Rane, Wooderson, Markopoulou, Poon, Fekadu, Juruena, Cleare (bib34) 2014; 152–154 Alexander, DeLong, Strick (bib2) 1986; 9 Woolley, Gould, Frankfurt, McEwen (bib39) 1990; 10 Kole, Czeh, Fuchs (bib23) 2004; 14 Santarelli, Saxe, Gross, Surget, Battaglia, Dulawa, Weisstaub, Lee, Duman, Arancio, Belzung, Hen (bib29) 2003; 301 Bremner, Randall, Vermetten, Staib, Bronen, Mazure, Capelli, McCarthy, Innis, Charney (bib7) 1997; 41 Arnone, Job, Selvaraj, Abe, Amico, Cheng, Colloby, O'Brien, Frodl, Gotlib, Ham, Kim, Koolschijn, Perico, Salvadore, Thomas, Van Tol, van der Wee, Veltman, Wagner, McIntosh (bib3) 2016; 37 Schmaal (10.1016/j.jpsychires.2016.11.010_bib30) 2015 Cowell (10.1016/j.jpsychires.2016.11.010_bib10) 2015; 27 Frodl (10.1016/j.jpsychires.2016.11.010_bib17) 2008; 33 Steiger (10.1016/j.jpsychires.2016.11.010_bib31) 1980; 15 Bernstein (10.1016/j.jpsychires.2016.11.010_bib5) 2003; 27 Pagliaccio (10.1016/j.jpsychires.2016.11.010_bib28) 2015 Fischl (10.1016/j.jpsychires.2016.11.010_bib16) 2002; 33 Frodl (10.1016/j.jpsychires.2016.11.010_bib18) 2013; 52 Tunnard (10.1016/j.jpsychires.2016.11.010_bib34) 2014; 152–154 Edmiston (10.1016/j.jpsychires.2016.11.010_bib14) 2011; 165 Vermetten (10.1016/j.jpsychires.2016.11.010_bib36) 2003; 54 Gerritsen (10.1016/j.jpsychires.2016.11.010_bib21) 2015; 45 van Harmelen (10.1016/j.jpsychires.2016.11.010_bib35) 2010; 68 Frodl (10.1016/j.jpsychires.2016.11.010_bib19) 2010; 35 Kole (10.1016/j.jpsychires.2016.11.010_bib23) 2004; 14 Woolley (10.1016/j.jpsychires.2016.11.010_bib39) 1990; 10 Trotta (10.1016/j.jpsychires.2016.11.010_bib33) 2015; 45 Kempton (10.1016/j.jpsychires.2016.11.010_bib22) 2011; 68 Bernstein (10.1016/j.jpsychires.2016.11.010_bib4) 1994; 151 Bremner (10.1016/j.jpsychires.2016.11.010_bib7) 1997; 41 Frodl (10.1016/j.jpsychires.2016.11.010_bib20) 2008; 65 Wellman (10.1016/j.jpsychires.2016.11.010_bib38) 2001; 49 Campbell (10.1016/j.jpsychires.2016.11.010_bib8) 2004; 161 Santarelli (10.1016/j.jpsychires.2016.11.010_bib29) 2003; 301 Nusslock (10.1016/j.jpsychires.2016.11.010_bib27) 2016; 80 Dannlowski (10.1016/j.jpsychires.2016.11.010_bib12) 2012; 71 Arnone (10.1016/j.jpsychires.2016.11.010_bib3) 2016; 37 Cohen (10.1016/j.jpsychires.2016.11.010_bib9) 2006; 59 Alexander (10.1016/j.jpsychires.2016.11.010_bib2) 1986; 9 Bonelli (10.1016/j.jpsychires.2016.11.010_bib6) 2007; 9 Curran (10.1016/j.jpsychires.2016.11.010_bib11) 2016; 51 Duman (10.1016/j.jpsychires.2016.11.010_bib13) 2002; 17 Magarinos (10.1016/j.jpsychires.2016.11.010_bib25) 1996; 16 Videbech (10.1016/j.jpsychires.2016.11.010_bib37) 2004; 161 McKinnon (10.1016/j.jpsychires.2016.11.010_bib26) 2009; 34 Teicher (10.1016/j.jpsychires.2016.11.010_bib32) 2013; 170 MacMillan (10.1016/j.jpsychires.2016.11.010_bib24) 2003; 13 Ahdidan (10.1016/j.jpsychires.2016.11.010_bib1) 2011; 123 Everaerd (10.1016/j.jpsychires.2016.11.010_bib15) 2016; 41 21219263 - Acta Psychiatr Scand. 2011 Mar;123(3):211-9 26122586 - Mol Psychiatry. 2016 Jun;21(6):806-12 17726913 - Dialogues Clin Neurosci. 2007;9(2):141-51 20147891 - Neuropsychopharmacology. 2010 May;35(6):1383-90 2269895 - J Neurosci. 1990 Dec;10(12):4035-9 25903153 - Psychol Med. 2015;45(12):2481-98 14512209 - Biol Psychiatry. 2003 Oct 1;54(7):693-702 19125212 - J Psychiatry Neurosci. 2009 Jan;34(1):41-54 26576924 - Neuropsychopharmacology. 2016 Jun;41(7):1716-23 12907793 - Science. 2003 Aug 8;301(5634):805-9 26794186 - Multivariate Behav Res. 1980 Jul 1;15(3):335-52 11745662 - J Neurobiol. 2001 Nov 15;49(3):245-53 12804127 - J Child Adolesc Psychopharmacol. 2003 Spring;13(1):65-73 22112927 - Biol Psychiatry. 2012 Feb 15;71(4):286-93 26204801 - Psychol Med. 2015 Dec;45(16):3517-26 26854015 - Hum Brain Mapp. 2016 Apr;37(4):1393-404 8627386 - J Neurosci. 1996 May 15;16(10):3534-40 18838632 - Arch Gen Psychiatry. 2008 Oct;65(10):1156-65 11832223 - Neuron. 2002 Jan 31;33(3):341-55 23880448 - J Affect Disord. 2014 Jan;152-154:122-30 20692648 - Biol Psychiatry. 2010 Nov 1;68(9):832-8 12615092 - Child Abuse Negl. 2003 Feb;27(2):169-90 3085570 - Annu Rev Neurosci. 1986;9:357-81 15177086 - Eur Psychiatry. 2002 Jul;17 Suppl 3:306-10 22426398 - Neurobiol Dis. 2013 Apr;52:24-37 21727252 - Arch Gen Psychiatry. 2011 Jul;68(7):675-90 23982148 - Am J Psychiatry. 2013 Oct;170(10):1114-33 26166230 - Biol Psychiatry. 2016 Jul 1;80(1):23-32 18787661 - J Psychiatry Neurosci. 2008 Sep;33(5):423-30 15056502 - Am J Psychiatry. 2004 Apr;161(4):598-607 26952327 - Soc Psychiatry Psychiatr Epidemiol. 2016 May;51(5):647-57 16616722 - Biol Psychiatry. 2006 May 15;59(10):975-82 8988792 - Biol Psychiatry. 1997 Jan 1;41(1):23-32 15514393 - Am J Psychiatry. 2004 Nov;161(11):1957-66 8037246 - Am J Psychiatry. 1994 Aug;151(8):1132-6 15318332 - Hippocampus. 2004;14(6):742-51 25997769 - Dev Psychopathol. 2015 May;27(2):521-33 22147775 - Arch Pediatr Adolesc Med. 2011 Dec;165(12):1069-77 |
| References_xml | – volume: 161 start-page: 598 year: 2004 end-page: 607 ident: bib8 article-title: Lower hippocampal volume in patients suffering from depression: a meta-analysis publication-title: Am. J. Psychiatry – year: 2015 ident: bib28 article-title: Early Life Adversity and Risk for Depression: Alterations in Cortisol and Brain Structure and Function as Mediating Mechanisms – volume: 59 start-page: 975 year: 2006 end-page: 982 ident: bib9 article-title: Early life stress and morphometry of the adult anterior cingulate cortex and caudate nuclei publication-title: Biol. Psychiatry – volume: 45 start-page: 3517 year: 2015 end-page: 3526 ident: bib21 article-title: Childhood maltreatment modifies the relationship of depression with hippocampal volume publication-title: Psychol. Med. – volume: 15 start-page: 335 year: 1980 end-page: 352 ident: bib31 article-title: Testing pattern hypotheses on correlation matrices: alternative Statistics and some empirical results publication-title: Multivar. Behav. Res. – volume: 54 start-page: 693 year: 2003 end-page: 702 ident: bib36 article-title: Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder publication-title: Biol. Psychiatry – volume: 33 start-page: 341 year: 2002 end-page: 355 ident: bib16 article-title: Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain publication-title: Neuron – volume: 35 start-page: 1383 year: 2010 end-page: 1390 ident: bib19 article-title: Childhood stress, serotonin transporter gene and brain structures in major depression publication-title: Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol. – volume: 68 start-page: 675 year: 2011 end-page: 690 ident: bib22 article-title: Structural neuroimaging studies in major depressive disorder. Meta-analysis and comparison with bipolar disorder publication-title: Arch. Gen. Psychiatry – volume: 80 start-page: 23 year: 2016 end-page: 32 ident: bib27 article-title: Early-life adversity and physical and emotional health across the lifespan: a neuroimmune network hypothesis publication-title: Biol. Psychiatry – volume: 165 start-page: 1069 year: 2011 end-page: 1077 ident: bib14 article-title: Corticostriatal-limbic gray matter morphology in adolescents with self-reported exposure to childhood maltreatment publication-title: Arch. Pediatr. Adolesc. Med. – volume: 16 start-page: 3534 year: 1996 end-page: 3540 ident: bib25 article-title: Chronic psychosocial stress causes apical dendritic atrophy of hippocampal CA3 pyramidal neurons in subordinate tree shrews publication-title: J. Neurosci. – volume: 68 start-page: 832 year: 2010 end-page: 838 ident: bib35 article-title: Reduced medial prefrontal cortex volume in adults reporting childhood emotional maltreatment publication-title: Biol. Psychiatry – volume: 65 start-page: 1156 year: 2008 end-page: 1165 ident: bib20 article-title: Depression-related variation in brain morphology over 3 years: effects of stress? publication-title: Archives General Psychiatry – volume: 41 start-page: 23 year: 1997 end-page: 32 ident: bib7 article-title: Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse–a preliminary report publication-title: Biol. Psychiatry – volume: 161 start-page: 1957 year: 2004 end-page: 1966 ident: bib37 article-title: Hippocampal volume and depression: a meta-analysis of MRI studies publication-title: Am. J. Psychiatry – volume: 37 start-page: 1393 year: 2016 end-page: 1404 ident: bib3 article-title: Computational meta-analysis of statistical parametric maps in major depression publication-title: Hum. Brain Mapp. – volume: 17 start-page: 306 year: 2002 end-page: 310 ident: bib13 article-title: Pathophysiology of depression: the concept of synaptic plasticity publication-title: Eur. Psychiatry – volume: 13 start-page: 65 year: 2003 end-page: 73 ident: bib24 article-title: Increased amygdala: hippocampal volume ratios associated with severity of anxiety in pediatric major depression publication-title: J. Child. Adolesc. Psychopharmacol. – volume: 49 start-page: 245 year: 2001 end-page: 253 ident: bib38 article-title: Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration publication-title: J. Neurobiol. – volume: 9 start-page: 141 year: 2007 end-page: 151 ident: bib6 article-title: Frontal-subcortical circuitry and behavior publication-title: Dialogues Clin. Neurosci. – volume: 14 start-page: 742 year: 2004 end-page: 751 ident: bib23 article-title: Homeostatic maintenance in excitability of tree shrew hippocampal CA3 pyramidal neurons after chronic stress publication-title: Hippocampus – volume: 71 start-page: 286 year: 2012 end-page: 293 ident: bib12 article-title: Limbic scars: long-term consequences of childhood maltreatment revealed by functional and structural magnetic resonance imaging publication-title: Biol. Psychiatry – volume: 10 start-page: 4035 year: 1990 end-page: 4039 ident: bib39 article-title: Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons publication-title: J. Neurosci. – volume: 41 start-page: 1716 year: 2016 end-page: 1723 ident: bib15 article-title: Childhood abuse and deprivation are associated with distinct sex-dependent differences in brain morphology publication-title: Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol. – volume: 301 start-page: 805 year: 2003 end-page: 809 ident: bib29 article-title: Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants publication-title: Science – volume: 170 start-page: 1114 year: 2013 end-page: 1133 ident: bib32 article-title: Childhood maltreatment and psychopathology: a case for ecophenotypic variants as clinically and neurobiologically distinct subtypes publication-title: Am. J. Psychiatry – volume: 27 start-page: 169 year: 2003 end-page: 190 ident: bib5 article-title: Development and validation of a brief screening version of the Childhood Trauma Questionnaire publication-title: Child. Abuse Negl. – volume: 152–154 start-page: 122 year: 2014 end-page: 130 ident: bib34 article-title: The impact of childhood adversity on suicidality and clinical course in treatment-resistant depression publication-title: J. Affect. Disord. – volume: 27 start-page: 521 year: 2015 end-page: 533 ident: bib10 article-title: Childhood maltreatment and its effect on neurocognitive functioning: timing and chronicity matter publication-title: Dev. Psychopathol. – volume: 52 start-page: 24 year: 2013 end-page: 37 ident: bib18 article-title: How does the brain deal with cumulative stress? A review with focus on developmental stress, HPA axis function and hippocampal structure in humans publication-title: Neurobiol. Dis. – volume: 123 start-page: 211 year: 2011 end-page: 219 ident: bib1 article-title: Longitudinal MR study of brain structure and hippocampus volume in major depressive disorder publication-title: Acta Psychiatr. Scand. – volume: 45 start-page: 2481 year: 2015 end-page: 2498 ident: bib33 article-title: The impact of childhood adversity on the persistence of psychotic symptoms: a systematic review and meta-analysis publication-title: Psychol. Med. – volume: 151 start-page: 1132 year: 1994 end-page: 1136 ident: bib4 article-title: Initial reliability and validity of a new retrospective measure of child abuse and neglect publication-title: Am. J. Psychiatry – year: 2015 ident: bib30 article-title: Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group publication-title: Mol Psychiatry – volume: 33 start-page: 423 year: 2008 end-page: 430 ident: bib17 article-title: Effect of hippocampal and amygdala volumes on clinical outcomes in major depression: a 3-year prospective magnetic resonance imaging study publication-title: J. Psychiatry Neurosci. – volume: 9 start-page: 357 year: 1986 end-page: 381 ident: bib2 article-title: Parallel organization of functionally segregated circuits linking basal ganglia and cortex publication-title: Annu. Rev. Neurosci. – volume: 51 start-page: 647 year: 2016 end-page: 657 ident: bib11 article-title: Severity of mental illness as a result of multiple childhood adversities: US National Epidemiologic Survey publication-title: Soc. Psychiatry Psychiatric Epidemiol. – volume: 34 start-page: 41 year: 2009 end-page: 54 ident: bib26 article-title: A meta-analysis examining clinical predictors of hippocampal volume in patients with major depressive disorder publication-title: J. Psychiatry Neurosci. – volume: 45 start-page: 3517 issue: 16 year: 2015 ident: 10.1016/j.jpsychires.2016.11.010_bib21 article-title: Childhood maltreatment modifies the relationship of depression with hippocampal volume publication-title: Psychol. Med. doi: 10.1017/S0033291715001415 – volume: 15 start-page: 335 issue: 3 year: 1980 ident: 10.1016/j.jpsychires.2016.11.010_bib31 article-title: Testing pattern hypotheses on correlation matrices: alternative Statistics and some empirical results publication-title: Multivar. Behav. Res. doi: 10.1207/s15327906mbr1503_7 – volume: 301 start-page: 805 issue: 5634 year: 2003 ident: 10.1016/j.jpsychires.2016.11.010_bib29 article-title: Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants publication-title: Science doi: 10.1126/science.1083328 – volume: 65 start-page: 1156 issue: 10 year: 2008 ident: 10.1016/j.jpsychires.2016.11.010_bib20 article-title: Depression-related variation in brain morphology over 3 years: effects of stress? publication-title: Archives General Psychiatry doi: 10.1001/archpsyc.65.10.1156 – volume: 161 start-page: 1957 issue: 11 year: 2004 ident: 10.1016/j.jpsychires.2016.11.010_bib37 article-title: Hippocampal volume and depression: a meta-analysis of MRI studies publication-title: Am. J. Psychiatry doi: 10.1176/appi.ajp.161.11.1957 – volume: 27 start-page: 521 issue: 2 year: 2015 ident: 10.1016/j.jpsychires.2016.11.010_bib10 article-title: Childhood maltreatment and its effect on neurocognitive functioning: timing and chronicity matter publication-title: Dev. Psychopathol. doi: 10.1017/S0954579415000139 – volume: 9 start-page: 141 issue: 2 year: 2007 ident: 10.1016/j.jpsychires.2016.11.010_bib6 article-title: Frontal-subcortical circuitry and behavior publication-title: Dialogues Clin. Neurosci. doi: 10.31887/DCNS.2007.9.2/rbonelli – volume: 51 start-page: 647 issue: 5 year: 2016 ident: 10.1016/j.jpsychires.2016.11.010_bib11 article-title: Severity of mental illness as a result of multiple childhood adversities: US National Epidemiologic Survey publication-title: Soc. Psychiatry Psychiatric Epidemiol. doi: 10.1007/s00127-016-1198-3 – volume: 34 start-page: 41 issue: 1 year: 2009 ident: 10.1016/j.jpsychires.2016.11.010_bib26 article-title: A meta-analysis examining clinical predictors of hippocampal volume in patients with major depressive disorder publication-title: J. Psychiatry Neurosci. – volume: 41 start-page: 23 issue: 1 year: 1997 ident: 10.1016/j.jpsychires.2016.11.010_bib7 article-title: Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse–a preliminary report publication-title: Biol. Psychiatry doi: 10.1016/S0006-3223(96)00162-X – volume: 33 start-page: 341 issue: 3 year: 2002 ident: 10.1016/j.jpsychires.2016.11.010_bib16 article-title: Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain publication-title: Neuron doi: 10.1016/S0896-6273(02)00569-X – year: 2015 ident: 10.1016/j.jpsychires.2016.11.010_bib30 article-title: Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group publication-title: Mol Psychiatry – volume: 45 start-page: 2481 issue: 12 year: 2015 ident: 10.1016/j.jpsychires.2016.11.010_bib33 article-title: The impact of childhood adversity on the persistence of psychotic symptoms: a systematic review and meta-analysis publication-title: Psychol. Med. doi: 10.1017/S0033291715000574 – volume: 14 start-page: 742 issue: 6 year: 2004 ident: 10.1016/j.jpsychires.2016.11.010_bib23 article-title: Homeostatic maintenance in excitability of tree shrew hippocampal CA3 pyramidal neurons after chronic stress publication-title: Hippocampus doi: 10.1002/hipo.10212 – volume: 49 start-page: 245 issue: 3 year: 2001 ident: 10.1016/j.jpsychires.2016.11.010_bib38 article-title: Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration publication-title: J. Neurobiol. doi: 10.1002/neu.1079 – volume: 151 start-page: 1132 issue: 8 year: 1994 ident: 10.1016/j.jpsychires.2016.11.010_bib4 article-title: Initial reliability and validity of a new retrospective measure of child abuse and neglect publication-title: Am. J. Psychiatry doi: 10.1176/ajp.151.8.1132 – volume: 10 start-page: 4035 issue: 12 year: 1990 ident: 10.1016/j.jpsychires.2016.11.010_bib39 article-title: Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.10-12-04035.1990 – volume: 123 start-page: 211 issue: 3 year: 2011 ident: 10.1016/j.jpsychires.2016.11.010_bib1 article-title: Longitudinal MR study of brain structure and hippocampus volume in major depressive disorder publication-title: Acta Psychiatr. Scand. doi: 10.1111/j.1600-0447.2010.01644.x – volume: 41 start-page: 1716 issue: 7 year: 2016 ident: 10.1016/j.jpsychires.2016.11.010_bib15 article-title: Childhood abuse and deprivation are associated with distinct sex-dependent differences in brain morphology publication-title: Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol. doi: 10.1038/npp.2015.344 – volume: 13 start-page: 65 issue: 1 year: 2003 ident: 10.1016/j.jpsychires.2016.11.010_bib24 article-title: Increased amygdala: hippocampal volume ratios associated with severity of anxiety in pediatric major depression publication-title: J. Child. Adolesc. Psychopharmacol. doi: 10.1089/104454603321666207 – volume: 16 start-page: 3534 issue: 10 year: 1996 ident: 10.1016/j.jpsychires.2016.11.010_bib25 article-title: Chronic psychosocial stress causes apical dendritic atrophy of hippocampal CA3 pyramidal neurons in subordinate tree shrews publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.16-10-03534.1996 – volume: 54 start-page: 693 issue: 7 year: 2003 ident: 10.1016/j.jpsychires.2016.11.010_bib36 article-title: Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder publication-title: Biol. Psychiatry doi: 10.1016/S0006-3223(03)00634-6 – volume: 170 start-page: 1114 issue: 10 year: 2013 ident: 10.1016/j.jpsychires.2016.11.010_bib32 article-title: Childhood maltreatment and psychopathology: a case for ecophenotypic variants as clinically and neurobiologically distinct subtypes publication-title: Am. J. Psychiatry doi: 10.1176/appi.ajp.2013.12070957 – volume: 161 start-page: 598 issue: 4 year: 2004 ident: 10.1016/j.jpsychires.2016.11.010_bib8 article-title: Lower hippocampal volume in patients suffering from depression: a meta-analysis publication-title: Am. J. Psychiatry doi: 10.1176/appi.ajp.161.4.598 – volume: 52 start-page: 24 year: 2013 ident: 10.1016/j.jpsychires.2016.11.010_bib18 article-title: How does the brain deal with cumulative stress? A review with focus on developmental stress, HPA axis function and hippocampal structure in humans publication-title: Neurobiol. Dis. doi: 10.1016/j.nbd.2012.03.012 – volume: 80 start-page: 23 issue: 1 year: 2016 ident: 10.1016/j.jpsychires.2016.11.010_bib27 article-title: Early-life adversity and physical and emotional health across the lifespan: a neuroimmune network hypothesis publication-title: Biol. Psychiatry doi: 10.1016/j.biopsych.2015.05.017 – volume: 27 start-page: 169 issue: 2 year: 2003 ident: 10.1016/j.jpsychires.2016.11.010_bib5 article-title: Development and validation of a brief screening version of the Childhood Trauma Questionnaire publication-title: Child. Abuse Negl. doi: 10.1016/S0145-2134(02)00541-0 – volume: 68 start-page: 675 issue: 7 year: 2011 ident: 10.1016/j.jpsychires.2016.11.010_bib22 article-title: Structural neuroimaging studies in major depressive disorder. Meta-analysis and comparison with bipolar disorder publication-title: Arch. Gen. Psychiatry doi: 10.1001/archgenpsychiatry.2011.60 – volume: 165 start-page: 1069 issue: 12 year: 2011 ident: 10.1016/j.jpsychires.2016.11.010_bib14 article-title: Corticostriatal-limbic gray matter morphology in adolescents with self-reported exposure to childhood maltreatment publication-title: Arch. Pediatr. Adolesc. Med. doi: 10.1001/archpediatrics.2011.565 – year: 2015 ident: 10.1016/j.jpsychires.2016.11.010_bib28 – volume: 37 start-page: 1393 issue: 4 year: 2016 ident: 10.1016/j.jpsychires.2016.11.010_bib3 article-title: Computational meta-analysis of statistical parametric maps in major depression publication-title: Hum. Brain Mapp. doi: 10.1002/hbm.23108 – volume: 68 start-page: 832 issue: 9 year: 2010 ident: 10.1016/j.jpsychires.2016.11.010_bib35 article-title: Reduced medial prefrontal cortex volume in adults reporting childhood emotional maltreatment publication-title: Biol. Psychiatry doi: 10.1016/j.biopsych.2010.06.011 – volume: 35 start-page: 1383 issue: 6 year: 2010 ident: 10.1016/j.jpsychires.2016.11.010_bib19 article-title: Childhood stress, serotonin transporter gene and brain structures in major depression publication-title: Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol. doi: 10.1038/npp.2010.8 – volume: 71 start-page: 286 issue: 4 year: 2012 ident: 10.1016/j.jpsychires.2016.11.010_bib12 article-title: Limbic scars: long-term consequences of childhood maltreatment revealed by functional and structural magnetic resonance imaging publication-title: Biol. Psychiatry doi: 10.1016/j.biopsych.2011.10.021 – volume: 17 start-page: 306 issue: Suppl. 3 year: 2002 ident: 10.1016/j.jpsychires.2016.11.010_bib13 article-title: Pathophysiology of depression: the concept of synaptic plasticity publication-title: Eur. Psychiatry doi: 10.1016/S0924-9338(02)00654-5 – volume: 33 start-page: 423 issue: 5 year: 2008 ident: 10.1016/j.jpsychires.2016.11.010_bib17 article-title: Effect of hippocampal and amygdala volumes on clinical outcomes in major depression: a 3-year prospective magnetic resonance imaging study publication-title: J. Psychiatry Neurosci. – volume: 59 start-page: 975 issue: 10 year: 2006 ident: 10.1016/j.jpsychires.2016.11.010_bib9 article-title: Early life stress and morphometry of the adult anterior cingulate cortex and caudate nuclei publication-title: Biol. Psychiatry doi: 10.1016/j.biopsych.2005.12.016 – volume: 9 start-page: 357 year: 1986 ident: 10.1016/j.jpsychires.2016.11.010_bib2 article-title: Parallel organization of functionally segregated circuits linking basal ganglia and cortex publication-title: Annu. Rev. Neurosci. doi: 10.1146/annurev.ne.09.030186.002041 – volume: 152–154 start-page: 122 year: 2014 ident: 10.1016/j.jpsychires.2016.11.010_bib34 article-title: The impact of childhood adversity on suicidality and clinical course in treatment-resistant depression publication-title: J. Affect. Disord. doi: 10.1016/j.jad.2013.06.037 – reference: 20147891 - Neuropsychopharmacology. 2010 May;35(6):1383-90 – reference: 26576924 - Neuropsychopharmacology. 2016 Jun;41(7):1716-23 – reference: 16616722 - Biol Psychiatry. 2006 May 15;59(10):975-82 – reference: 2269895 - J Neurosci. 1990 Dec;10(12):4035-9 – reference: 8988792 - Biol Psychiatry. 1997 Jan 1;41(1):23-32 – reference: 26952327 - Soc Psychiatry Psychiatr Epidemiol. 2016 May;51(5):647-57 – reference: 18838632 - Arch Gen Psychiatry. 2008 Oct;65(10):1156-65 – reference: 11745662 - J Neurobiol. 2001 Nov 15;49(3):245-53 – reference: 21727252 - Arch Gen Psychiatry. 2011 Jul;68(7):675-90 – reference: 15318332 - Hippocampus. 2004;14(6):742-51 – reference: 8037246 - Am J Psychiatry. 1994 Aug;151(8):1132-6 – reference: 11832223 - Neuron. 2002 Jan 31;33(3):341-55 – reference: 15514393 - Am J Psychiatry. 2004 Nov;161(11):1957-66 – reference: 23982148 - Am J Psychiatry. 2013 Oct;170(10):1114-33 – reference: 25903153 - Psychol Med. 2015;45(12):2481-98 – reference: 22147775 - Arch Pediatr Adolesc Med. 2011 Dec;165(12):1069-77 – reference: 8627386 - J Neurosci. 1996 May 15;16(10):3534-40 – reference: 21219263 - Acta Psychiatr Scand. 2011 Mar;123(3):211-9 – reference: 20692648 - Biol Psychiatry. 2010 Nov 1;68(9):832-8 – reference: 26166230 - Biol Psychiatry. 2016 Jul 1;80(1):23-32 – reference: 17726913 - Dialogues Clin Neurosci. 2007;9(2):141-51 – reference: 26854015 - Hum Brain Mapp. 2016 Apr;37(4):1393-404 – reference: 26122586 - Mol Psychiatry. 2016 Jun;21(6):806-12 – reference: 23880448 - J Affect Disord. 2014 Jan;152-154:122-30 – reference: 26794186 - Multivariate Behav Res. 1980 Jul 1;15(3):335-52 – reference: 26204801 - Psychol Med. 2015 Dec;45(16):3517-26 – reference: 12615092 - Child Abuse Negl. 2003 Feb;27(2):169-90 – reference: 3085570 - Annu Rev Neurosci. 1986;9:357-81 – reference: 12804127 - J Child Adolesc Psychopharmacol. 2003 Spring;13(1):65-73 – reference: 15177086 - Eur Psychiatry. 2002 Jul;17 Suppl 3:306-10 – reference: 14512209 - Biol Psychiatry. 2003 Oct 1;54(7):693-702 – reference: 15056502 - Am J Psychiatry. 2004 Apr;161(4):598-607 – reference: 18787661 - J Psychiatry Neurosci. 2008 Sep;33(5):423-30 – reference: 19125212 - J Psychiatry Neurosci. 2009 Jan;34(1):41-54 – reference: 22112927 - Biol Psychiatry. 2012 Feb 15;71(4):286-93 – reference: 12907793 - Science. 2003 Aug 8;301(5634):805-9 – reference: 25997769 - Dev Psychopathol. 2015 May;27(2):521-33 – reference: 22426398 - Neurobiol Dis. 2013 Apr;52:24-37 |
| SSID | ssj0007214 |
| Score | 2.4685867 |
| Snippet | Childhood adversity plays an important role for development of major depressive disorder (MDD). There are differences in subcortical brain structures between... Abstract Childhood adversity plays an important role for development of major depressive disorder (MDD). There are differences in subcortical brain structures... |
| SourceID | pubmedcentral proquest pubmed crossref elsevier |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 58 |
| SubjectTerms | Adult Adult Survivors of Child Adverse Events - psychology Antidepressive Agents - therapeutic use Brain - diagnostic imaging Brain - drug effects Caudate Childhood adversity Depression Depressive Disorder, Major - diagnostic imaging Depressive Disorder, Major - drug therapy ENIGMA Female Hippocampus Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Male Middle Aged MRI Organ Size Psychiatric Status Rating Scales Psychiatry Sex Characteristics Software Surveys and Questionnaires |
| Title | Childhood adversity impacts on brain subcortical structures relevant to depression |
| URI | https://www.clinicalkey.com/#!/content/1-s2.0-S0022395616306665 https://www.clinicalkey.es/playcontent/1-s2.0-S0022395616306665 https://dx.doi.org/10.1016/j.jpsychires.2016.11.010 https://www.ncbi.nlm.nih.gov/pubmed/27918926 https://www.proquest.com/docview/1846365787 https://pubmed.ncbi.nlm.nih.gov/PMC5564511 |
| Volume | 86 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Na9wwEB1CCqWX0vRz2zSo0KuTtSxLNj2F0LBtSQ6lgdyERpLphuINePfa394ZW3a6TQ4LvdoeJMaj0ZP05gngozShh71ZpPyfqSI0GXrlMqdDjBE1es9bAxeXenGlvl6X13twNtbCMK0y5f4hp_fZOj05Sd48uV0uucaXpjauy9QFg3AuNFfKcKwf_76jedAKR02K4fR1YvMMHK-bgVJMC1smeelj1vPkWtqHp6j7EPRfJuVfU9P5M3iaMKU4Hbp9AHuxfQ6PL9Kp-Qv4PukXCxcSDUMM5ZGdWLUC-ZoI0W2QVqL91rYYVGU31GPBl6oQ2l6L9UpMtNn2JVydf_5xtsjSXQqZ16VZZwqLKFES4PIo6xBUWVeI3jWsp6YQgwoRURlTFS5WPs7rxsjoqkL7UEgni1ew367a-AaEQ6-9mrtoQq5MGQjDNXnjHJYGtZfzGZjRfdYnoXG-7-KXHRllN_bO8ZYdT-sQS46fQT5Z3g5iGzvY1OMfsmMxKaU_SzPCDrbmIdvYpXHc2dx20s7tvVibwafJcitcd2z3wxhKlkYzH9G4Nq421F7FAm6cRWfwegityRPS1HlVS0293gq66QNWCt9-0y5_9orhJWsG5fnb_-r1O3giGdP0BLxD2KdIjO8Jka3xqB9yR_Do9Mu3xeUfpFA8nA |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Nb9QwEB2VIgEXxDfLp5G4pt04jp2IE6qoFuj2gFqpN8tje8VWKFspu1d-OzOJk7K0h5W4JhnFmozHz_GbNwAfpQkd7M0i5f9MFWGRoVcuczrEGFGj9_xrYH6qZ-fq20V5sQdHQy0M0ypT7u9zepet05XD5M3Dq-WSa3xpaeO6TF0wCC_vwF3FbQ4oqA9-X_M8aIujRslwejzReXqS12XPKaadLbO89AELenIx7e1r1E0M-i-V8q-16fgRPEygUnzux_0Y9mLzBO7N07H5U_gxChgLFxIPQ_T1ka1YNQK5T4RoN0hb0e7ftuhlZTc0YsFdVQhur8V6JUbebPMMzo-_nB3NstRMIfO6NOtMYRElSkJcHmUdgirrCtG7BQuqKcSgQkRUxlSFi5WP03phZHRVoX0opJPFc9hvVk18CcKh115NXTQhV6YMBOIW-cI5LA1qL6cTMIP7rE9K49zw4pcdKGWX9trxlh1PGxFLjp9APlpe9WobO9jUwxeyQzUp5T9LS8IOtuY229imidza3LbSTu2NYJvAp9FyK153fO-HIZQsTWc-o3FNXG3ofRUruHEancCLPrRGT0hT51UtNY16K-jGB1gqfPtOs_zZSYaXLBqU56_-a9Tv4f7sbH5iT76efn8NDyQDnI6N9wb2KSrjW4Jna3zXTb8_b5E-JQ |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Childhood+adversity+impacts+on+brain+subcortical+structures+relevant+to+depression&rft.jtitle=Journal+of+psychiatric+research&rft.au=Frodl%2C+Thomas&rft.au=Janowitz%2C+Deborah&rft.au=Schmaal%2C+Lianne&rft.au=Tozzi%2C+Leonardo&rft.date=2017-03-01&rft.issn=0022-3956&rft.eissn=1879-1379&rft.volume=86&rft.spage=58&rft.epage=65&rft_id=info:doi/10.1016%2Fj.jpsychires.2016.11.010&rft_id=info%3Apmid%2F27918926&rft.externalDocID=PMC5564511 |
| thumbnail_m | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F00223956%2Fcov200h.gif |